Hepatitis E: An emerging global disease - From discovery towards control and cure

Journal of Viral Hepatitis

Volumn 23, Issue 2, 2016, Pages 68-79

  Khuroo, Mehnaaz S ^a   Khuroo, Mohammad S ^b,c  

^a GOVERNMENT MEDICAL COLLEGE   (India)

^b SHER I KASHMIR INSTITUTE OF MEDICAL SCIENCES   (India)

^c Digestive Diseases Centre   (India)

Author keywords

communicable diseases; discovery; hepatitis E; hepatitis E virus; vaccine; zoonosis

Indexed keywords

HEPATITIS E 239 VACCINE; HEPATITIS E VACCINE; RIBAVIRIN; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; HEPATITIS VACCINE; VIRUS RNA;

AUTOCHTHONOUS HEPATITIS E; BLOOD DONOR; BLOOD TRANSFUSION; CHRONIC HEPATITIS; DEER; DIAGNOSTIC PROCEDURE; DISEASE COURSE; DOMESTIC ANIMAL; DRUG EFFICACY; DRUG SAFETY; END STAGE LIVER DISEASE; ENVIRONMENTAL SANITATION; ENZYME IMMUNOASSAY; FOOD INTAKE; GENETIC HETEROGENEITY; HEALTH CARE DELIVERY; HEALTH CARE SYSTEM; HEPATITIS E; HEPATITIS E VIRUS; HEPATITIS E VIRUS GENOTYPE 3; HEPATITIS E VIRUS GENOTYPE 4; HEPEVIRIDAE; HUMAN; INDUSTRIALIZATION; INFECTION CONTROL; LIVER CIRRHOSIS; MONOTHERAPY; NONHUMAN; NUCLEIC ACID TEST; ORTHOHEPEVIRUS A; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PIG; PISCIHEPEVIRUS; PRIORITY JOURNAL; PUBLIC HEALTH; RAW MEAT; REVIEW; SCREENING; VIROLOGY; VIRUS TRANSMISSION; WILD ANIMAL; ZOONOSIS; ANIMAL; CLASSIFICATION; GENETICS; IMMUNOLOGY; LIVER; PATHOLOGY; TRANSMISSION;

ANIMALS; ANTIVIRAL AGENTS; HEPATITIS E; HEPATITIS E VIRUS; HUMANS; LIVER; RIBAVIRIN; RNA, VIRAL; VIRAL HEPATITIS VACCINES; ZOONOSES;

EID: 84955706618     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12445     Document Type: Review

References (61)

