메뉴 건너뛰기




Volumn , Issue , 2007, Pages 263-275

Hepatocellular Carcinoma in NAFLD

Author keywords

Cirrhosis; Diabetes; Hepatocellular carcinoma; Nonalcoholic fatty liver disease (NAFLD); Obesity

Indexed keywords


EID: 85031826745     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470987438.ch22     Document Type: Chapter
Times cited : (4)

References (84)
  • 1
    • 0028875908 scopus 로고
    • The natural history of non-alcoholic fatty liver: a follow-up study
    • Teli MR, James OFW, Burt D et al. The natural history of non-alcoholic fatty liver: a follow-up study. Hepatology 1995; 22: 1714-9.
    • (1995) Hepatology , vol.22 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.W.2    Burt, D.3
  • 2
    • 0034116558 scopus 로고    scopus 로고
    • Liver fibrosis in overweight patients
    • Ratziu V, Giral P, Charlotte F et al. Liver fibrosis in overweight patients. Gastroenterology 2000; 118: 1117-23.
    • (2000) Gastroenterology , vol.118 , pp. 1117-1123
    • Ratziu, V.1    Giral, P.2    Charlotte, F.3
  • 3
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with non-alcoholic steatohep- atitis
    • Angulo P, Keach JC, Batts KP et al. Independent predictors of liver fibrosis in patients with non-alcoholic steatohep- atitis. Hepatology 1999; 30: 1356-62.
    • (1999) Hepatology , vol.30 , pp. 1356-1362
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3
  • 4
    • 0025178612 scopus 로고
    • The natural history of non-alcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years
    • Powell EE, Cooksley WGE, Hanson R et al. The natural history of non-alcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 1990; 11: 74-80.
    • (1990) Hepatology , vol.11 , pp. 74-80
    • Powell, E.E.1    Cooksley, W.G.E.2    Hanson, R.3
  • 5
    • 0024336332 scopus 로고
    • Non-alcoholic steatohepatitis: a study of 49 patients
    • Lee RG. Non-alcoholic steatohepatitis: a study of 49 patients. Hum Pathol 1989; 20: 594-8.
    • (1989) Hum Pathol. , vol.20 , pp. 594-598
    • Lee, R.G.1
  • 6
    • 0028070562 scopus 로고
    • Non-alcoholic steatohepatitis: an expanded clinical entity
    • Bacon BR, Farahvash MJ, Janney CG et al. Non-alcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 1994; 107: 1103-9.
    • (1994) Gastroenterology , vol.107 , pp. 1103-1109
    • Bacon, B.R.1    Farahvash, M.J.2    Janney, C.G.3
  • 7
    • 0033019013 scopus 로고    scopus 로고
    • Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease
    • Caldwell SH, Oelsner DH, Iezzoni JC et al. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999; 29: 664-9.
    • (1999) Hepatology , vol.29 , pp. 664-669
    • Caldwell, S.H.1    Oelsner, D.H.2    Iezzoni, J.C.3
  • 8
    • 0033797838 scopus 로고    scopus 로고
    • Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study
    • Poonawala A, Nair SP, Thuluvath PJ. Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study. Hepatology 2000; 32: 689-92.
    • (2000) Hepatology , vol.32 , pp. 689-692
    • Poonawala, A.1    Nair, S.P.2    Thuluvath, P.J.3
  • 9
    • 0036138917 scopus 로고    scopus 로고
    • Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States
    • Nair S, Verma S, Thuluvath PJ. Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States. Hepatology 2002; 35: 105-9.
    • (2002) Hepatology , vol.35 , pp. 105-109
    • Nair, S.1    Verma, S.2    Thuluvath, P.J.3
  • 10
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity
    • Matteoni CA, Younossi ZM, Grämlich T et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 116: 1413-9.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Grämlich, T.3
  • 11
    • 18544365700 scopus 로고    scopus 로고
    • Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis
    • Ratziu V, Bonyhay L, Di Martino V et al. Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis. Hepatology 2002; 35: 1485-93.
