Commonly Used Patient-Reported Outcomes Do Not Improve Prediction of COPD Exacerbations: A Multicenter 4½ Year Prospective Cohort Study

Chest

Volumn 152, Issue 6, 2017, Pages 1179-1187

  Strassmann, Alexandra ^a   Frei, Anja ^a   Haile, Sarah R ^a   ter Riet, Gerben ^b   Puhan, Milo A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

COPD; COPD exacerbation; index; patient reported outcome

Indexed keywords

AGED; AIRWAY OBSTRUCTION; ANXIETY; BODY MASS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CHRONIC RESPIRATORY QUESTIONNAIRE; COHORT ANALYSIS; CONFERENCE PAPER; DISEASE EXACERBATION; DYSPNEA; FATIGUE; FEMALE; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; LASA PHYSICAL ACTIVITY QUESTIONNAIRE; MAJOR CLINICAL STUDY; MALE; PATIENT-REPORTED OUTCOME; PHYSICAL ACTIVITY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; ADULT; CLINICAL TRIAL; CROSS-SECTIONAL STUDY; FOLLOW UP; MIDDLE AGED; MORBIDITY; MULTICENTER STUDY; NETHERLANDS; PROSPECTIVE STUDY; SURVIVAL RATE; SWITZERLAND; TIME FACTOR; TRENDS;

ADULT; AGED; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MORBIDITY; NETHERLANDS; PATIENT REPORTED OUTCOME MEASURES; PROGNOSIS; PROSPECTIVE STUDIES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SURVIVAL RATE; SWITZERLAND; TIME FACTORS;

EID: 85038251180     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2017.09.003     Document Type: Conference Paper

References (48)

