Outcomes of ICU patients with a discharge diagnosis of critical illness polyneuromyopathy: A propensity-matched analysis

Critical Care Medicine

Volumn 45, Issue 12, 2017, Pages 2055-2060

  Kelmenson, Daniel A ^a   Held, Natalie ^a   Allen, Richard R ^a,b   Quan, Dianna ^a   Burnham, Ellen L ^a   Clark, Brendan J ^a   Ho, P Michael ^a,c   Kiser, Tyree H ^a,c   Vandivier, R William ^a   Moss, Marc ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Peak Statistical Services   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Critical care; Critical care outcomes; Critical illness; Muscle weakness; Polyneuropathies

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTIFICIAL VENTILATION; CLINICAL TRIAL; FEMALE; HOSPITAL CHARGE; HOSPITAL DISCHARGE; HOSPITAL MORTALITY; HOSPITAL READMISSION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MALE; MIDDLE AGED; MULTICENTER STUDY; MUSCLE DISEASE; POLYNEUROPATHY; PROPENSITY SCORE; RETROSPECTIVE STUDY; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; TIME FACTOR; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HOSPITAL CHARGES; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; LOGISTIC MODELS; MALE; MIDDLE AGED; MUSCULAR DISEASES; PATIENT DISCHARGE; PATIENT READMISSION; POLYNEUROPATHIES; PROPENSITY SCORE; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; TIME FACTORS; YOUNG ADULT;

EID: 85038251462     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000002763     Document Type: Article

References (28)

1. Fan E, Cheek F, Chlan L, et al; ATS Committee on ICU-acquired Weakness in Adults; American Thoracic Society: An official American Thoracic Society Clinical Practice guideline: The diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med 2014; 190:1437-1446
2. Stevens RD, Marshall SA, Cornblath DR, et al: A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med 2009; 37:S299-S308
3. de Jonghe B, Lacherade JC, Sharshar T, et al: Intensive care unitacquired weakness: Risk factors and prevention. Crit Care Med 2009; 37:S309-S315
4. Schefold JC, Bierbrauer J, Weber-Carstens S: Intensive care unitacquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock. J Cachexia Sarcopenia Muscle 2010; 1:147-157
5. Batt J, dos Santos CC, Cameron JI, et al: Intensive care unit-acquired weakness: Clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med 2013; 187:238-246
6. De Jonghe B, Sharshar T, Lefaucheur JP, et al; Groupe de Réflexion et d'Etude des Neuromyopathies en Réanimation: Paresis acquired in the intensive care unit: A prospective multicenter study. JAMA 2002; 288:2859-2867
7. Ali NA, O'Brien JM Jr, Hoffmann SP, et al; Midwest Critical Care Consortium: Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med 2008; 178:261-268
8. Latronico N, Bolton CF: Critical illness polyneuropathy and myopathy: A major cause of muscle weakness and paralysis. Lancet Neurol 2011; 10:931-941
9. Bednarik J, Lukas Z, Vondracek P: Critical illness polyneuromyopathy: The electrophysiological components of a complex entity. Intensive Care Med 2003; 29:1505-1514
10. Khan J, Harrison TB, Rich MM, et al: Early development of critical illness myopathy and neuropathy in patients with severe sepsis. Neurology 2006; 67:1421-1425
11. Moss M, Yang M, Macht M, et al: Screening for critical illness polyneuromyopathy with single nerve conduction studies. Intensive Care Med 2014; 40:683-690
12. Latronico N, Bertolini G, Guarneri B, et al: Simplified electrophysiological evaluation of peripheral nerves in critically ill patients: The Italian multi-centre CRIMYNE study. Crit Care 2007; 11:R11
13. Latronico N, Nattino G, Guarneri B, et al; GiVITI Study Investigators: Validation of the peroneal nerve test to diagnose critical illness polyneuropathy and myopathy in the intensive care unit: The multicentre Italian CRIMYNE-2 diagnostic accuracy study. F1000Res 2014; 3:127
14. Schweickert WD, Pohlman MC, Pohlman AS, et al: Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial. Lancet 2009; 373:1874-1882
15. Puthucheary ZA, Rawal J, McPhail M, et al: Acute skeletal muscle wasting in critical illness. JAMA 2013; 310:1591-1600
16. Hermans G, Wilmer A, Meersseman W, et al: Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med 2007; 175:480-489
17. Sharshar T, Bastuji-Garin S, Stevens RD, et al; Groupe de Réflexion et d'Etude des Neuromyopathies En Réanimation: Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med 2009; 37:3047-3053
18. Rudis MI, Guslits BJ, Peterson EL, et al: Economic impact of prolonged motor weakness complicating neuromuscular blockade in the intensive care unit. Crit Care Med 1996; 24:1749-1756
19. Garnacho-Montero J, Amaya-Villar R, García-Garmendía JL, et al: Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients. Crit Care Med 2005; 33:349-354
20. Connolly BA, Jones GD, Curtis AA, et al: Clinical predictive value of manual muscle strength testing during critical illness: An observational cohort study. Crit Care 2013; 17:R229
21. Hermans G, Van Mechelen H, Clerckx B, et al: Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med 2014; 190:410-420
22. Agoritsas T, Merglen A, Shah ND, et al: Adjusted analyses in studies addressing therapy and harm: Users' guides to the medical literature. JAMA 2017; 317:748-759
23. Miller DP, Gomberg-Maitland M, Humbert M: Survivor bias and risk assessment. Eur Respir J 2012; 40:530-532
24. Grimes DA, Schulz KF: Bias and causal associations in observational research. Lancet 2002; 359:248-252
25. Field-Ridley A, Dharmar M, Steinhorn D, et al: ICU-acquired weakness is associated with differences in clinical outcomes in critically ill children. Pediatr Crit Care Med 2016; 17:53-57
26. Lone NI, Walsh TS: Impact of intensive care unit organ failures on mortality during the five years after a critical illness. Am J Respir Crit Care Med 2012; 186:640-647
27. Lone NI, Gillies MA, Haddow C, et al: Five-year mortality and hospital costs associated with surviving intensive care. Am J Respir Crit Care Med 2016; 194:198-208
28. Iwashyna TJ, Hodgson CL, Pilcher D, et al: Timing of onset and burden of persistent critical illness in Australia and New Zealand: A retrospective, population-based, observational study. Lancet Respir Med 2016; 4:566-573