Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Artificial Cells, Nanomedicine and Biotechnology

Volumn 46, Issue 8, 2018, Pages 1659-1670

  Zhu, Jinyun ^a,b   Lu, Kai ^b,c   Zhang, Ning ^a,b   Zhao, Yun ^a,b   Ma, Qunchao ^a,b   Shen, Jian ^a,b   Lin, Yinuo ^a,b   Xiang, Pingping ^a,b   Tang, Yaoliang ^d   Hu, Xinyang ^a,b   Chen, Jinghai ^a,b   Zhu, Wei ^a,b   Webster, Keith A ^e   Wang, Jian’an ^a,b   Yu, Hong ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Provincial Key Laboratory of Cardiovascular Research of Zhejiang Province   (China)

^c The First People s Hospital of Huzhou   (China)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Exosomes; hypoxia; microRNA210; MSCs; myocardial infarction; nSMase2

Indexed keywords

CELL DEATH; ENDOTHELIAL CELLS; FLOWCHARTING; HEART; MAMMALS; MOLECULAR BIOLOGY; RNA; STEM CELLS;

EXOSOMES; HYPOXIA; MICRORNA210; MSCS; MYOCARDIAL INFARCTION; NSMASE2;

CELL CULTURE;

CD63 ANTIGEN; CD9 ANTIGEN; MICRORNA 210; SMALL INTERFERING RNA; SPHINGOMYELIN PHOSPHODIESTERASE; MICRORNA; MIRN210 MICRORNA, HUMAN; SMPD3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC MUSCLE; CARDIAC STEM CELL; CONTROLLED STUDY; EXOSOME; HEART INFARCTION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOFLUORESCENCE; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PHOTON CORRELATION SPECTROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ANIMAL; CARDIAC MUSCLE CELL; CELL HYPOXIA; CONDITIONED MEDIUM; METABOLISM; PATHOLOGY; PHARMACOLOGY; TRANSPLANTATION;

ANIMALS; CELL HYPOXIA; CULTURE MEDIA, CONDITIONED; EXOSOMES; MALE; MESENCHYMAL STEM CELLS; MICE; MICRORNAS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 85034211542     PISSN: 21691401     EISSN: 2169141X     Source Type: Journal    
DOI: 10.1080/21691401.2017.1388249     Document Type: Article

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