1. World Health Organization. The Global Burden of Disease: 2004 Update. Geneva, Switzerland; 2004.
2. Guerra, B., Gaveikaite, V., Bianchi, C., Puhan, M.A., Prediction models for exacerbations in patients with COPD. Eur Respir Rev, 26(143), 2017, 160061.
3. Jones, R.C., Donaldson, G.C., Chavannes, N.H., et al. Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE index. Am J Respir Crit Care Med 180:12 (2009), 1189–1195.
4. Marin, J.M., Carrizo, S.J., Casanova, C., et al. Prediction of risk of COPD exacerbations by the BODE index. Respir Med 103:3 (2009), 373–378.
5. Ong, K., Earnest, A., Lu, S., A multidimensional grading system (BODE Index) as predictor of hospitalization for COPD. Chest 128:6 (2005), 3810–3816.
6. Chen, C.-Z., Ou, C.-Y., Yu, C.-H., Yang, S.-C., Chang, H.-Y., Hsiue, T.-R., Comparison of Global Initiative for Chronic Obstructive Pulmonary Disease 2013 classification and body mass index, airflow obstruction, dyspnea, and exacerbations index in predicting mortality and exacerbations in elderly adults with chronic obstructive pulmonary disease. J Am Geriatr Soc 63:2 (2015), 244–250.
7. Soler-Cataluña, J.J., Martínez-García, M.Á., Sánchez, L.S., Tordera, M.P., Sánchez, P.R., Severe exacerbations and BODE index: two independent risk factors for death in male patients with COPD. Respir Med 103:5 (2009), 692–699.
8. Make, B., Calverley, P., Jenkins, C., et al. A score to predict short-term risk of COPD exacerbations (SCOPEX). COPD J Chronic Obstr Pulm Dis 10 (2015), 201–209.
9. Vogelmeier, C.F., Criner, G.J., Martinez, F.J., et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Eur Respir J, 49(3), 2017, 1700214.
10. Laurin, C., Moullec, G., Bacon, S.L., Lavoie, K.L., Impact of anxiety and depression on chronic obstructive pulmonary disease exacerbation risk. Am J Respir Crit Care Med 185:9 (2012), 918–923.
11. Seidel, D., Cheung, A., Suh, E.S., Raste, Y., Atakhorrami, M., Spruit, M.A., Physical inactivity and risk of hospitalisation for chronic obstructive pulmonary disease. Int J Tuberc Lung Dis 16:8 (2012), 1015–1019.
12. Puhan, M.A., Behnke, M., Devereaux, P.J., et al. Measurement of agreement on health-related quality of life changes in response to respiratory rehabilitation by patients and physicians—a prospective study. Respir Med 98:12 (2004), 1195–1202.
13. Schünemann, H.J., Griffith, L., Jaeschke, R., Goldstein, R., Stubbing, D., Guyatt, G.H., Evaluation of the minimal important difference for the feeling thermometer and the St. George's Respiratory Questionnaire in patients with chronic airflow obstruction. J Clin Epidemiol 56:12 (2003), 1170–1176.
14. The EuroQol Group. EuroQol—a new facility for the measurement of health-related quality of life. Health Policy 16:3 (1990), 199–208.
15. Puhan, M.A., Guyatt, G.H., Montori, V.M., et al. The standard gamble demonstrated lower reliability than the feeling thermometer. J Clin Epidemiol 58:5 (2005), 458–465.
16. Solem, C.T., Sun, S.X., Sudharshan, L., Macahilig, C., Katyal, M., Gao, X., Exacerbation-related impairment of quality of life and work productivity in severe and very severe chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 8 (2013), 641–652.
17. Benzo, R.P., Chang, C.-C.H., Farrell, M.H., et al. Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease. Respiration 80:1 (2010), 10–18.
18. Garcia-Aymerich, J., Farrero, E., Félez, M.A., Izquierdo, J., Marrades, R.M., Antó J.M., Risk factors of readmission to hospital for a COPD exacerbation: a prospective study. Thorax 58:2 (2003), 100–105.
19. Hurst, J.R., Vestbo, J., Anzueto, A., et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 363:12 (2010), 1128–1138.
20. Manolio, T.A., Genomewide association studies and assessment of the risk of disease. N Engl J Med 363:2 (2010), 166–176.
21. Thomsen, M., Ingebrigtsen, T.S., Marott, J.L., Dahl, M., Lange, P., Vestbo, J., Inflammatory biomarkers and exacerbations. JAMA 309:22 (2013), 2353–2361.
22. Siebeling, L., ter Riet, G., van der Wal, W.M., et al. ICE COLD ERIC—International collaborative effort on chronic obstructive lung disease: exacerbation risk index cohorts—study protocol for an international COPD cohort study. BMC Pulm Med, 9, 2009, 15.
23. Siebeling, L., Puhan, M.A., Muggensturm, P., Zoller, M., ter Riet, G., Characteristics of Dutch and Swiss primary care patients with COPD—baseline data of the ICE COLD ERIC study. Clin Epidemiol 3:1 (2011), 273–283.
