acDCs enhance human antigen-specific T-cell responses

Blood

Volumn 118, Issue 8, 2011, Pages 2128-2137

  Martinuzzi, Emanuela ^a,b   Afonso, Georgia ^a,b   Gagnerault, Marie Claude ^a,b   Naselli, Gaetano ^a,b   Mittag, Diana ^c   Combadière, Béhazine ^a,d   Boitard, Christian ^a,b   Chaput, Nathalie ^e,f   Zitvogel, Laurence ^e,f,g   Harrison, Leonard C ^c   Mallone, Roberto ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d SORBONNE UNIVERSITÉ   (France)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f Centre d'Investigation Clinique Biothé Rapie 507   (France)

^g Division of Pediatric Surgery   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD137 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; INFLUENZA VACCINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MELANOMA VACCINE; SMALLPOX VACCINE;

ANIMAL EXPERIMENT; ANTIGEN BINDING; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSPOT ASSAY; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOGENICITY; IMMUNOTHERAPY; INCUBATION TIME; MELANOMA; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SMALLPOX; T LYMPHOCYTE ACTIVATION; UPREGULATION; VACCINATION;

EID: 80052145682     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-12-326231     Document Type: Article

References (37)

1. Lalvani A, Pathan AA, Durkan H, et al. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet. 2001;357(9273):2017-2021.
2. Kern F, Lipira G, Gratama JW, Manca F, Roederer M. Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer. Trends Immunol. 2005; 26(9):477-484.
3. Culina S, Boitard C, Mallone R. Antigen-based immune therapeutics for type 1 diabetes: magic bullets or ordinary blanks? Clin Dev Immunol. 2011;2011:286248.
4. Brezar V, Carel JC, Boitard C, Mallone R. Beyond the hormone: insulin as an autoimmune target in type 1 diabetes [published online ahead of print June 23, 2011]. Endocr Rev. doi: 10.1210/er.2011-0010.
5. Ashton-Chess J, Giral M, Soulillou JP, Brouard S. Can immune monitoring help to minimize immunosuppression in kidney transplantation? Transpl Int. 2009;22(1):110-119.
6. Keilholz U, Martus P, Scheibenbogen C. Immune monitoring of T-cell responses in cancer vaccine development. Clin Cancer Res. 2006;12(7 pt 2):2346s-2352s.
7. Dasgupta S, Bayry J, Andre S, Dimitrov JD, Kaveri SV, Lacroix-Desmazes S. Auditing protein therapeutics management by professional APCs: toward prevention of immune responses against therapeutic proteins. J Immunol. 2008;181(3):1609-1615.
8. Mallone R, Nepom GT. MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete. Clin Immunol. 2004;110(3):232-242.
9. Geiger R, Duhen T, Lanzavecchia A, Sallusto F. Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells. J Exp Med. 2009;206(7):1525-1534.
10. Melief CJ, van der Burg SH. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat Rev Cancer. 2008;8(5):351-360.
11. Shortman K, Liu YJ. Mouse and human dendritic cell subtypes. Nat Rev Immunol. 2002;2(3):151-161.
12. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med. 1994;179(4):1109-1118.
13. Luft T, Luetjens P, Hochrein H, et al. IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells. Int Immunol. 2002;14(4):367-380.
14. Dauer M, Obermaier B, Herten J, et al. Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors. J Immunol. 2003;170(8):4069-4076.
15. Martinuzzi E, Novelli G, Scotto M, et al. The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment. Diabetes. 2008;57(5):1312-1320.
16. Mallone R, Mannering SI, Brooks-Worrell BM, et al. Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society. Clin Exp Immunol. 2011;163(1):33-49.
17. Martinuzzi E, Scotto M, Enee E, et al. Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection. J Immunol Methods. 2008;333(1-2):61-70.
18. Mannering SI, Dromey JA, Morris JS, Thearle DJ, Jensen KP, Harrison LC. An efficient method for cloning human autoantigen-specific T cells. J Immunol Methods. 2005;298(1-2):83-92.
19. Chattopadhyay PK, Yu J, Roederer M. A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles. Nat Med. 2005;11(10):1113-1117.
20. Wolfl M, Kuball J, Ho WY, et al. Activationinduced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities. Blood. 2007;110(1):201-210.
21. Mallone R, Kochik SA, Reijonen H, et al. Functional avidity directs T-cell fate in autoreactive CD4+ T cells. Blood. 2005;106(8):2798-2805.
22. Afonso G, Scotto M, Renand A, et al. Critical parameters in blood processing for T-cell assays: validation on ELISpot and tetramer platforms. J Immunol Methods. 2010;359(1-2):28-36.
23. Puissant-Lubrano B, Bossi P, Gay F, et al. Control of vaccinia virus skin lesions by long-termmaintained IFN-gamma+TNF-alpha+ effector/memory CD4+ lymphocytes in humans. J Clin Invest. 2010;120(5):1636-1644.
24. Escudier B, Dorval T, Chaput N, et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial. J Transl Med. 2005;3(1):10.
25. Wehler TC, Karg M, Distler E, et al. Rapid identification and sorting of viable virus-reactive CD4(+) and CD8(+) T cells based on antigen-triggered CD137 expression. J Immunol Methods. 2008;339(1):23-37.
26. Vogt A, Mahe B, Costagliola D, et al. Transcutaneous anti-influenza vaccination promotes both CD4 and CD8 T cell immune responses in humans. J Immunol. 2008;180(3):1482-1489.
27. Combadière B, Vogt A, Mahe B, et al. Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial. PLoS ONE. 2010;5(5):e10818.
28. Dhodapkar MV, Steinman RM, Sapp M, et al. Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells. J Clin Invest. 1999;104(2):173-180.
29. Hackstein H, Morelli AE, Thomson AW. Designer dendritic cells for tolerance induction: guided not misguided missiles. Trends Immunol. 2001;22(8):437-442.
30. Kaliński P, Schuitemaker JH, Hilkens CM, Kapsenberg ML. Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J Immunol. 1998;161(6):2804-2809.
31. Mori T, Sakatani M, Yamagishi F, et al. Specific detection of tuberculosis infection: an interferongamma-based assay using new antigens. Am J Respir Crit Care Med. 2004;170(1):59-64.
32. Schulz O, Edwards AD, Schito M, et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity. 2000;13(4):453-462.
33. Poulin LF, Salio M, Griessinger E, et al. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med. 2010;207(6):1261-1271.
34. Fourlanos S, Perry C, Gellert SA, et al. Evidence that nasal insulin induces immune tolerance to insulin in adults with autoimmune diabetes. Diabetes. 2011;60(4):1237-1245.
35. Mittag D, Proietto AI, Loudovaris T, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol. 2011;186(11):6207-6217.
36. Ho CS, Munster D, Pyke CM, Hart DN, Lopez JA. Spontaneous generation and survival of blood dendritic cells in mononuclear cell culture without exogenous cytokines. Blood. 2002;99(8):2897-2904.
37. Liu K, Victora GD, Schwickert TA, et al. In vivo analysis of dendritic cell development and homeostasis. Science. 2009;324(5925):392-397.