Ontology-based vaccine adverse event representation and analysis

Advances in Experimental Medicine and Biology

Volumn 1028, Issue , 2017, Pages 89-103

  Xie, Jiangan ^a,b   He, Yongqun ^b  

^a CHONGQING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adverse event; Flublok; Ontology; Vaccine administration

Indexed keywords

CHI SQUARE TEST; COST EFFECTIVENESS ANALYSIS; HEALTH CARE ORGANIZATION; HOSPITALIZATION; HUMAN; ONTOLOGY DEVELOPMENT; PRIORITY JOURNAL; PROPORTIONAL REPORTING RATIO; SMALLPOX; STANDARDIZATION; STATISTICAL ANALYSIS; VACCINATION;

VACCINE;

DATA INTERPRETATION, STATISTICAL; HUMANS; VACCINES;

EID: 85032357997     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-981-10-6041-0_6     Document Type: Chapter

References (33)

1. Riedel S (2005) Edward Jenner and the history of smallpox and vaccination. Proceedings (Baylor University. Medical Center) 18(1):21
2. Henderson DA (2011) The eradication of smallpox – an overview of the past, present, and future. Vaccine 29:D7–D9
3. Bonanni P (1999) Demographic impact of vaccination: a review. Vaccine 17:S120–S125
4. Haber P et al (2009) Vaccines and Guillain-Barre syndrome. Drug Saf 32(4):309–323
5. Brown EG, Wood L, Wood S (1999) The medical dictionary for regulatory activities (MedDRA). Drug Saf 20(2):109–117
6. NCI. The Common Terminology Criteria for Adverse Events (CTCAE). Available from: http://evs.nci.nih.gov/ftp1/CTCAE/About.html. Access on 7 Oct 2015
7. WHO. The WHO Adverse Reaction Terminology – WHO-ART. Available from: https://www.umc-products.com/graphics/28010.pdf
8. He YQ et al (2014) OAE: the ontology of adverse events. J Biomed Semant 5:29
9. He Y (2016) Ontology-based vaccine and drug adverse event representation and theory-guided systematic causal network analysis toward integrative pharmacovigilance research. Curr Pharmacol Rep:1–16. doi:10.1007/s40495-016-0055-0). In press
10. He Y, et al (2009) VO: vaccine ontology. In The 1st International Conference on Biomedical Ontology (ICBO-2009). Nature Precedings, Buffalo. http://precedings.nature.com/documents/ 3552/version/1
11. Ozgur A et al (2011) Mining of vaccine-associated IFN-gamma gene interaction networks using the vaccine ontology. J Biomed Semant 2(2):S8
12. Lin Y, He Y (2012) Ontology representation and analysis of vaccine formulation and administration and their effects on vaccine immune responses. J Biomed Semant 3(1):17
13. Marcos E, Zhao B, He Y (2013) The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines. J Biomed Semant 4:40
14. Chen RT et al (1994) The vaccine adverse event reporting system (Vaers) (Vol 12, Pg 542, 1994). Vaccine 12(10):960–960
15. Huber VC, McCullers JA (2008) FluBlok, a recombinant influenza vaccine. Curr Opin Mol Ther 10(1):75–85
16. Varricchio F et al (2004) Understanding vaccine safety information from the vaccine adverse event reporting system. Pediatr Infect Dis J 23(4):287–294
17. Sarntivijai S et al (2012) Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines. PLoS One 7(11):e49941
18. Sarntivijai S et al (2016) Linking MedDRA®-coded clinical phenotypes to biological mechanisms by the ontology of adverse events: a pilot study on tyrosine kinase inhibitors. Drug Saf:1–11
19. Evans SJW, Waller PC, Davis S (2001) Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports. Pharmacoepidemiol Drug Saf 10 (6):483–486
20. Banks D et al (2005) Comparing data mining methods on the VAERS database. Pharmacoepidemiol Drug Saf 14(9):601–609
21. Woo EJ et al (2008) Effects of stratification on data mining in the US Vaccine Adverse Event Reporting System (VAERS). Drug Saf 31(8):667–674
22. Pearson K (1900) X. on the criterion that a given system of deviations from the probable in the case of a correlated system of variables is such that it can be reasonably supposed to have arisen from random sampling. Lond, Edinb Dublin Philos Mag J Sci 50(302):157–175
23. Fisher RA (1922) On the interpretation of χ 2 from contingency tables, and the calculation of P. J R Stat Soc 85(1):87–94
24. Yates F (1934) Contingency tables involving small numbers and the χ2 test. Suppl J R Stat Soc 1:217–235
25. Xie J et al (2016) Differential adverse event profiles associated with BCG as a preventive tuberculosis vaccine or therapeutic bladder cancer vaccine identified by comparative ontologybased VAERS and literature meta-analysis. PLoS One 11(10):e0164792
26. Xie J et al (2016) Statistical and ontological analysis of adverse events associated with monovalent and combination vaccines against hepatitis A and B diseases. Sci Rep 6
27. Brown EG (2003) Methods and pitfalls in searching drug safety databases utilising the Medical Dictionary for Regulatory Activities (MedDRA). Drug Saf 26(3):145–158
28. Xiang Z, et al (2011) Ontobee: a linked data server and browser for ontology terms. In the 2nd International Conference on Biomedical Ontologies (ICBO). CEUR Workshop Proceedings, New York
29. Cox MM et al (2015) Safety, efficacy, and immunogenicity of Flublok in the prevention of seasonal influenza in adults. Ther Adv Vaccines 3(4):97–108
30. Poland GA et al (2007) Heterogeneity in vaccine immune response: the role of immunogenetics and the emerging field of vaccinomics. Clin Pharmacol Ther 82(6):653–664
31. Poland GA, Ovsyannikova IG, Jacobson RM (2009) Application of pharmacogenomics to vaccines. Pharmacogenomics 10(5):837–852
32. He Y (2014) Ontology-supported research on vaccine efficacy, safety and integrative biological networks. Expert Rev Vaccines 13(7):825–841
33. Xiang Z et al (2010) OntoFox: web-based support for ontology reuse. BMC Res Notes 3 (1):175