    • (2002) Hepatology , vol.35 , pp. 1485-1493
    • Ratziu, V.1    Bonyhay, L.2    Di Martino, V.3
  • 12
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag H, Mason A. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999; 340: 745-50.
    • (1999) N Engl J Med. , vol.340 , pp. 745-750
    • El-Serag, H.1    Mason, A.2
  • 13
    • 0035991455 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
    • Shimada M, Hashimoto E, Taniai M et al. Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. J Hepatol 2002; 37: 154-60.
    • (2002) J Hepatol. , vol.37 , pp. 154-160
    • Shimada, M.1    Hashimoto, E.2    Taniai, M.3
  • 14
    • 0033785224 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis and hepatocellular carcinoma: natural history?
    • Cotrim HP, Parana R, Braga E et al. Non-alcoholic steatohepatitis and hepatocellular carcinoma: natural history? Am J Gastroenterol. 2000; 95: 3018-9.
    • (2000) Am J Gastroenterol. , vol.95 , pp. 3018-3019
    • Cotrim, H.P.1    Parana, R.2    Braga, E.3
  • 15
    • 0035111170 scopus 로고    scopus 로고
    • Hepatocellular carcinoma arising in non-alcoholic steatohepatitis
    • Zen Y, Katayanagi K, Tsuneyama K et al. Hepatocellular carcinoma arising in non-alcoholic steatohepatitis. Pathol Int 2001; 51: 127-31.
    • (2001) Pathol Int. , vol.51 , pp. 127-131
    • Zen, Y.1    Katayanagi, K.2    Tsuneyama, K.3
  • 16
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of non-alcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma
    • Bugianesi E, Leone N, Vanni E et al. Expanding the natural history of non-alcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002; 123: 134-40.
    • (2002) Gastroenterology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3
  • 17
    • 0036894480 scopus 로고    scopus 로고
    • NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States
    • Marrero JA, Fontana RJ, Su GL et al. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 2002; 36: 1349-54.
    • (2002) Hepatology , vol.36 , pp. 1349-1354
    • Marrero, J.A.1    Fontana, R.J.2    Su, G.L.3
  • 18
    • 0029821203 scopus 로고    scopus 로고
    • Excess risk of primary liver cancer in patients with diabetes mellitus
    • Adami HO, Chow WH, Nyren O et al. Excess risk of primary liver cancer in patients with diabetes mellitus. J Natl Cancer Inst 1996; 88: 1472-7.
    • (1996) J Natl Cancer Inst. , vol.88 , pp. 1472-1477
    • Adami, H.O.1    Chow, W.H.2    Nyren, O.3
  • 19
    • 0022968959 scopus 로고
    • Diabetes mellitus and primary hepatocellular carcinoma
    • Lawson DH, Gray JM, McKillop C et al. Diabetes mellitus and primary hepatocellular carcinoma. Q J Med 1986; 61: 945-55.
    • (1986) Q J Med. , vol.61 , pp. 945-955
    • Lawson, D.H.1    Gray, J.M.2    McKillop, C.3
  • 20
    • 0030774675 scopus 로고    scopus 로고
    • Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark
    • Wideroff L, Gridley G, Mellemkjaer L et al. Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark. J Natl Cancer Inst 1997; 89: 1360-5.
    • (1997) J Natl Cancer Inst. , vol.89 , pp. 1360-1365
    • Wideroff, L.1    Gridley, G.2    Mellemkjaer, L.3
  • 21
    • 0023723658 scopus 로고
    • A case-control study of primary hepatocellular carcinoma in Taiwan
    • Lu SN, Lin TM, Chen CJ et al. A case-control study of primary hepatocellular carcinoma in Taiwan. Cancer 1988; 62: 2051-5.
