메뉴 건너뛰기




Volumn 49, Issue 3, 2017, Pages

Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CATHELICIDIN; INTERLEUKIN 6; INTERLEUKIN 8; POLYPEPTIDE ANTIBIOTIC AGENT; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR; VITAMIN D; CATHELICIDIN ANTIMICROBIAL PEPTIDE; CYTOKINE;

EID: 85032380190     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.01328-2016     Document Type: Article
Times cited : (56)

References (37)
  • 1
    • 34548660457 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Rabe KF, Hurd S, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176: 532–555.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 532-555
    • Rabe, K.F.1    Hurd, S.2    Anzueto, A.3
  • 2
    • 84927138885 scopus 로고    scopus 로고
    • Hospitalized exacerbations of COPD: Risk factors and outcomes in the ECLIPSE cohort
    • Mullerova H, Maselli DJ, Locantore N, et al. Hospitalized exacerbations of COPD: risk factors and outcomes in the ECLIPSE cohort. Chest 2015; 147: 999–1007.
    • (2015) Chest , vol.147 , pp. 999-1007
    • Mullerova, H.1    Maselli, D.J.2    Locantore, N.3
  • 3
    • 66149093072 scopus 로고    scopus 로고
    • The pathology of chronic obstructive pulmonary disease
    • Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009; 4: 435–459.
    • (2009) Annu Rev Pathol , vol.4 , pp. 435-459
    • Hogg, J.C.1    Timens, W.2
  • 4
    • 80052706801 scopus 로고    scopus 로고
    • New insights into the immunology of chronic obstructive pulmonary disease
    • Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011; 378: 1015–1026.
    • (2011) Lancet , vol.378 , pp. 1015-1026
    • Brusselle, G.G.1    Joos, G.F.2    Bracke, K.R.3
  • 5
    • 84958078358 scopus 로고    scopus 로고
    • Antimicrobial peptides and innate lung defenses: Role in infectious and noninfectious lung diseases and therapeutic applications
    • Hiemstra PS, Amatngalim GD, van der Does AM, et al. Antimicrobial peptides and innate lung defenses: role in infectious and noninfectious lung diseases and therapeutic applications. Chest 2016; 149: 545–551.
    • (2016) Chest , vol.149 , pp. 545-551
    • Hiemstra, P.S.1    Amatngalim, G.D.2    Van Der Does, A.M.3
  • 6
    • 4344665018 scopus 로고    scopus 로고
    • Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression
    • Wang TT, Nestel FP, Bourdeau V, et al. Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 2004; 173: 2909–2912.
    • (2004) J Immunol , vol.173 , pp. 2909-2912
    • Wang, T.T.1    Nestel, F.P.2    Bourdeau, V.3
  • 7
    • 58149189055 scopus 로고    scopus 로고
    • Respiratory epithelial cells convert inactive vitamin D to its active form: Potential effects on host defense
    • Hansdottir S, Monick MM, Hinde SL, et al. Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 2008; 181: 7090–7099.
    • (2008) J Immunol , vol.181 , pp. 7090-7099
    • Hansdottir, S.1    Monick, M.M.2    Hinde, S.L.3
  • 8
    • 77953251177 scopus 로고    scopus 로고
    • Secretory leukocyte protease inhibitor and elafin/trappin-2: Versatile mucosal antimicrobials and regulators of immunity
    • Sallenave JM. Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity. Am J Respir Cell Mol Biol 2010; 42: 635–643.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 635-643
    • Sallenave, J.M.1
  • 9
    • 84896352857 scopus 로고    scopus 로고
    • Regulation and function of antimicrobial peptides in immunity and diseases of the lung
    • Seiler F, Lepper PM, Bals R, et al. Regulation and function of antimicrobial peptides in immunity and diseases of the lung. Protein Pept Lett 2014; 21: 341–351.
    • (2014) Protein Pept Lett , vol.21 , pp. 341-351
    • Seiler, F.1    Lepper, P.M.2    Bals, R.3
  • 10
    • 34147139491 scopus 로고    scopus 로고
    • Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum
    • Bucki R, Byfield FJ, Janmey PA. Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum. Eur Respir J 2007; 29: 624–632.
    • (2007) Eur Respir J , vol.29 , pp. 624-632
    • Bucki, R.1    Byfield, F.J.2    Janmey, P.A.3
  • 11
    • 84856645410 scopus 로고    scopus 로고
    • Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities
    • Kilsgard O, Andersson P, Malmsten M, et al. Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities. Am J Respir Cell Mol Biol 2012; 46: 240–248.
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 240-248
    • Kilsgard, O.1    Andersson, P.2    Malmsten, M.3
  • 12
    • 33750944535 scopus 로고    scopus 로고
    • The antimicrobial peptide cathelicidin interacts with airway mucus
    • Felgentreff K, Beisswenger C, Griese M, et al. The antimicrobial peptide cathelicidin interacts with airway mucus. Peptides 2006; 27: 3100–3106.
