The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity

Journal of Biological Chemistry

Volumn 292, Issue 52, 2017, Pages 21517-21526

  McMichael, Temet M ^a   Zhang, Lizhi ^a   Chemudupati, Mahesh ^a   Hach, Jocelyn C ^a   Kenney, Adam D ^a   Hang, Howard C ^b   Yount, Jacob S ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELL CULTURE; ENZYME INHIBITION; GLYCOPROTEINS; MAMMALS; VIRUSES;

ANTIVIRAL ACTIVITIES; ANTIVIRAL RESPONSE; FUNCTIONAL REDUNDANCY; HUMAN CELL LINES; PALMITOYLTRANSFERASE; PERINUCLEAR LOCALIZATION; POST-TRANSLATIONAL MODIFICATIONS; TRANS-MEMBRANE PROTEINS;

ACYLATION;

CELL PROTEIN; CYSTEINE; INTERFERON INDUCED TRANSMEMBRANE PROTEIN 3; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZINC FINGER DHHC DOMAIN CONTAINING 1 PALMITOYLTRANSFERASE; ZINC FINGER DHHC DOMAIN CONTAINING 15 PALMITOYLTRANSFERASE; ZINC FINGER DHHC DOMAIN CONTAINING 20 PALMITOYLTRANSFERASE; ZINC FINGER DHHC DOMAIN CONTAINING 3 PALMITOYLTRANSFERASE; ZINC FINGER DHHC DOMAIN CONTAINING 7 PALMITOYLTRANSFERASE; ZINC FINGER NUCLEASE; ACYLTRANSFERASE; ANTIVIRUS AGENT; IFITM3 PROTEIN, HUMAN; INTERFERON; MEMBRANE PROTEIN; RNA BINDING PROTEIN; SIGNAL PEPTIDE; ZDHHC20 PROTEIN, HUMAN; ZDHHC7 PROTEIN, HUMAN;

ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; DNA SEQUENCE; GENE OVEREXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; INFLUENZA; LYSOSOME; NUCLEAR LOCALIZATION SIGNAL; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; VIRUS INHIBITION; ZDHHC GENE; A-549 CELL LINE; HEK293 CELL LINE; INNATE IMMUNITY; LIPOYLATION; METABOLISM; ORTHOMYXOVIRIDAE; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN TRANSPORT;

A549 CELLS; ACYLTRANSFERASES; ANTIVIRAL AGENTS; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOYLATION; MEMBRANE PROTEINS; ORTHOMYXOVIRIDAE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RNA-BINDING PROTEINS;

EID: 85034636383     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M117.800482     Document Type: Article

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