    • (1988) Cancer , vol.62 , pp. 2051-2055
    • Lu, S.N.1    Lin, T.M.2    Chen, C.J.3
  • 22
    • 0026352844 scopus 로고
    • Non-viral risk factors for hepatocellular carcinoma in a low-risk population, the non-Asians of Los Angeles County, California
    • Yu MC, Tong MJ, Govindarajan S et al. Non-viral risk factors for hepatocellular carcinoma in a low-risk population, the non-Asians of Los Angeles County, California. J Natl Cancer Inst 1991; 83: 1820-6.
    • (1991) J Natl Cancer Inst. , vol.83 , pp. 1820-1826
    • Yu, M.C.1    Tong, M.J.2    Govindarajan, S.3
  • 23
    • 0030768876 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of primary liver cancer
    • La Vecchia C, Negri E, Decarli A et al. Diabetes mellitus and the risk of primary liver cancer. Int J Cancer 1997; 73: 204-7.
    • (1997) Int J Cancer , vol.73 , pp. 204-207
    • La Vecchia, C.1    Negri, E.2    Decarli, A.3
  • 24
    • 0036829556 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus
    • Hassan MM, Hwang LY, Hatten CJ et al. Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology 2002; 36: 1206-13.
    • (2002) Hepatology , vol.36 , pp. 1206-1213
    • Hassan, M.M.1    Hwang, L.Y.2    Hatten, C.J.3
  • 25
    • 0034608768 scopus 로고    scopus 로고
    • Role of diabetes mellitus in the etiology of hepatocellular carcinoma
    • Lagiou P, Kuper H, Stuver SO et al. Role of diabetes mellitus in the etiology of hepatocellular carcinoma. J Natl Cancer Inst 2000; 92: 1096-9.
    • (2000) J Natl Cancer Inst. , vol.92 , pp. 1096-1099
    • Lagiou, P.1    Kuper, H.2    Stuver, S.O.3
  • 26
    • 0034881446 scopus 로고    scopus 로고
    • The role of diabetes in hepatocellular carcinoma: a case-control study among United States Veterans
    • El-Serag HB, Richardson PA, Everhart JE. The role of diabetes in hepatocellular carcinoma: a case-control study among United States Veterans. Am J Gastroenterol 2001; 96: 2462-7.
    • (2001) Am J Gastroenterol. , vol.96 , pp. 2462-2467
    • El-Serag, H.B.1    Richardson, P.A.2    Everhart, J.E.3
  • 27
    • 0036288123 scopus 로고    scopus 로고
    • Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?
    • Nair S, Mason A, Eason J et al. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology 2002; 36: 150-5.
    • (2002) Hepatology , vol.36 , pp. 150-155
    • Nair, S.1    Mason, A.2    Eason, J.3
  • 28
    • 0026714915 scopus 로고
    • Alcoholism and cancer risk: a population-based cohort study
    • Adami HO, McLaughlin JK, Hsing AW et al. Alcoholism and cancer risk: a population-based cohort study. Cancer Causes Control 1992; 3: 419-25.
    • (1992) Cancer Causes Control , vol.3 , pp. 419-425
    • Adami, H.O.1    McLaughlin, J.K.2    Hsing, A.W.3
  • 30
    • 0035960427 scopus 로고    scopus 로고
    • Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study
    • Ellervik C, Mandrup-Poulsen T, Nordestgaard BG et al. Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study. Lancet 2001; 358: 1405-9.
    • (2001) Lancet. , vol.358 , pp. 1405-1409
    • Ellervik, C.1    Mandrup-Poulsen, T.2    Nordestgaard, B.G.3
  • 31
    • 0031577947 scopus 로고    scopus 로고
    • Re: excess risk of primary liver cancer in patients with diabetes mellitus
    • Nelson R, Persky V, Davis F et al. Re: excess risk of primary liver cancer in patients with diabetes mellitus. J Natl Cancer Inst 1997; 89: 327-8.
    • (1997) J Natl Cancer Inst. , vol.89 , pp. 327-328
    • Nelson, R.1    Persky, V.2    Davis, F.3
  • 32
    • 0031008177 scopus 로고    scopus 로고
    • Attributable risks for hepatocellular carcinoma in northern Italy
    • Braga C, La Vecchia C, Negri E et al. Attributable risks for hepatocellular carcinoma in northern Italy. Eur J Cancer 1997; 33: 629-34.
