-
1
-
-
84929481480
-
Pembrolizumab for the treatment of non–small-cell lung cancer
-
Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, et al. Pembrolizumab for the treatment of non–small-cell lung cancer. N Engl J Med 2015;372:2018–28.
-
(2015)
N Engl J Med
, vol.372
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
Leighl, N.4
Balmanoukian, A.S.5
Eder, J.P.6
-
2
-
-
85013496342
-
Approvals in 2016: The March of the checkpoint inhibitors
-
Blumenthal GM, Pazdur R. Approvals in 2016: the march of the checkpoint inhibitors. Nat Rev Clin Oncol 2017;14:131–2.
-
(2017)
Nat Rev Clin Oncol
, vol.14
, pp. 131-132
-
-
Blumenthal, G.M.1
Pazdur, R.2
-
3
-
-
84994120928
-
PD-1-PD-L1 immune-checkpoint blockade in B-cell lymphomas
-
Goodman A, Patel SP, Kurzrock R. PD-1-PD-L1 immune-checkpoint blockade in B-cell lymphomas. Nat Rev Clin Oncol 2017;14:203–20.
-
(2017)
Nat Rev Clin Oncol
, vol.14
, pp. 203-220
-
-
Goodman, A.1
Patel, S.P.2
Kurzrock, R.3
-
4
-
-
36748999428
-
Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
-
Downey SG, Klapper JA, Smith FO, Yang JC, Sherry RM, Royal RE, et al. Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade. Clin Cancer Res 2007;13:6681–8.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6681-6688
-
-
Downey, S.G.1
Klapper, J.A.2
Smith, F.O.3
Yang, J.C.4
Sherry, R.M.5
Royal, R.E.6
-
5
-
-
84862859820
-
Safety, activity, and immune correlates of anti–PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti–PD-1 antibody in cancer. N Engl J Med 2012;366:2443–54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
6
-
-
85018847861
-
Hyperprogressive disease is a new pattern of progression in cancer patients treated by anti–PD-1/PD-L1
-
cited 2017 Mar 22
-
Champiat S, Dercle L, Ammari S, Massard C, Hollebecque A, Postel-Vinay S, et al. Hyperprogressive disease is a new pattern of progression in cancer patients treated by anti–PD-1/PD-L1. Clin Cancer Res. 2016[cited 2017 Mar 22]; Available from:http://clincancerres.aacrjournals.org/lookup/doi/ 10.1158/1078-0432.CCR-16-1741
-
(2016)
Clin Cancer Res
-
-
Champiat, S.1
Dercle, L.2
Ammari, S.3
Massard, C.4
Hollebecque, A.5
Postel-Vinay, S.6
-
7
-
-
85026810566
-
Hyper-progressors after immunotherapy: Analysis of genomic alterations associated with accelerated growth rate
-
clincanres.3133.2016
-
Kato S, Goodman AM, Walavalkar V, Barkauskas DA, Sharabi A, Kurzrock R. Hyper-progressors after immunotherapy: analysis of genomic alterations associated with accelerated growth rate. Clin Cancer Res 2017; clincanres.3133.2016.
-
(2017)
Clin Cancer Res
-
-
Kato, S.1
Goodman, A.M.2
Walavalkar, V.3
Barkauskas, D.A.4
Sharabi, A.5
Kurzrock, R.6
-
8
-
-
84946615376
-
Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice
-
Campesato LF, Barroso-Sousa R, Jimenez L, Correa BR, Sabbaga J, Hoff PM, et al. Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice. Oncotarget 2015;6:34221–7.
-
(2015)
Oncotarget
, vol.6
, pp. 34221-34227
-
-
Campesato, L.F.1
Barroso-Sousa, R.2
Jimenez, L.3
Correa, B.R.4
Sabbaga, J.5
Hoff, P.M.6
-
9
-
-
84949009842
-
Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA
-
Lanman RB, Mortimer SA, Zill OA, Sebisanovic D, Lopez R, Blau S, et al. Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA. PLoS ONE 2015;10:e0140712.
-
(2015)
Plos ONE
, vol.10
, pp. e0140712
-
-
Lanman, R.B.1
Mortimer, S.A.2
Zill, O.A.3
Sebisanovic, D.4
Lopez, R.5
Blau, S.6
-
10
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med 2014;371:2189–99.
-
(2014)
N Engl J Med
, vol.371
, pp. 2189-2199
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
Yuan, J.4
Zaretsky, J.M.5
Desrichard, A.6
-
11
-
-
85014030093
-
Tumor mutation load assessed by FoundationOne (FM1) is associated with improved efficacy of atezolizumab (atezo) in patients with advanced NSCLC
-
online
-
Kowanetz M, Zou W, Shames DS, Cummings C, Rizvi N, Spira AI, et al. Tumor mutation load assessed by FoundationOne (FM1) is associated with improved efficacy of atezolizumab (atezo) in patients with advanced NSCLC. Ann of Oncol 2016;27[online].
