Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein

Gastroenterology

Volumn 154, Issue 1, 2018, Pages 211-223.e8

  Montpellier, Claire ^a   Wychowski, Czeslaw ^a   Sayed, Ibrahim M ^b,c   Meunier, Jean Christophe ^d   Saliou, Jean Michel ^a   Ankavay, Maliki ^a   Bull, Anne ^d   Pillez, André ^a   Abravanel, Florence ^e   Helle, François ^f   Brochot, Etienne ^f   Drobecq, Hervé ^a   Farhat, Rayan ^a   Aliouat Denis, Cécile Marie ^a   Haddad, Juliano G ^a   Izopet, Jacques ^e   Meuleman, Philip ^b   Goffard, Anne ^a   Dubuisson, Jean ^a   Cocquerel, Laurence ^a  

^a UNIV LILLE   (France)

^b GHENT UNIVERSITY   (Belgium)

^c Assiut University Faculty of Medicine   (Egypt)

^d UNIVERSITÉ DE TOURS   (France)

^e CHU PURPAN   (France)

^f UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

Author keywords

Hepatitis E; Infectious Particles; ORF2 Products; PLC PRF 5 Cells

Indexed keywords

CAPSID PROTEIN; ORF2 PROTEIN, HEPATITIS E VIRUS; VIRAL PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; HEPATITIS E; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIFE CYCLE; MOUSE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CELL CULTURE TECHNIQUE; DISEASE MODEL; HEPATITIS E VIRUS; ISOLATION AND PURIFICATION; LIVER CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CAPSID PROTEINS; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; HEPATITIS E; HEPATITIS E VIRUS; HEPATOCYTES; HUMANS; MICE; VIRAL PROTEINS;

EID: 85038260185     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2017.09.020     Document Type: Article

References (35)

