Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection

European Respiratory Journal

Volumn 36, Issue 3, 2010, Pages 601-607

  Burkhardt, O ^a   Ewig, S ^b   Haagen, U ^c   Giersdorf, S ^c   Hartmann, O ^c   Wegscheider, K ^d   Hummers Pradier, E ^a   Welte, T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Thoraxzentrum Ruhrgebiet ^*  (Germany)

^c BRAHMS   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Antibiotic policy; Respiratory tract infections; Therapy

Indexed keywords

AMINOPENICILLIN; ANTIBIOTIC AGENT; DOXYCYCLINE; MACROLIDE; PROCALCITONIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DRUG SAFETY; DRUG USE; FEMALE; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; OUTCOMES RESEARCH; PRESCRIPTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; RISK REDUCTION; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; CALCITONIN; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; PRIMARY HEALTH CARE; PROTEIN PRECURSORS; PULMONARY MEDICINE; RESPIRATORY TRACT INFECTIONS; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME;

EID: 77956563149     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00163309     Document Type: Article

References (16)

1. Boucher HW, Talbot GH, Bradley JS, et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009; 48: 1-12.
2. National Institute for Public Health and the Environment. The European Antimicrobial Resistance Surveillance System. www.rivm.nl/earss/ Date last updated: May 2010. Date last accessed: June 2010.
3. van de Sande-Bruinsma N, Grundmann H, Verloo D, et al. Antimicrobial drug use and resistance in Europe. Emerg Infect Dis 2008; 14: 1722-1730.
4. Goossens H, Ferech M, Vander Stichele R, et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579-578.
5. Gonzales R, Malone DC, Maselli JH, et al. Excessive antibiotic use for acute respiratory infections in the United States. Clin Infect Dis 2001; 33: 757-762. (Pubitemid 32831830)
6. Smucny J, Fahey T, Becker L, et al. Antibiotics for acute bronchitis. Cochrane Database Syst Rev 2004; Issue, 4: CD000245.
7. Christ-Crain M, Jaccard-Stolz D, Bingisser R, et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004; 363: 600-607. (Pubitemid 38264177)
8. Stolz D, Christ-Crain M, Bingisser R, et al. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 2007; 131: 9-19. (Pubitemid 46122969)
9. Christ-Crain M, Stolz D, Bingisser R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 2006; 174: 84-93. (Pubitemid 43955248)
10. Nobre V, Harbarth S, Graf JD, et al. Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial. Am J Respir Crit Care Med 2008; 177: 498-505. (Pubitemid 351442188)
11. Briel M, Schuetz P, Mueller B, et al. Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care. Arch Intern Med 2008; 168: 2000-2007.
12. Anon, ICH Harmonised Tripartite Guideline. Statistical principles for clinical trials. International Conference on Harmonisation E9 Expert Working Group. Stat Med 1999; 18: 1905-1942.
13. Macfarlane JT, Holmes WF, Macfarlane RM. Reducing reconsultations for acute lower respiratory tract illness with an information leaflet: a randomized controlled study of patients in primary care. Br J Gen Pract 1997; 47: 719-722.
14. Dowell J, Pitkethly M, Bain J, et al. A randomised controlled trial of delayed antibiotic prescribing as a strategy for managing uncomplicated respiratory tract infection in primary care. Br J Gen Pract 2001; 51: 200-205. (Pubitemid 32197362)
15. Macfarlane J, Holmes W, Gard P, et al. Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. BMJ 2002; 324: 91-94.
16. Little P, Rumsby K, Kelly J, et al. Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial. JAMA 2005; 293: 3029-3035. (Pubitemid 40965073)