1. Khuroo MS,. Discovery of hepatitis E: the epidemic non-A, non-B hepatitis 30 years down the memory lane. Virus Res 2011; 161 (1): 3-14.
2. Rein DB, Stevens GA, Theaker J, Wittenborn JS, Wiersma ST,. The global burden of hepatitis E virus genotypes 1 and 2 in 2005. Hepatology 2012; 55 (4): 988-997.
3. Khuroo MS, Khuroo MS,. Seroepidemiology of a second epidemic of hepatitis E in a population that had recorded first epidemic 30 years before and has been under surveillance since then. Hepatol Int 2010; 4 (2): 494-499. Erratum at: Hepatol Int 2010;4(2):536
4. Labrique AB, Zaman K, Hossain Z, et al,. Epidemiology and risk factors of incident hepatitis E virus infection in rural Bangladesh. Am J Epidemiol 2010; 172: 952-961.
5. Khuroo MS, Kamili S, Dar MY, Moecklii R, Jameel S,. Hepatitis E and long term antibody status. Lancet 1993; 341: 355.
6. Seriwatana J, Shrestha MP, Scott RM, et al,. Clinical and epidemiological relevance of quantitating hepatitis E virus-specific immunoglobulin M. Clin Diagn Lab Immunol 2002; 9 (5): 1072-1078.
7. Pischke S, Behrendt P, Bock CT, Jilg W, Manns MP, Wedemeyer H,. Hepatitis E in Germany-an under-reported infectious disease. Dtsch Arztebl Int 2014; 111 (35-36): 577-583.
8. Beale MA, Tettmar K, Szypulska R, Tedder RS, Ijaz S,. Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors? Vox Sang 2011; 100 (3): 340-342.
9. Khuroo MS,. Discovery of hepatitis E: the untold story. JK-Pract 2004; 11 (4): 291-294. [video at www.drkhuroo.com ]
10. Khuroo MS,. Study of an epidemic of non-A, non-B hepatitis: possibility of another human hepatitis virus distinct from post transfusion non-A, non-B type. Am J Med 1980; 68: 818-823.
11. Khuroo MS,. Hepatitis E: the enterically transmitted non-A, non-B hepatitis. Ind J Gastroenterol 1991; 10 (3): 96-100.
12. Khuroo MS, Teli MR, Skidmore S, Sofi MA, Khuroo M,. Incidence and severity of viral hepatitis in pregnancy. Am J Med 1981; 70: 252-255.
13. Khuroo MS, Saleem M, Teli MR, Sofi MA,. Failure to detect chronic liver disease after epidemic non-A, non-B hepatitis. Lancet 1980; 2 (8185): 97-98.
14. Khuroo MS, Kamili S, Jameel S,. Vertical transmission of hepatitis E virus. Lancet 1995; 345: 1025-1028.
15. Khuroo MS, Duermeyer W, Zargar SA, Ahanger MA, Shah MA,. Acute sporadic Non-A, non-B hepatitis in India. Am J Epidemiol 1983; 118: 360-364.
16. Purdy MA, Khudyakov YE,. Evolutionary history and population dynamics of hepatitis E virus. PLoS ONE 2010; 5 (12): e14376.
17. Ahmad I, Holla RP, Jameel S,. Molecular virology of hepatitis E virus. Virus Res 2011; 161: 47-58.
18. Cao D, Meng X-J,. Molecular biology and replication of hepatitis E virus. Emerg Microbes Infect 2012; 1: e17.
19. Smith DB, Simmonds P, Jameel S, et al,. Consensus proposals for classification of the family Hepeviridae. J Gen Virol 2014; 95: 2223-2232.
20. Khuroo MS, Rustgi VK, Dawson GJ, et al,. Spectrum of hepatitis E infection in India. J Med Virol 1994; 43: 281-286.
21. Khuroo MS, Kamili S,. Etiology and prognostic factors of acute liver failure in India. J Viral Hepat 2003; 10: 224-231.
22. Khuroo MS, Kamili S,. Etiology, clinical course and outcome of sporadic viral hepatitis in pregnancy. J Viral Hepat 2003; 10: 61-69.
23. Kumar A, Saraswat VA,. Hepatitis E and acute-on-chronic liver failure. J Clin Exp Hepatol 2013; 3 (3): 225-230.
24. Khuroo MS, Kamili S, Khuroo MS,. Clinical course and duration of viremia in vertically transmitted hepatitis E virus (HEV) infection in babies born to HEV-infected mothers. J Viral Hepat 2009; 16: 519-523.
25. Khuroo MS, Khuroo MS,. Sanitation and sewage disposal in India. JK-Pract 2015; 20 (1-2): 43-48.
26. Khuroo MS, Dar MY,. Hepatitis E: evidence for Person-to-Person transmission and inability of low dose immune serum globulin from an Indian source to prevent it. Ind J Gastroenterol 1992; 11 (3): 113-116.
27. Navaneethan U, Al Mohajer M, Shata MT,. Hepatitis E and pregnancy-understanding the pathogenesis. Liver Int 2008; 28 (9): 1190-1199.
28. Khuroo MS, Kamili S,. Association of severity of hepatitis E virus infection in the mother and vertically transmitted infection in the fetus. JK-Pract 2006; 13 (2): 70-74.
29. Khuroo MS, Kamili S, Yattoo GN,. Hepatitis E virus infection may be transmitted through blood transfusion in an endemic area. J Gastroenterol Hepatol 2004; 19: 778-784.
30. Matsubayashi K, Nagaoka Y, Sakata H, et al,. Transfusion-transmitted hepatitis E caused by apparently indigenous hepatitis E virus strain in Hokkaido, Japan. Transfusion 2004; 44: 934-940.
