Host DNases prevent vascular occlusion by neutrophil extracellular traps

Science

Volumn 358, Issue 6367, 2017, Pages 1202-1206

  Jiménez Alcázar, Miguel ^a   Rangaswamy, Chandini ^a   Panda, Rachita ^a   Bitterling, Josephine ^a   Simsek, Yashin J ^a   Long, Andy T ^a   Bilyy, Rostyslav ^b   Krenn, Veit ^c   Renné, Christoph ^d   Renné, Thomas ^a,e   Kluge, Stefan ^a   Panzer, Ulf ^a   Mizuta, Ryushin ^f   Mannherz, Hans Georg ^g   Kitamura, Daisuke ^f   Herrmann, Martin ^h   Napirei, Markus ^g   Fuchs, Tobias A ^a,e  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b DANYLO HALYTSKY LVIV NATIONAL MEDICAL UNIVERSITY   (Ukraine)

^c Zentrum fur Histologie Zytologie und Molekulare Diagnostik   (Germany)

^d Pathological Practice   (Germany)

^e KAROLINSKA INSTITUTE   (Sweden)

^f TOKYO UNIVERSITY OF SCIENCE   (Japan)

^g RUHR UNIVERSITY BOCHUM   (Germany)

^h UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; DEOXYRIBONUCLEASE I; DNASE 1 LIKE 3; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; DNA; DNASE1L3 PROTEIN, MOUSE; GRANULOCYTE COLONY STIMULATING FACTOR;

BACTERIAL DISEASE; BLOOD; CELLS AND CELL COMPONENTS; DNA; ENZYME; ENZYME ACTIVITY; HOMEOSTASIS; INFECTIOUS DISEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BLOOD VESSEL; BLOOD VESSEL OCCLUSION; CONTROLLED STUDY; EXTRACELLULAR TRAP; HUMAN; INFLAMMATION; MOUSE; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; SEPTICEMIA; ANIMAL; BLOOD; BLOOD CLOTTING DISORDER; ENZYMOLOGY; GENETICS; HEMOSTASIS; LIVER; LUNG; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY; SEPSIS; THROMBOSIS; VASCULARIZATION;

BACTERIA (MICROORGANISMS);

ANIMALS; DEOXYRIBONUCLEASE I; DNA; ENDODEOXYRIBONUCLEASES; EXTRACELLULAR TRAPS; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMOSTASIS; HEMOSTATIC DISORDERS; HUMANS; INFLAMMATION; LIVER; LUNG; MICE; MICE, MUTANT STRAINS; NEUTROPHILS; SEPSIS; THROMBOSIS;

EID: 85036528198     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aam8897     Document Type: Article

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