    • (1997) Eur J Cancer , vol.33 , pp. 629-634
    • Braga, C.1    La Vecchia, C.2    Negri, E.3
  • 33
    • 0033779703 scopus 로고    scopus 로고
    • Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States
    • Mehta SH, Brancati FL, Sulkowski MS et al. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med 2000; 133: 592-9.
    • (2000) Ann Intern Med. , vol.133 , pp. 592-599
    • Mehta, S.H.1    Brancati, F.L.2    Sulkowski, M.S.3
  • 34
    • 0035146815 scopus 로고    scopus 로고
    • A prospective study of obesity and cancer risk (Sweden)
    • Wolk A, Gridley G, Svensson M et al. A prospective study of obesity and cancer risk (Sweden). Cancer Causes Control 2001; 12: 13-21.
    • (2001) Cancer Causes Control. , vol.12 , pp. 13-21
    • Wolk, A.1    Gridley, G.2    Svensson, M.3
  • 35
    • 0028302476 scopus 로고
    • Obesity and cancer risk: a Danish record-linkage study
    • Moller H, Mellemgaard A, Lindvig K et al. Obesity and cancer risk: a Danish record-linkage study. Eur J Cancer 1994; 30A: 344-50.
    • (1994) Eur J Cancer , vol.30A , pp. 344-350
    • Moller, H.1    Mellemgaard, A.2    Lindvig, K.3
  • 36
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults
    • Calle EE, Rodriguez C, Walker-Thurmond K et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. N Engl J Med 2003; 348: 1625-38.
    • (2003) N Engl J Med. , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3
  • 37
    • 0031979203 scopus 로고    scopus 로고
    • Implications of the hyper- insulinaemia-diabetes-cancer link for preventive efforts
    • Moore MA, Park CB, Tsuda H. Implications of the hyper- insulinaemia-diabetes-cancer link for preventive efforts. Eur J Cancer Prev 1998; 7: 89-107.
    • (1998) Eur J Cancer Prev. , vol.7 , pp. 89-107
    • Moore, M.A.1    Park, C.B.2    Tsuda, H.3
  • 40
    • 0029090318 scopus 로고
    • Insulin resistance, insulin-like growth factor I and breast cancer: a hypothesis
    • Kazer RR. Insulin resistance, insulin-like growth factor I and breast cancer: a hypothesis. IntJ Cancer 1995; 62: 403-6.
    • (1995) IntJ Cancer , vol.62 , pp. 403-406
    • Kazer, R.R.1
  • 41
    • 0029970843 scopus 로고    scopus 로고
    • Nutrition, hormones, and breast cancer: is insulin the missing link?
    • Kaaks R. Nutrition, hormones, and breast cancer: is insulin the missing link?. Cancer Causes Control 1996; 7: 605-25.
    • (1996) Cancer Causes Control , vol.7 , pp. 605-625
    • Kaaks, R.1
  • 42
    • 0027327503 scopus 로고
    • Insulin-like growth factors and binding proteins in colon cancer
    • Singh P, Rubin N. Insulin-like growth factors and binding proteins in colon cancer. Gastroenterology 1993; 105: 1218-37.
    • (1993) Gastroenterology , vol.105 , pp. 1218-1237
    • Singh, P.1    Rubin, N.2
  • 44
    • 0018357649 scopus 로고
    • Hormonal control of rat liver regeneration
    • Leffert HL, Koch KS, Moran T et al. Hormonal control of rat liver regeneration. Gastroenterology 1979; 76: 1470-82.
