메뉴 건너뛰기




Volumn 1, Issue 6, 2017, Pages 367-379

T-cell assays confirm immunogenicity of tungsten-induced erythropoietin aggregates associated with pure red cell aplasia

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85034005405     PISSN: 24739529     EISSN: 24739537     Source Type: Journal    
DOI: 10.1182/bloodadvances.2016001842     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 84900344672 scopus 로고    scopus 로고
    • New FDA draft guidance on immunogenicity
    • Parenky A, Myler H, Amaravadi L, et al. New FDA draft guidance on immunogenicity. AAPS J. 2014;16(3):499-503.
    • (2014) AAPS J , vol.16 , Issue.3 , pp. 499-503
    • Parenky, A.1    Myler, H.2    Amaravadi, L.3
  • 2
    • 84904612447 scopus 로고    scopus 로고
    • Strategic characterization of anti-drug antibody responses for the assessment of clinical relevance and impact
    • Tatarewicz SM, Mytych DT, Manning MS, Swanson SJ, Moxness MS, Chirmule N. Strategic characterization of anti-drug antibody responses for the assessment of clinical relevance and impact. Bioanalysis. 2014;6(11):1509-1523.
    • (2014) Bioanalysis , vol.6 , Issue.11 , pp. 1509-1523
    • Tatarewicz, S.M.1    Mytych, D.T.2    Manning, M.S.3    Swanson, S.J.4    Moxness, M.S.5    Chirmule, N.6
  • 3
    • 84861337214 scopus 로고    scopus 로고
    • Immunogenicity of protein aggregates–concerns and realities
    • Wang W, Singh SK, Li N, Toler MR, King KR, Nema S. Immunogenicity of protein aggregates–concerns and realities. Int J Pharm. 2012;431(1-2):1-11.
    • (2012) Int J Pharm , vol.431 , Issue.1-2 , pp. 1-11
    • Wang, W.1    Singh, S.K.2    Li, N.3    Toler, M.R.4    King, K.R.5    Nema, S.6
  • 4
    • 84897869100 scopus 로고    scopus 로고
    • Immunogenicity of therapeutic proteins: Influence of aggregation
    • Ratanji KD, Derrick JP, Dearman RJ, Kimber I. Immunogenicity of therapeutic proteins: influence of aggregation. J Immunotoxicol. 2014;11(2):99-109.
    • (2014) J Immunotoxicol , vol.11 , Issue.2 , pp. 99-109
    • Ratanji, K.D.1    Derrick, J.P.2    Dearman, R.J.3    Kimber, I.4
  • 5
    • 84864103186 scopus 로고    scopus 로고
    • Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses
    • Joubert MK, Hokom M, Eakin C, et al. Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses. J Biol Chem. 2012;287(30):25266-25279.
    • (2012) J Biol Chem , vol.287 , Issue.30 , pp. 25266-25279
    • Joubert, M.K.1    Hokom, M.2    Eakin, C.3
  • 6
    • 84898642873 scopus 로고    scopus 로고
    • Aggregation of human recombinant monoclonal antibodies influences the capacity of dendritic cells to stimulate adaptive T-cell responses in vitro
    • published correction PLoS One. 2014;9(3):e93339
    • Rombach-Riegraf V, Karle AC, Wolf B, et al. Aggregation of human recombinant monoclonal antibodies influences the capacity of dendritic cells to stimulate adaptive T-cell responses in vitro [published correction appears in PLoS One. 2014;9(3):e93339]. PLoS One. 2014;9(1):e86322.
    • (2014) PLoS One , vol.9 , Issue.1
    • Rombach-Riegraf, V.1    Karle, A.C.2    Wolf, B.3
  • 7
    • 84888022850 scopus 로고    scopus 로고
    • T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation
    • Jawa V, Cousens LP, Awwad M, Wakshull E, Kropshofer H, De Groot AS. T-cell dependent immunogenicity of protein therapeutics: preclinical assessment and mitigation. Clin Immunol. 2013;149(3):534-555.
    • (2013) Clin Immunol , vol.149 , Issue.3 , pp. 534-555
    • Jawa, V.1    Cousens, L.P.2    Awwad, M.3    Wakshull, E.4    Kropshofer, H.5    de Groot, A.S.6
  • 8
    • 84925507517 scopus 로고    scopus 로고
    • Small amounts of sub-visible aggregates enhance the immunogenic potential of monoclonal antibody therapeutics
    • Ahmadi M, Bryson CJ, Cloake EA, et al. Small amounts of sub-visible aggregates enhance the immunogenic potential of monoclonal antibody therapeutics. Pharm Res. 2015;32(4):1383-1394.
