IL-17-secreting γδ T cells are completely dependent upon CCR6 for homing to inflamed skin

Journal of Immunology

Volumn 199, Issue 9, 2017, Pages 3129-3136

  Campbell, James J ^a   Ebsworth, Karen ^a   Ertl, Linda S ^a   McMahon, Jeffrey P ^a   Newland, Dale ^a   Wang, Yu ^a   Liu, Shirley ^a   Miao, Zhenhua ^a   Dang, Ton ^a   Zhang, Penglie ^a   Charo, Israel F ^a   Singh, Rajinder ^a   Schall, Thomas J ^a  

^a ChemoCentryx Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCX 2553; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR6; INTERLEUKIN 17; NAVARIXIN; UNCLASSIFIED DRUG; CCR6 PROTEIN, MOUSE; IL23A PROTEIN, MOUSE; INTERLEUKIN 23P19; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DERMATITIS; DRUG BLOOD LEVEL; DRUG EFFICACY; GAMMA DELTA T LYMPHOCYTE; LYMPHOCYTE HOMING; MINIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS; ANIMAL; BAGG ALBINO MOUSE; CELL MOTION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY; SKIN; T LYMPHOCYTE;

ANIMALS; CELL MOVEMENT; INTERLEUKIN-17; INTERLEUKIN-23 SUBUNIT P19; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PSORIASIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, CCR6; SKIN; T-LYMPHOCYTES;

EID: 85032022887     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700826     Document Type: Article

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