    • (1979) Gastroenterology , vol.76 , pp. 1470-1482
    • Leffert, H.L.1    Koch, K.S.2    Moran, T.3
  • 45
    • 0019458617 scopus 로고
    • DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: effects of epidermal growth factor, insulin, glucagon, and cyclic-AMP
    • McGowan JA, Strain AJ, Bucher NL. DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: effects of epidermal growth factor, insulin, glucagon, and cyclic-AMP. J Cell Physiol 1981; 108: 353-63.
    • (1981) J Cell Physiol. , vol.108 , pp. 353-363
    • McGowan, J.A.1    Strain, A.J.2    Bucher, N.L.3
  • 46
    • 0026576726 scopus 로고
    • Insulin-like growth factors and cancer
    • Macaulay VM. Insulin-like growth factors and cancer. Br J Cancer 1992; 65: 311-20.
    • (1992) Br J Cancer. , vol.65 , pp. 311-320
    • Macaulay, V.M.1
  • 47
    • 0032579555 scopus 로고    scopus 로고
    • A role for nuclear factor kB in the antiapoptotic function of insulin
    • Bertrand F, Atfi A, Cadoret A et al. A role for nuclear factor kB in the antiapoptotic function of insulin. J Biol Chem 1998; 273: 2931-8.
    • (1998) J Biol Chem. , vol.273 , pp. 2931-2938
    • Bertrand, F.1    Atfi, A.2    Cadoret, A.3
  • 48
    • 0032698132 scopus 로고    scopus 로고
    • Insulin antiapoptotic signalling involves insulin activation of the nuclear factor KB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase
    • Bertrand F, Desbois-Mouthon C, Cadoret A et al. Insulin antiapoptotic signalling involves insulin activation of the nuclear factor KB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase. J Biol Chem 1999; 274: 30596-602.
    • (1999) J Biol Chem. , vol.274 , pp. 30596-30602
    • Bertrand, F.1    Desbois-Mouthon, C.2    Cadoret, A.3
  • 49
    • 0025978339 scopus 로고
    • The effects of alternating dietary restriction and ad libitum feeding of mice on the development of diethylnitrosamine- induced liver tumours and its correlation to insulinaemia
    • Lagopoulos L, Sunahara GI, Wurzner H et al. The effects of alternating dietary restriction and ad libitum feeding of mice on the development of diethylnitrosamine- induced liver tumours and its correlation to insulinaemia. Carcinogenesis 1991; 12: 311-5.
    • (1991) Carcinogenesis , vol.12 , pp. 311-315
    • Lagopoulos, L.1    Sunahara, G.I.2    Wurzner, H.3
  • 50
    • 0031050882 scopus 로고    scopus 로고
    • Hepatocellular neoplasms induced by low-number pancreatic islet transplants in streptozotocin diabetic rats
    • Dombrowski F, Bannasch P, Pfeifer U. Hepatocellular neoplasms induced by low-number pancreatic islet transplants in streptozotocin diabetic rats. Am J Pathol 1997; 150: 1071-87.
    • (1997) Am J Pathol. , vol.150 , pp. 1071-1087
    • Dombrowski, F.1    Bannasch, P.2    Pfeifer, U.3
  • 51
    • 0026605216 scopus 로고
    • Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma
    • Nishiyama M, Wands JR. Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma. Biochem Biophys Res Commun 1992; 183: 280-5.
    • (1992) Biochem Biophys Res Commun. , vol.183 , pp. 280-285
    • Nishiyama, M.1    Wands, J.R.2
  • 52
    • 0030066096 scopus 로고    scopus 로고
    • Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases
    • Ito T, Sasaki Y, Wands JR. Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases. Mol Cell Biol 1996; 16: 943-51.
    • (1996) Mol Cell Biol. , vol.16 , pp. 943-951
    • Ito, T.1    Sasaki, Y.2    Wands, J.R.3
  • 53
    • 0029998031 scopus 로고    scopus 로고
    • A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype
    • Tanaka S, Wands JR. A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype. J Clin Invest 1996; 98: 2100-8.