    • (2015) Pharm Res , vol.32 , Issue.4 , pp. 1383-1394
    • Ahmadi, M.1    Bryson, C.J.2    Cloake, E.A.3
  • 9
    • 84983418557 scopus 로고    scopus 로고
    • Use of in vitro assays to assess immunogenicity risk of antibody-based biotherapeutics
    • Joubert MK, Deshpande M, Yang J, et al. Use of in vitro assays to assess immunogenicity risk of antibody-based biotherapeutics. PLoS One. 2016;11(8): e0159328.
    • (2016) PLoS One , vol.11 , Issue.8
    • Joubert, M.K.1    Deshpande, M.2    Yang, J.3
  • 10
    • 85015007861 scopus 로고    scopus 로고
    • Pure red cell aplasia
    • Means RT Jr. Pure red cell aplasia. Blood. 2016;128(21):2504-2509.
    • (2016) Blood , vol.128 , Issue.21 , pp. 2504-2509
    • Means, R.T.1
  • 11
    • 84859424243 scopus 로고    scopus 로고
    • Antibody-mediated pure red cell aplasia in chronic kidney disease patients receiving erythropoiesisstimulating agents: New insights
    • Macdougall IC, Roger SD, de Francisco A, et al. Antibody-mediated pure red cell aplasia in chronic kidney disease patients receiving erythropoiesisstimulating agents: new insights. Kidney Int. 2012;81(8):727-732.
    • (2012) Kidney Int , vol.81 , Issue.8 , pp. 727-732
    • Macdougall, I.C.1    Roger, S.D.2    de Francisco, A.3
  • 12
    • 84855436897 scopus 로고    scopus 로고
    • Safety, immunogenicity and efficacy of subcutaneous biosimilar epoetin-a (HX575) in non-dialysis patients with renal anemia: A multi-center, randomized, double-blind study
    • Haag-Weber M, Eckardt KU, Hörl WH, Roger SD, Vetter A, Roth K. Safety, immunogenicity and efficacy of subcutaneous biosimilar epoetin-a (HX575) in non-dialysis patients with renal anemia: a multi-center, randomized, double-blind study. Clin Nephrol. 2012;77(1):8-17.
    • (2012) Clin Nephrol , vol.77 , Issue.1 , pp. 8-17
    • Haag-Weber, M.1    Eckardt, K.U.2    Hörl, W.H.3    Roger, S.D.4    Vetter, A.5    Roth, K.6
  • 13
    • 84862644490 scopus 로고    scopus 로고
    • Tungsten-induced denaturation and aggregation of epoetin alfa during primary packaging as a cause of immunogenicity
    • Seidl A, Hainzl O, Richter M, et al. Tungsten-induced denaturation and aggregation of epoetin alfa during primary packaging as a cause of immunogenicity. Pharm Res. 2012;29(6):1454-1467.
    • (2012) Pharm Res , vol.29 , Issue.6 , pp. 1454-1467
    • Seidl, A.1    Hainzl, O.2    Richter, M.3
  • 14
    • 84868529788 scopus 로고    scopus 로고
    • A detailed examination of the antibody prevalence and characteristics of anti-ESA antibodies
    • Barger TE, Wrona D, Goletz TJ, Mytych DT. A detailed examination of the antibody prevalence and characteristics of anti-ESA antibodies. Nephrol Dial Transplant. 2012;27(10):3892-3899.
    • (2012) Nephrol Dial Transplant , vol.27 , Issue.10 , pp. 3892-3899
    • Barger, T.E.1    Wrona, D.2    Goletz, T.J.3    Mytych, D.T.4
  • 15
    • 84872224042 scopus 로고    scopus 로고
    • Measurement of anti-erythropoiesis-stimulating agent IgG4 antibody as an indicator of antibody-mediated pure red cell aplasia
    • Weeraratne DK, Kuck AJ, Chirmule N, Mytych DT. Measurement of anti-erythropoiesis-stimulating agent IgG4 antibody as an indicator of antibody-mediated pure red cell aplasia. Clin Vaccine Immunol. 2013;20(1):46-51.
    • (2013) Clin Vaccine Immunol , vol.20 , Issue.1 , pp. 46-51
    • Weeraratne, D.K.1    Kuck, A.J.2    Chirmule, N.3    Mytych, D.T.4
  • 16
    • 84923770324 scopus 로고    scopus 로고
    • A brief history of T cell help to B cells
    • Crotty S. A brief history of T cell help to B cells. Nat Rev Immunol. 2015;15(3):185-189.