    • (2006) Peptides , vol.27 , pp. 3100-3106
    • Felgentreff, K.1    Beisswenger, C.2    Griese, M.3
  • 13
    • 0035823570 scopus 로고    scopus 로고
    • Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor
    • Taggart CC, Lowe GJ, Greene CM, et al. Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor. J Biol Chem 2001; 276: 33345–33352.
    • (2001) J Biol Chem , vol.276 , pp. 33345-33352
    • Taggart, C.C.1    Lowe, G.J.2    Greene, C.M.3
  • 14
    • 76249114693 scopus 로고    scopus 로고
    • Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation
    • Weldon S, McNally P, McElvaney NG, et al. Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation. J Immunol 2009; 183: 8148–8156.
    • (2009) J Immunol , vol.183 , pp. 8148-8156
    • Weldon, S.1    McNally, P.2    McElvaney, N.G.3
  • 15
    • 75149186564 scopus 로고    scopus 로고
    • Cathelicidin LL-37, granzymes, TGF-beta1 and cytokines levels in induced sputum from farmers with and without COPD
    • Golec M, Reichel C, Mackiewicz B, et al. Cathelicidin LL-37, granzymes, TGF-beta1 and cytokines levels in induced sputum from farmers with and without COPD. Ann Agric Environ Med 2009; 16: 289–297.
    • (2009) Ann Agric Environ Med , vol.16 , pp. 289-297
    • Golec, M.1    Reichel, C.2    Mackiewicz, B.3
  • 16
    • 84867748126 scopus 로고    scopus 로고
    • The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease
    • Jiang YY, Xiao W, Zhu MX, et al. The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease. Respir Med 2012; 106: 1680–1689.
    • (2012) Respir Med , vol.106 , pp. 1680-1689
    • Jiang, Y.Y.1    Xiao, W.2    Zhu, M.X.3
  • 17
    • 27144462218 scopus 로고    scopus 로고
    • Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation
    • Xiao W, Hsu YP, Ishizaka A, et al. Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation. Chest 2005; 128: 2316–2326.
    • (2005) Chest , vol.128 , pp. 2316-2326
    • Xiao, W.1    Hsu, Y.P.2    Ishizaka, A.3
  • 18
    • 77955002672 scopus 로고    scopus 로고
    • Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
    • Tsoumakidou M, Bouloukaki I, Thimaki K, et al. Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Exp Lung Res 2010; 36: 373–380.
    • (2010) Exp Lung Res , vol.36 , pp. 373-380
    • Tsoumakidou, M.1    Bouloukaki, I.2    Thimaki, K.3
  • 19
    • 71049141360 scopus 로고    scopus 로고
    • Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease
    • Parameswaran GI, Wrona CT, Murphy TF, et al. Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease. BMC Infect Dis 2009; 9: 178.
    • (2009) BMC Infect Dis , vol.9 , pp. 178
    • Parameswaran, G.I.1    Wrona, C.T.2    Murphy, T.F.3
  • 20
    • 80052652326 scopus 로고    scopus 로고
    • Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD
    • Parameswaran GI, Sethi S, Murphy TF. Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD. Chest 2011; 140: 611–617.
    • (2011) Chest , vol.140 , pp. 611-617
    • Parameswaran, G.I.1    Sethi, S.2    Murphy, T.F.3
  • 21
    • 84870407475 scopus 로고    scopus 로고
    • Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease
    • Mallia P, Footitt J, Sotero R, et al. Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012; 186: 1117–1124.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 1117-1124
    • Mallia, P.1    Footitt, J.2    Sotero, R.3
  • 22
    • 77951159657 scopus 로고    scopus 로고
    • Systemic inflammatory markers in COPD: Results from the Bergen COPD Cohort Study
    • Eagan TM, Ueland T, Wagner PD, et al. Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study. Eur Respir J 2010; 35: 540–548.
    • (2010) Eur Respir J , vol.35 , pp. 540-548
    • Eagan, T.M.1    Ueland, T.2    Wagner, P.D.3
  • 23
    • 84920847598 scopus 로고    scopus 로고
    • Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients
    • Tangedal S, Aanerud M, Persson LJ, et al. Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients. Respir Res 2014; 15: 138.
    • (2014) Respir Res , vol.15 , pp. 138
    • Tangedal, S.1    Aanerud, M.2    Persson, L.J.3
  • 25
    • 77956401052 scopus 로고    scopus 로고
    • LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature
    • van der Does AM, Beekhuizen H, Ravensbergen B, et al. LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature. J Immunol 2010; 185: 1442–1449.
    • (2010) J Immunol , vol.185 , pp. 1442-1449
    • Van Der Does, A.M.1    Beekhuizen, H.2    Ravensbergen, B.3
  • 26
    • 0033850269 scopus 로고    scopus 로고
    • Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: Increase of cell-associated SLPI by neutrophil elastase
    • van Wetering S, van der Linden AC, van Sterkenburg MA, et al. Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase. J Investig Med 2000; 48: 359–366.