31. Boxall E, Herborn A, Kochethu G, et al,. Transfusion-transmitted hepatitis E in 'nonhyperendemic' country. Transfus Med 2006; 16: 79-83.
32. Hewitt PE, Ijaz S, Brailsford SR, et al,. Hepatitis E virus in blood components: a prevalence and transmission study in southeast England. Lancet 2014; 384 (9956): 1766-1773.
33. Bajpai M, Gupta E,. Transfusion transmitted hepatitis E: is screening warranted? Indian J Med Microbiol 2011; 29: 353-358.
34. Gallian P, Piquet Y, Assal A, et al,. Hepatitis E virus: blood transfusion implications. Transfus Clin Biol 2014; 21 (45): 173-177.
35. Vollmer T, Diekmann J, Johne R, Eberhardt M, Knabbe C, Dreiera J,. Novel approach for detection of hepatitis E virus infection in German blood donors. J Clin Microbiol 2012; 50: 2708-2713.
36. Bayliss SA, Gartner T, Nick S, et al,. Occurrence of hepatitis E virus RNA in plasma donations from Sweden, Germany and the United States. Vox Sang 2012; 103: 89-90.
37. Pawlotsky JM,. Hepatitis E screening for blood donations: an urgent need? Lancet 2014; 384 (9956): 1729-1730.
38. Kamar N, Dalton HR, Abravanel F, Izopet J,. Hepatitis E virus infection. Clin Microbiol Rev 2014; 27: 116-138.
39. Khuroo MS, Khuroo MS,. Hepatitis E virus. Curr Opin Infect Dis 2008; 21: 539-543.
40. Haagsma EB, Niesters HG, van den Berg AP, et al,. Prevalence of hepatitis E virus infection in liver transplant recipients. Liver Transpl 2009; 15 (10): 1225-1228.
41. Kamar N, Garrouste C, Haagsma EB, et al,. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants. Gastroenterology 2011; 140 (5): 1481-1489.
42. Yugo DM, Meng X-J,. Hepatitis E virus: foodborne, waterborne and zoonotic transmission. Int J Environ Res Public Health 2013; 10 (10): 4507-4533.
43. Kamar N, Izopet J, Dalton HR,. Chronic hepatitis E virus infection and treatment. J Clin Exp Hepatol 2013; 3: 134-140.
44. Khudyakov Y, Kamili S,. Serological diagnosis of hepatitis E virus infection. Virus Res 2011; 161: 84-92.
45. Mirazo S, Ramos N, Mainardi V, Gerona S, Arbiza J,. Transmission, diagnosis, and management of hepatitis E: an update. Hepat Med Evid Res 2014; 6: 45-59.
46. Kamili S,. Towards the development of a hepatitis E vaccine. Virus Res 2011; 161: 93-100.
47. Zhu FC, Zhang J, Zhang XF, et al,. Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large scale, randomized, double-blind placebo-controlled phase 3 trial. Lancet 2010; 376: 895-902.
48. Zhang J, Zhang XF, Huang SJ, et al,. Long term efficacy of a hepatitis E vaccine. N Engl J Med 2015; 372: 914-922.
49. Wu T, Zhu FC, Huang SJ, et al,. Safety of the hepatitis E vaccine for pregnant women: a preliminary analysis. Hepatology 2012; 55: 2038.
50. WHO Geneva. Weekly Epidemiological Record 1st May 2015. Hepatitis E vaccine. Geneva: WHO, 2015. position paper No. 18. 90;185-200. http://www.who.int/wer
51. Arankalle VA, Chobe LP,. Retrospective analysis of blood transfusion recipients: evidence for post-transfusion hepatitis E. Vox Sang 2000; 79 (2): 72-74.
52. Gotanda Y, Iwata A, Ohnuma H, et al,. Ongoing subclinical infection of hepatitis E virus among blood donors with an elevated alanine aminotransferase level in Japan. J Med Virol 2007; 79 (6): 734-742.
53. Juhl D, Baylis SA, Blumel J, et al,. Seroprevalence and incidence of hepatitis E virus infection in German blood donors. Transfusion 2013; doi: 10.1111/trf.12121.
54. Ren F, Zhao C, Wang L, et al,. Hepatitis E virus seroprevalence and molecular study among blood donors in China. Transfusion 2014; 54 (3 Pt 2): 910-917.
55. Hogema BM, Molier M, Slot E, Zaaijer HL,. Past and present of hepatitis E in the Netherlands. Transfusion 2014; 54 (12): 3092-3096.
56. Fischer C, Hofmann M, Danzer M, Hofer K, Kaar J, Gabriel C,. Seroprevalence and Incidence of hepatitis E in blood donors in Upper Austria. PLoS One 2015; 10 (3): e0119576.
57. International Committee on Taxonomy of Viruses; Hepatitis E virus. 1995. http://www.ictvonline.org/virusTaxInfo.asp
58. International Committee on Taxonomy of Viruses; Hepatitis E virus. 1998. http://www.ictvonline.org/virusTaxInfo.asp
59. International Committee on Taxonomy of Viruses; Hepatitis E virus. 2004. http://www.ictvonline.org/virusTaxInfo.asp
60. International Committee on Taxonomy of Viruses; Hepatitis E virus. 2009. http://www.ictvonline.org/virusTaxInfo.asp
61. International Committee on Taxonomy of Viruses; Hepatitis E virus. 2015. http://www.ictvonline.org/virusTaxInfo.asp