1. Debing, Y., Moradpour, D., Neyts, J., et al. Update on hepatitis E virology: implications for clinical practice. J Hepatol 65 (2016), 200–212.
2. Pischke, S., Hartl, J., Pas, S.D., et al. Hepatitis E virus: infection beyond the liver?. J Hepatol 66 (2017), 1082–1095.
3. Khuroo, M.S., Khuroo, M.S., Hepatitis E: an emerging global disease—from discovery towards control and cure. J Viral Hepat 23 (2016), 68–79.
4. Feng, Z., Hensley, L., McKnight, K.L., et al. A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature 496 (2013), 367–371.
5. Okamoto, H., Culture systems for hepatitis E virus. J Gastroenterol 48 (2012), 147–158.
6. Shukla, P., Nguyen, H.T., Faulk, K., et al. Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination. J Virol 86 (2012), 5697–5707.
7. Emerson, S.U., Nguyen, H., Graff, J., et al. In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein. J Virol 78 (2004), 4838–4846.
8. Meuleman, P., Libbrecht, L., De Vos, R., et al. Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera. Hepatology 41 (2005), 847–856.
9. Sayed, I.M., Verhoye, L., Cocquerel, L., et al. Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver. Gut 66 (2017), 920–929.
10. Zafrullah, M., Ozdener, M.H., Panda, S.K., et al. The ORF3 protein of hepatitis E virus is a phosphoprotein that associates with the cytoskeleton. J Virol 71 (1997), 9045–9053.
11. Nagashima, S., Jirintai, S., Takahashi, M., et al. Hepatitis E virus egress depends on the exosomal pathway, with secretory exosomes derived from multivesicular bodies. J Gen Virol 95 (2014), 2166–2175.
12. Allweiss, L., Gass, S., Giersch, K., et al. Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation. J Hepatol 64 (2016), 1033–1040.
13. van de Garde, M.D.B., Pas, S.D., van der Net, G., et al. Hepatitis E virus (HEV) genotype 3 infection of human liver chimeric mice as a model for chronic HEV infection. J Virol 90 (2016), 4394–4401.
14. Sayed, I.M., Foquet, L., Verhoye, L., et al. Transmission of hepatitis E virus infection to human-liver chimeric FRG mice using patient plasma. Antiviral Res 141 (2017), 150–154.
15. Shukla, P., Nguyen, H.T., Torian, U., et al. Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant. Proc Natl Acad Sci U S A 108 (2011), 2438–2443.
16. Piver, E., Boyer, A., Gaillard, J., et al. Ultrastructural organisation of HCV from the bloodstream of infected patients revealed by electron microscopy after specific immunocapture. Gut 66 (2017), 1487–1495.
17. Balayan, M.S., Andjaparidze, A.G., Savinskaya, S.S., et al. Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route. Intervirology 20 (1983), 23–31.
18. Klausner, R.D., Donaldson, J.G., Lippincott-Schwartz, J., Brefeldin A: insights into the control of membrane traffic and organelle structure. J Cell Biol 116 (1992), 1071–1080.
19. Gallien, S., Perrodou, E., Carapito, C., et al. Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol. Genome Res 19 (2008), 128–135.
20. Qi, Y., Zhang, F., Zhang, L., et al. Hepatitis E virus produced from cell culture has a lipid envelope. PLoS One, 10, 2015, e0132503.
21. Shiota, T., Li, T.C., Yoshizaki, S., et al. Establishment of hepatitis E virus infection-permissive and -non-permissive human hepatoma PLC/PRF/5 subclones. Microbiol Immunol 59 (2015), 89–94.
22. Jameel, S., Zafrullah, M., Ozdener, M.H., et al. Expression in animal cells and characterization of the hepatitis E virus structural proteins. J Virol 70 (1996), 207–216.
23. Torresi, J., Meanger, J., Lambert, P., et al. High level expression of the capsid protein of hepatitis E virus in diverse eukaryotic cells using the Semliki Forest virus replicon. J Virol Methods 69 (1997), 81–91.
24. Zafrullah, M., Ozdener, M.H., Kumar, R., et al. Mutational analysis of glycosylation, membrane translocation, and cell surface expression of the hepatitis E virus ORF2 protein. J Virol 73 (1999), 4074–4082.
25. Graff, J., Zhou, Y.-H., Torian, U., et al. Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles. J Virol 82 (2008), 1185–1194.
26. Trémeaux, P., Lhomme, S., Chapuy-Regaud, S., et al. Performance of an antigen assay for diagnosing acute hepatitis E virus genotype 3 infection. J Clin Virol 79 (2016), 1–5.
27. Zhao, C., Geng, Y., Harrison, T.J., et al. Evaluation of an antigen-capture EIA for the diagnosis of hepatitis E virus infection. J Viral Hepat 22 (2015), 957–963.
28. Behrendt, P., Bremer, B., Todt, D., et al. Hepatitis E virus (HEV) ORF2 antigen levels differentiate between acute and chronic HEV Infection. J Infect Dis 214 (2016), 361–368.
29. Geng, Y., Zhao, C., Huang, W., et al. Detection and assessment of infectivity of hepatitis E virus in urine. J Hepatol 64 (2016), 37–43.
30. Graff, J., Nguyen, H., Yu, C., et al. The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques. J Virol 79 (2005), 6680–6689.
31. Rocha-Perugini, V., Montpellier, C., Delgrange, D., et al. The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS One, 3, 2008, e1866.
32. Abravanel, F., Sandres-Saune, K., Lhomme, S., et al. Genotype 3 diversity and quantification of hepatitis E virus RNA. J Clin Microbiol 50 (2012), 897–902.
33. Sayed, I.M., Verhoye, L., Cocquerel, L., et al. Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver. Gut 66 (2017), 920–929.
34. Barthe, P., Veyron-Churlet, R., de Visch, A., et al. Mycobacterium tuberculosis LppM displays an original structure and domain composition linked to a dual localization. Structure 24 (2016), 1788–1794.
35. Gallien, S., Perrodou, E., Carapito, C., et al. Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol. Genome Res 19 (2009), 128–135.