    • (1996) J Clin Invest. , vol.98 , pp. 2100-2108
    • Tanaka, S.1    Wands, J.R.2
  • 55
    • 0027251602 scopus 로고
    • Insulin deficiency and increased plasma concentration of intact and 32/33 split proinsulin in subjects with impaired glucose tolerance
    • Davies MJ, Rayman G, Gray IP et al. Insulin deficiency and increased plasma concentration of intact and 32/33 split proinsulin in subjects with impaired glucose tolerance. Diabet Med 1993; 10: 313-20.
    • (1993) Diabet Med. , vol.10 , pp. 313-320
    • Davies, M.J.1    Rayman, G.2    Gray, I.P.3
  • 56
    • 0025456944 scopus 로고
    • The possible autocrine-paracrine and endocrine roles of insulin-like growth factors of human tumors
    • Daughaday WH. The possible autocrine-paracrine and endocrine roles of insulin-like growth factors of human tumors. Endocrinology 1990; 127: 1-4.
    • (1990) Endocrinology , vol.127 , pp. 1-4
    • Daughaday, W.H.1
  • 58
    • 0020412933 scopus 로고
    • Rat hepatocyte proliferation is stimulated by insulin-like peptides in defined medium
    • Koch KS, Shapiro P, Skelly H et al. Rat hepatocyte proliferation is stimulated by insulin-like peptides in defined medium. Biochem Biophys Res Commun 1982; 109: 1054-60.
    • (1982) Biochem Biophys Res Commun. , vol.109 , pp. 1054-1060
    • Koch, K.S.1    Shapiro, P.2    Skelly, H.3
  • 59
    • 0030727705 scopus 로고    scopus 로고
    • Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice
    • Dunn SE, Kari FW, French J et al. Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res 1997; 57: 4667-72.
    • (1997) Cancer Res. , vol.57 , pp. 4667-4672
    • Dunn, S.E.1    Kari, F.W.2    French, J.3
  • 60
    • 0028852556 scopus 로고
    • Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis
    • Sell C, Baserga R, Rubin R. Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. Cancer Res 1995; 55: 303-6.
    • (1995) Cancer Res. , vol.55 , pp. 303-306
    • Sell, C.1    Baserga, R.2    Rubin, R.3
  • 61
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice
    • Rogler CE, Yang D, Rossetti L et al. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J Biol Chem 1994; 269: 13779-84.
    • (1994) J Biol Chem. , vol.269 , pp. 13779-13784
    • Rogler, C.E.1    Yang, D.2    Rossetti, L.3
  • 62
    • 0030712864 scopus 로고    scopus 로고
    • Antisense oligodeoxynu- cleotides of IGF-II selectively inhibit growth of human hepatoma cells overproducing IGF-II
    • Lin SB, Hsieh SH, Hsu HL et al. Antisense oligodeoxynu- cleotides of IGF-II selectively inhibit growth of human hepatoma cells overproducing IGF-II. J Biochem (Tokyo) 1997; 122: 717-22.
    • (1997) J Biochem (Tokyo) , vol.122 , pp. 717-722
    • Lin, S.B.1    Hsieh, S.H.2    Hsu, H.L.3
  • 63
    • 0029119731 scopus 로고
    • Insulin-like growth factor-I receptor: its role in cell proliferation, apoptosis, and tumorigenicity
    • Rubin R, Baserga R. Insulin-like growth factor-I receptor: its role in cell proliferation, apoptosis, and tumorigenicity. Lab Invest 1995; 73: 311-31.
    • (1995) Lab Invest. , vol.73 , pp. 311-331
    • Rubin, R.1    Baserga, R.2
  • 64
    • 0028890744 scopus 로고
    • The insulin-like growth factor I receptor: a key to tumor growth?
    • Baserga R. The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res 1995; 55: 249-52.
    • (1995) Cancer Res , vol.55 , pp. 249-252
    • Baserga, R.1
  • 65
    • 0029145296 scopus 로고
    • Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor
    • Miura M, Surmacz E, Burgaud JL et al. Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J Biol Chem 1995; 270: 22639-44.