    • (2015) Nat Rev Immunol , vol.15 , Issue.3 , pp. 185-189
    • Crotty, S.1
  • 17
    • 84871558491 scopus 로고    scopus 로고
    • Pushing the frontiers of T-cell vaccines: Accurate measurement of human T-cell responses
    • Saade F, Gorski SA, Petrovsky N. Pushing the frontiers of T-cell vaccines: accurate measurement of human T-cell responses. Expert Rev Vaccines. 2012; 11(12):1459-1470.
    • (2012) Expert Rev Vaccines , vol.11 , Issue.12 , pp. 1459-1470
    • Saade, F.1    Gorski, S.A.2    Petrovsky, N.3
  • 18
    • 84864325057 scopus 로고    scopus 로고
    • T cell assays and MIATA: The essential minimum for maximum impact
    • Britten CM, Janetzki S, Butterfield LH, et al. T cell assays and MIATA: the essential minimum for maximum impact. Immunity. 2012;37(1):1-2.
    • (2012) Immunity , vol.37 , Issue.1 , pp. 1-2
    • Britten, C.M.1    Janetzki, S.2    Butterfield, L.H.3
  • 19
    • 20144384746 scopus 로고    scopus 로고
    • Rationally engineered therapeutic proteins with reduced immunogenicity
    • Tangri S, Mothé BR, Eisenbraun J, et al. Rationally engineered therapeutic proteins with reduced immunogenicity. J Immunol. 2005;174(6):3187-3196.
    • (2005) J Immunol , vol.174 , Issue.6 , pp. 3187-3196
    • Tangri, S.1    Mothé, B.R.2    Eisenbraun, J.3
  • 20
    • 0029161588 scopus 로고
    • T cell proliferative response induced by DNA topoisomerase I in patients with systemic sclerosis and healthy donors
    • Kuwana M, Medsger TA Jr, Wright TM. T cell proliferative response induced by DNA topoisomerase I in patients with systemic sclerosis and healthy donors. J Clin Invest. 1995;96(1):586-596.
    • (1995) J Clin Invest , vol.96 , Issue.1 , pp. 586-596
    • Kuwana, M.1    Medsger, T.A.2    Wright, T.M.3
  • 21
    • 1842611598 scopus 로고    scopus 로고
    • Evaluation of methods to detect and characterize antibodies against recombinant human erythropoietin
    • Swanson SJ, Ferbas J, Mayeux P, Casadevall N. Evaluation of methods to detect and characterize antibodies against recombinant human erythropoietin. Nephron Clin Pract. 2004;96(3):c88-c95.
    • (2004) Nephron Clin Pract , vol.96 , Issue.3 , pp. c88-c95
    • Swanson, S.J.1    Ferbas, J.2    Mayeux, P.3    Casadevall, N.4
  • 22
    • 80052145682 scopus 로고    scopus 로고
    • AcDCs enhance human antigen-specific T-cell responses
    • Martinuzzi E, Afonso G, Gagnerault MC, et al. acDCs enhance human antigen-specific T-cell responses. Blood. 2011;118(8):2128-2137.
    • (2011) Blood , vol.118 , Issue.8 , pp. 2128-2137
    • Martinuzzi, E.1    Afonso, G.2    Gagnerault, M.C.3
  • 23
    • 84921646238 scopus 로고    scopus 로고
    • Immunosuppressive effects of erythropoietin on human alloreactive T cells
    • Cravedi P, Manrique J, Hanlon KE, et al. Immunosuppressive effects of erythropoietin on human alloreactive T cells. J Am Soc Nephrol. 2014;25(9): 2003-2015.
    • (2014) J Am Soc Nephrol , vol.25 , Issue.9 , pp. 2003-2015
    • Cravedi, P.1    Manrique, J.2    Hanlon, K.E.3
  • 24
    • 0033106415 scopus 로고    scopus 로고
    • T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides
    • Abulafia-Lapid R, Elias D, Raz I, Keren-Zur Y, Atlan H, Cohen IR. T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides. J Autoimmun. 1999;12(2):121-129.
    • (1999) J Autoimmun , vol.12 , Issue.2 , pp. 121-129
    • Abulafia-Lapid, R.1    Elias, D.2    Raz, I.3    Keren-Zur, Y.4    Atlan, H.5    Cohen, I.R.6
  • 25
    • 0032880017 scopus 로고    scopus 로고
    • Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays
    • Roep BO, Atkinson MA, van Endert PM, Gottlieb PA, Wilson SB, Sachs JA. Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays. J Autoimmun. 1999;13(2):267-282.
