A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): A randomized, controlled non-inferiority trial

PLoS Medicine

Volumn 14, Issue 10, 2017, Pages

  Keitel, Kristina ^a,b,c,d   Kagoro, Frank ^e   Samaka, Josephine ^e,f   Masimba, John ^e   Said, Zamzam ^e   Temba, Hosiana ^e   Mlaganile, Tarsis ^e   Sangu, Willy ^g   Rambaud Althaus, Clotilde ^h   Gervaix, Alain ⁱ   Genton, Blaise ^a,b,d   D’Acremont, Valérie ^a,b,d  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e IFAKARA HEALTH INSTITUTE   (Tanzania)

^f Amana District Hospital   (Tanzania)

^g Ilala Municipal Council   (Tanzania)

^h MÉDECINS SANS FRONTIÈRES   (Switzerland)

ⁱ GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; PROCALCITONIN; ANTIINFECTIVE AGENT;

ALGORITHM; ANTIBIOTIC THERAPY; ARTICLE; CHILD; CLINICAL OUTCOME; CONTROLLED STUDY; FEMALE; FEVER; FOLLOW UP; HOSPITALIZATION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MORTALITY; OPEN STUDY; PNEUMONIA; POINT OF CARE TESTING; PRESCHOOL CHILD; PRESCRIPTION; RANDOMIZED CONTROLLED TRIAL; TANZANIAN; TREATMENT FAILURE; VALIDATION PROCESS; BLOOD; BREATHING; CLINICAL DECISION MAKING; CLINICAL TRIAL; COMMUNICABLE DISEASES; COMPUTER ASSISTED DIAGNOSIS; DECISION SUPPORT SYSTEM; DEVICES; DIFFERENTIAL DIAGNOSIS; HEART RATE; HOSPITAL READMISSION; MOBILE APPLICATION; MULTICENTER STUDY; NUTRITIONAL STATUS; ONSET AGE; PATHOPHYSIOLOGY; PATIENT SELECTION; POINT OF CARE SYSTEM; PREDICTIVE VALUE; REPRODUCIBILITY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SMARTPHONE; TANZANIA;

AGE OF ONSET; ALGORITHMS; ANTI-BACTERIAL AGENTS; BIOMARKERS; CHILD, PRESCHOOL; CLINICAL DECISION-MAKING; COMMUNICABLE DISEASES; DECISION SUPPORT TECHNIQUES; DIAGNOSIS, COMPUTER-ASSISTED; DIAGNOSIS, DIFFERENTIAL; FEMALE; FEVER; HEART RATE; HUMANS; INFANT; MALE; MOBILE APPLICATIONS; NUTRITIONAL STATUS; PATIENT READMISSION; PATIENT SELECTION; POINT-OF-CARE SYSTEMS; POINT-OF-CARE TESTING; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RESPIRATION; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SMARTPHONE; TANZANIA;

EID: 85032449873     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1002411     Document Type: Article

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