-
(2016)
Ann of Oncol
, vol.27
-
-
Kowanetz, M.1
Zou, W.2
Shames, D.S.3
Cummings, C.4
Rizvi, N.5
Spira, A.I.6
-
12
-
-
84991204006
-
PD-L1 expression, Cancer Genome Atlas (TCGA) subtype, and mutational load as independent predictors of response to atezolizumab (atezo) in metastatic urothelial carcinoma (mUC; IMvigor210)
-
Rosenberg JE, Petrylak DP, Heijden MSVD, Necchi A, O'Donnell PH, Loriot Y, et al. PD-L1 expression, Cancer Genome Atlas (TCGA) subtype, and mutational load as independent predictors of response to atezolizumab (atezo) in metastatic urothelial carcinoma (mUC; IMvigor210). J Clin Oncol 2016;34. Available from:http://meetinglibrary.asco.org/content/ 165087-176
-
(2016)
J Clin Oncol
, vol.34
-
-
Rosenberg, J.E.1
Petrylak, D.P.2
Heijden, M.S.V.D.3
Necchi, A.4
O'Donnell, P.H.5
Loriot, Y.6
-
13
-
-
14544300998
-
Systematic review of microsatellite instability and colorectal cancer prognosis
-
Popat S, Hubner R, Houlston RS. Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 2005;23: 609–18.
-
(2005)
J Clin Oncol
, vol.23
, pp. 609-618
-
-
Popat, S.1
Hubner, R.2
Houlston, R.S.3
-
14
-
-
84875475811
-
Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
-
Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, et al. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res 2013;73:1733–41.
-
(2013)
Cancer Res
, vol.73
, pp. 1733-1741
-
-
Lyford-Pike, S.1
Peng, S.2
Young, G.D.3
Taube, J.M.4
Westra, W.H.5
Akpeng, B.6
-
15
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science 2015;348:69–74.
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
16
-
-
84928761118
-
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 2015;348:124–8.
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
-
17
-
-
85014834973
-
Genomic analysis of immune cell infiltrates across 11 tumor types
-
Iglesia MD, Parker JS, Hoadley KA, Serody JS, Perou CM, Vincent BG. Genomic analysis of immune cell infiltrates across 11 tumor types. J Natl Cancer Inst 2016;108:djw144.
-
(2016)
J Natl Cancer Inst
, vol.108
, pp. djw144
-
-
Iglesia, M.D.1
Parker, J.S.2
Hoadley, K.A.3
Serody, J.S.4
Perou, C.M.5
Vincent, B.G.6
-
18
-
-
84938717670
-
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma
-
Partlova S, Boucek J, Kloudova K, Lukeŝova E, Zabrodsky M, Grega M, et al. Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma. Oncoimmunology 2015;4:e965570.
-
(2015)
Oncoimmunology
, vol.4
, pp. e965570
-
-
Partlova, S.1
Boucek, J.2
Kloudova, K.3
Lukeŝova, E.4
Zabrodsky, M.5
Grega, M.6
-
19
-
-
84935474357
-
PD-L1 expression as a predictive biomarker in cancer immunotherapy
-
Patel SP, Kurzrock R. PD-L1 expression as a predictive biomarker in cancer immunotherapy. Mol Cancer Ther 2015;14:847–56.
-
(2015)
Mol Cancer Ther
, vol.14
, pp. 847-856
-
-
Patel, S.P.1
Kurzrock, R.2
-
20
-
-
84996551878
-
Next generation predictive biomarkers for immune checkpoint inhibition
-
Khagi Y, Kurzrock R, Patel SP. Next generation predictive biomarkers for immune checkpoint inhibition. Cancer Metastasis Rev 2017;36:179–90.
-
(2017)
Cancer Metastasis Rev
, vol.36
, pp. 179-190
-
-
Khagi, Y.1
Kurzrock, R.2
Patel, S.P.3
-
21
-
-
85015145636
-
High expression of PD-1 ligands is associated with kataegis mutational signature and APOBEC3 alterations
-
Boichard A, Tsigelny IF, Kurzrock R. High expression of PD-1 ligands is associated with kataegis mutational signature and APOBEC3 alterations. Oncoimmunology 2017;e1284719.
-
(2017)
Oncoimmunology
, pp. e1284719
-
-
Boichard, A.1
Tsigelny, I.F.2
Kurzrock, R.3
-
22
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med 2015; 372:2509–20.
-
(2015)
N Engl J Med
, vol.372
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
Bartlett, B.R.4
Kemberling, H.5
Eyring, A.D.6
-
23
-
-
84873096362
-
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
-
Palles C, Cazier J-B, Howarth KM, Domingo E, Jones AM, Broderick P, et al. Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nature Genet 2012;45:136–44.
-
(2012)
Nature Genet
, vol.45
, pp. 136-144
-
-
Palles, C.1
Cazier, J.-B.2
Howarth, K.M.3
Domingo, E.4
Jones, A.M.5
Broderick, P.6
-
24
-
-
84931444036
-
POLE proofreading mutations elicit an antitumor immune response in endometrial cancer
-
van Gool IC, Eggink FA, Freeman-Mills L, Stelloo E, Marchi E, de Bruyn M, et al. POLE proofreading mutations elicit an antitumor immune response in endometrial cancer. Clin Cancer Res 2015;21:3347–55.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 3347-3355
-
-
Van Gool, I.C.1
Eggink, F.A.2
Freeman-Mills, L.3
Stelloo, E.4
Marchi, E.5
De Bruyn, M.6
-
25
-
-
85029473285
-
Tumor cell-free DNA copy number instability predicts therapeutic response to immunotherapy
-
Epub ahead of print
-
Weiss GJ, Beck J, Braun DP, Bornemann-Kolatzki K, Barilla H, Cubello R, et al. Tumor cell-free DNA copy number instability predicts therapeutic response to immunotherapy. Clin Cancer Res 2017; doi: 10.1158/1078-0432.CCR-17-0231. [Epub ahead of print].
-
(2017)
Clin Cancer Res
-
-
Weiss, G.J.1
Beck, J.2
Braun, D.P.3
Bornemann-Kolatzki, K.4
Barilla, H.5
Cubello, R.6
|