    • (1999) J Autoimmun , vol.13 , Issue.2 , pp. 267-282
    • Roep, B.O.1    Atkinson, M.A.2    van Endert, P.M.3    Gottlieb, P.A.4    Wilson, S.B.5    Sachs, J.A.6
  • 26
    • 85006817802 scopus 로고    scopus 로고
    • No evidence for drug-specific activation of circulating T cells from patients with HLA-DRB1*07: 01-restricted lapatinib-induced liver injury
    • Faulkner L, Meng X, Naisbitt DJ, Spraggs CF, Park BK. No evidence for drug-specific activation of circulating T cells from patients with HLA-DRB1*07: 01-restricted lapatinib-induced liver injury. Chem Res Toxicol. 2016;29(12):2111-2113.
    • (2016) Chem Res Toxicol , vol.29 , Issue.12 , pp. 2111-2113
    • Faulkner, L.1    Meng, X.2    Naisbitt, D.J.3    Spraggs, C.F.4    Park, B.K.5
  • 27
    • 78649740257 scopus 로고    scopus 로고
    • Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: Position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society
    • Immunology of Diabetes Society
    • Mallone R, Mannering SI, Brooks-Worrell BM, et al; T-Cell Workshop Committee, Immunology of Diabetes Society. Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society. Clin Exp Immunol. 2011;163(1):33-49.
    • (2011) Clin Exp Immunol , vol.163 , Issue.1 , pp. 33-49
    • Mallone, R.1    Mannering, S.I.2    Brooks-Worrell, B.M.3
  • 28
    • 84936066884 scopus 로고    scopus 로고
    • Ab T cell receptors as predictors of health and disease
    • Attaf M, Huseby E, Sewell AK. ab T cell receptors as predictors of health and disease. Cell Mol Immunol. 2015;12(4):391-399.
    • (2015) Cell Mol Immunol , vol.12 , Issue.4 , pp. 391-399
    • Attaf, M.1    Huseby, E.2    Sewell, A.K.3
  • 29
    • 65249086211 scopus 로고    scopus 로고
    • The association of anti-r-HuEpo-associated pure red cell aplasia with HLA-DRB1*09-DQB1*0309
    • Praditpornsilpa K, Kupatawintu P, Mongkonsritagoon W, et al. The association of anti-r-HuEpo-associated pure red cell aplasia with HLA-DRB1*09-DQB1*0309. Nephrol Dial Transplant. 2009;24(5):1545-1549.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.5 , pp. 1545-1549
    • Praditpornsilpa, K.1    Kupatawintu, P.2    Mongkonsritagoon, W.3
  • 30
    • 42449091557 scopus 로고    scopus 로고
    • Case-control study of the association between select HLA genes and anti-erythropoietin antibody-positive pure red-cell aplasia
    • Fijal B, Ricci D, Vercammen E, et al. Case-control study of the association between select HLA genes and anti-erythropoietin antibody-positive pure red-cell aplasia. Pharmacogenomics. 2008;9(2):157-167.
    • (2008) Pharmacogenomics , vol.9 , Issue.2 , pp. 157-167
    • Fijal, B.1    Ricci, D.2    Vercammen, E.3
  • 32
    • 71649099956 scopus 로고    scopus 로고
    • Tungsten-induced protein aggregation: Solution behavior
    • Jiang Y, Nashed-Samuel Y, Li C, et al. Tungsten-induced protein aggregation: solution behavior. J Pharm Sci. 2009;98(12):4695-4710.
    • (2009) J Pharm Sci , vol.98 , Issue.12 , pp. 4695-4710
    • Jiang, Y.1    Nashed-Samuel, Y.2    Li, C.3
  • 33
    • 78649486646 scopus 로고    scopus 로고
    • Quantification of the preexisting CD4 T-cell repertoire specific for human erythropoietin reveals its immunogenicity potential
    • Delluc S, Ravot G, Maillere B. Quantification of the preexisting CD4 T-cell repertoire specific for human erythropoietin reveals its immunogenicity potential. Blood. 2010;116(22):4542-4545.
    • (2010) Blood , vol.116 , Issue.22 , pp. 4542-4545
    • Delluc, S.1    Ravot, G.2    Maillere, B.3
  • 34
    • 84874557004 scopus 로고    scopus 로고
    • Erythropoietin: Multiple targets, actions, and modifying influences for biological and clinical consideration
    • Broxmeyer HE. Erythropoietin: multiple targets, actions, and modifying influences for biological and clinical consideration. J Exp Med. 2013;210(2): 205-208.
    • (2013) J Exp Med , vol.210 , Issue.2 , pp. 205-208
    • Broxmeyer, H.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.