    • (2000) J Investig Med , vol.48 , pp. 359-366
    • Van Wetering, S.1    Van Der Linden, A.C.2    Van Sterkenburg, M.A.3
  • 27
    • 0027453376 scopus 로고
    • Neutrophil elastase increases secretory leukocyte protease inhibitor transcript levels in airway epithelial cells
    • Abbinante-Nissen JM, Simpson LG, Leikauf GD. Neutrophil elastase increases secretory leukocyte protease inhibitor transcript levels in airway epithelial cells. Am J Physiol 1993; 265: L286–L292.
    • (1993) Am J Physiol , vol.265 , pp. L286-L292
    • Abbinante-Nissen, J.M.1    Simpson, L.G.2    Leikauf, G.D.3
  • 28
    • 0035991313 scopus 로고    scopus 로고
    • Role of secretory leukocyte protease inhibitor in the development of subclinical emphysema
    • Betsuyaku T, Takeyabu K, Tanino M, et al. Role of secretory leukocyte protease inhibitor in the development of subclinical emphysema. Eur Respir J 2002; 19: 1051–1057.
    • (2002) Eur Respir J , vol.19 , pp. 1051-1057
    • Betsuyaku, T.1    Takeyabu, K.2    Tanino, M.3
  • 29
    • 0033428850 scopus 로고    scopus 로고
    • Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha(1)-antitrypsin deficiency (PiZ)
    • Hill AT, Campbell EJ, Bayley DL, et al. Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha(1)-antitrypsin deficiency (PiZ). Am J Respir Crit Care Med 1999; 160: 1968–1975.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1968-1975
    • Hill, A.T.1    Campbell, E.J.2    Bayley, D.L.3
  • 30
    • 60549100921 scopus 로고    scopus 로고
    • Suppression of pulmonary innate host defence in smokers
    • Herr C, Beisswenger C, Hess C, et al. Suppression of pulmonary innate host defence in smokers. Thorax 2009; 64: 144–149.
    • (2009) Thorax , vol.64 , pp. 144-149
    • Herr, C.1    Beisswenger, C.2    Hess, C.3
  • 31
    • 77953519935 scopus 로고    scopus 로고
    • Infection as a comorbidity of COPD
    • Sethi S. Infection as a comorbidity of COPD. Eur Respir J 2010; 35: 1209–1215.
    • (2010) Eur Respir J , vol.35 , pp. 1209-1215
    • Sethi, S.1
  • 32
    • 0041620454 scopus 로고    scopus 로고
    • Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis
    • White AJ, Gompertz S, Bayley DL, et al. Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis. Thorax 2003; 58: 680–685.
    • (2003) Thorax , vol.58 , pp. 680-685
    • White, A.J.1    Gompertz, S.2    Bayley, D.L.3
  • 33
    • 0034018102 scopus 로고    scopus 로고
    • Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations
    • Bhowmik A, Seemungal TA, Sapsford RJ, et al. Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000; 55: 114–120.
    • (2000) Thorax , vol.55 , pp. 114-120
    • Bhowmik, A.1    Seemungal, T.A.2    Sapsford, R.J.3
  • 34
    • 0035153325 scopus 로고    scopus 로고
    • Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD
    • Gompertz S, Bayley DL, Hill SL, et al. Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD. Thorax 2001; 56: 36–41.
    • (2001) Thorax , vol.56 , pp. 36-41
    • Gompertz, S.1    Bayley, D.L.2    Hill, S.L.3
  • 35
    • 84906673705 scopus 로고    scopus 로고
    • The role of the microbiome in exacerbations of chronic lung diseases
    • Dickson RP, Martinez FJ, Huffnagle GB. The role of the microbiome in exacerbations of chronic lung diseases. Lancet 2014; 384: 691–702.
    • (2014) Lancet , vol.384 , pp. 691-702
    • Dickson, R.P.1    Martinez, F.J.2    Huffnagle, G.B.3
  • 36
    • 84922479758 scopus 로고    scopus 로고
    • Host-microorganism interactions in lung diseases
    • Marsland BJ, Gollwitzer ES. Host-microorganism interactions in lung diseases. Nat Rev Immunol 2014; 14: 827–835.
    • (2014) Nat Rev Immunol , vol.14 , pp. 827-835
    • Marsland, B.J.1    Gollwitzer, E.S.2
  • 37
    • 84924565068 scopus 로고    scopus 로고
    • PH modulates the activity and synergism of the airway surface liquid antimicrobials beta-defensin-3 and LL-37
    • Abou Alaiwa MH, Reznikov LR, Gansemer ND, et al. pH modulates the activity and synergism of the airway surface liquid antimicrobials beta-defensin-3 and LL-37. Proc Natl Acad Sci USA 2014; 111: 18703–18708.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 18703-18708
    • Abou Alaiwa, M.H.1    Reznikov, L.R.2    Gansemer, N.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.