The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Rivas, Matilde De Las ^a   Lira Navarrete, Erandi ^a,b   Daniel, Earnest James Paul ^c   Companõn, Ismael ^d   Coelho, Helena ^e,f,g   Diniz, Ana ^e   Jiménez Barbero, Jesús ^f,g,h   Peregrina, Jesús M ^d   Clausen, Henrik ^b   Corzana, Francisco ^d   Marcelo, Filipa ^e   Jiménez Osés, Gonzalo ^d   Gerken, Thomas A ^c,i   Hurtado Guerrero, Ramon ^a,j  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF LA RIOJA   (Spain)

^e UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^f CIC BIOGUNE   (Spain)

^g UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^h BASQUE FOUNDATION FOR SCIENCE   (Spain)

ⁱ CASE WESTERN RESERVE UNIVERSITY   (United States)

^j FUNDACIÓN ARAID   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GLYCINE; GLYCOPEPTIDE; LECTIN; N ACETYLGALACTOSAMINE; POLYPEPTIDE; TRANSFERASE; N ACETYLGALACTOSAMINYLTRANSFERASE; PEPTIDE; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE; PROTEIN BINDING;

CATALYSIS; ENZYME; ENZYME ACTIVITY; PEPTIDE; REACTION KINETICS; SIMULATION;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHIMERA; ENZYME ACTIVE SITE; ENZYME GLYCOSYLATION; ENZYME KINETICS; EPITOPE MAPPING; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; GLYCOSYLATION; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; CHIMERA; CLONING, MOLECULAR; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; KINETICS; LECTINS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; N-ACETYLGALACTOSAMINYLTRANSFERASES; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; SUBSTRATE SPECIFICITY;

EID: 85037122538     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02006-0     Document Type: Article

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