24. Puhan, M.A., Behnke, M., Laschke, M., et al. Self-administration and standardisation of the chronic respiratory questionnaire: a randomised trial in three German-speaking countries. Respir Med 98:4 (2004), 342–350.
25. Puhan, M.A., Behnke, M., Frey, M., et al. Self-administration and interviewer-administration of the German Chronic Respiratory Questionnaire: instrument development and assessment of validity and reliability in two randomised studies. Health Qual Life Outcomes, 2(1), 2004, 1.
26. Schünemann, H.J., Puhan, M., Goldstein, R., Jaeschke, R., Guyatt, G.H., Measurement properties and interpretability of the Chronic Respiratory Disease Questionnaire (CRQ). COPD 2:1 (2005), 81–89.
27. Guyatt, G.H., Feeny, D.H., Patrick, D.L., Measuring health-related quality of life. Ann Intern Med 118 (1993), 622–629.
28. Puhan, M.A., Frey, M., Büchi, S., Schünemann, H.J., The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease. Health Qual Life Outcomes, 6, 2008, 46.
29. Snaith, R.P., The Hospital Anxiety and Depression Scale. Heal Qual Life Outcomes, 1, 2003, 29.
30. Stel, V.S., Smit, J.H., Pluijm, S.M.F., Visser, M., Deeg, D.J.H., Lips, P., Comparison of the LASA Physical Activity Questionnaire with a 7-day diary and pedometer. J Clin Epidemiol 57:3 (2004), 252–258.
31. Puhan, M.A., Garcia-Aymerich, J., Frey, M., et al. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. Lancet 374:9691 (2009), 704–711.
32. Puhan, M. a., Hansel, N.N., Sobradillo, P., et al. Large-scale international validation of the ADO index in subjects with COPD: an individual subject data analysis of 10 cohorts. BMJ Open 2:6 (2012), 2012–2152.
33. Crook, S., Büsching, G., Schultz, K., et al. A multicentre validation of the 1-min sit-to-stand test in patients with COPD. Eur Respir J, 49(3), 2017, 1601871.
34. Ozalevli, S., Ozden, A., Itil, O., Akkoclu, A., Comparison of the sit-to-stand test with 6 min walk test in patients with chronic obstructive pulmonary disease. Respir Med 101:2 (2007), 286–293.
35. Frei, A., Siebeling, L., Wolters, C., et al. The inaccuracy of patient recall for COPD exacerbation rate estimation and its implications: results from central adjudication. Chest 150:4 (2016), 860–868.
36. Celli, B.R., Cote, C.G., Marin, J.M., et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 350:10 (2004), 1005–1012.
37. Sundh, J., Janson, C., Lisspers, K., Ställberg, B., Montgomery, S., The Dyspnoea, Obstruction, Smoking, Exacerbation (DOSE) index is predictive of mortality in COPD. Prim Care Respir J 21:3 (2012), 295–301.
38. Seemungal, T.A., Hurst, J.R., Wedzicha, J.A., Exacerbation rate, health status and mortality in COPD—a review of potential interventions. Int J COPD 4 (2009), 203–223.
39. Pencina, M.J., D'Agostino, R.B. Sr., D'Agostino, R.B. Jr., Vasan, R.S., Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 27:2 (2008), 157–172.
40. Kerr, K.F., Wang, Z., Janes, H., McClelland, R.L., Psaty, B.M., Pepe, M.S., Net reclassification indices for evaluating risk-prediction instruments: a critical review. Epidemiology 25:1 (2014), 114–121.
41. Hilden, J., Gerds, T.A., A note on the evaluation of novel biomarkers: do not rely on integrated discrimination improvement and net reclassification index. Stat Med 33:19 (2014), 3405–3414.
42. Pepe, M.S., Fan, J., Feng, Z., Gerds, T., Hilden, J., The Net Reclassification Index (NRI): a misleading measure of prediction improvement even with independent test data sets. Stat Biosci 7:2 (2015), 282–295.
43. Puhan, M.A., Siebeling, L., Zoller, M., Muggensturm, P., ter Riet, G., Simple functional performance tests and mortality in COPD. Eur Respir J 42:4 (2013), 956–963.
44. Moons, K.G.M., Kengne, A.P., Grobbee, D.E., et al. Risk prediction models: II. External validation, model updating, and impact assessment. Heart 98:9 (2012), 691–698.
45. Lloyd-Jones, D.M., Cardiovascular risk prediction: Basic concepts, current status, and future directions. Circulation 121:15 (2010), 1768–1777.
46. Garcia-Aymerich, J., Lange, P., Benet, M., Schnohr, P., Antó J.M., Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax 61:9 (2006), 772–778.
47. Gudmundsson, G., Gislason, T., Janson, C., et al. Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression. Eur Respir J 26:3 (2005), 414–419.
48. Tzoulaki, I., Liberopoulos, G., Ioannidis, J.P.A., Use of reclassification for assessment of improved prediction: an empirical evaluation. Int J Epidemiol 40:4 (2011), 1094–1105.