    • (1995) J Biol Chem. , vol.270 , pp. 22639-22644
    • Miura, M.1    Surmacz, E.2    Burgaud, J.L.3
  • 66
    • 0029096782 scopus 로고
    • Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors
    • Resnicoff M, Burgaud JL, Rotman HL et al. Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors. Cancer Res 1995; 55: 3739-41.
    • (1995) Cancer Res. , vol.55 , pp. 3739-3741
    • Resnicoff, M.1    Burgaud, J.L.2    Rotman, H.L.3
  • 67
    • 0035392939 scopus 로고    scopus 로고
    • Hepatic hyperplasia in non-cirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?
    • Yang S, Lin HZ, Hwang J et al. Hepatic hyperplasia in non-cirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?. Cancer Res 2001; 61: 5016-23.
    • (2001) Cancer Res. , vol.61 , pp. 5016-5023
    • Yang, S.1    Lin, H.Z.2    Hwang, J.3
  • 68
  • 69
    • 0034659814 scopus 로고    scopus 로고
    • Mitochondrial adaptations to obesity-related oxidant stress
    • Yang S, Zhu H, Li Y et al. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 2000; 378: 259-68.
    • (2000) Arch Biochem Biophys. , vol.378 , pp. 259-268
    • Yang, S.1    Zhu, H.2    Li, Y.3
  • 70
    • 0029829455 scopus 로고    scopus 로고
    • Increased hepato- cyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
    • Weltman MD, Farrell GC, Liddle C. Increased hepato- cyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 1996; 111: 1645-53.
    • (1996) Gastroenterology , vol.111 , pp. 1645-1653
    • Weltman, M.D.1    Farrell, G.C.2    Liddle, C.3
  • 71
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine non-alcoholic steatohepatitis
    • Leclercq IA, Farrell GC, Field J, et al. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine non-alcoholic steatohepatitis. J Clin Invest 2000; 105: 1067-75.
    • (2000) J Clin Invest. , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3
  • 72
    • 0031962151 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
    • Weltman MD, Farrell GC, Hall P et al. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology 1998; 27: 128-33.
    • (1998) Hepatology , vol.27 , pp. 128-133
    • Weltman, M.D.1    Farrell, G.C.2    Hall, P.3
  • 73
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities
    • Sanyal AJ, Campbell-Sargent C, Mirshahi F et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001; 120: 1183-92.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3
  • 74
    • 0036676924 scopus 로고    scopus 로고
    • Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
    • Martinez-Chantar ML, Corrales FJ, Martinez-Cruz LA et al. Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. FASEB J 2002; 16: 1292-4.
    • (2002) FASEB J. , vol.16 , pp. 1292-1294
    • Martinez-Chantar, M.L.1    Corrales, F.J.2    Martinez-Cruz, L.A.3
  • 75
    • 0035826898 scopus 로고    scopus 로고
    • Methionine adeno- syltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation
    • Lu SC, Alvarez L, Huang ZZ et al. Methionine adeno- syltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. Proc Natl Acad Sci USA 2001; 98: 5560-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5560-5565
    • Lu, S.C.1    Alvarez, L.2    Huang, Z.Z.3
  • 76
    • 0032054726 scopus 로고    scopus 로고
    • Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells
    • Cai J, Mao Z, Hwang JJ et al. Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells. Cancer Res 1998; 58: 1444-50.
    • (1998) Cancer Res. , vol.58 , pp. 1444-1450
    • Cai, J.1    Mao, Z.2    Hwang, J.J.3
  • 77
    • 0344643016 scopus 로고    scopus 로고
    • Methionine adenosyltransferase II p subunit gene expression provides a proliferative advantage in human hepatoma
    • Martinez-Chantar ML, Garcia-Trevijano ER, Latasa MU et al. Methionine adenosyltransferase II p subunit gene expression provides a proliferative advantage in human hepatoma. Gastroenterology 2003; 124: 940-8.
    • (2003) Gastroenterology , vol.124 , pp. 940-948
    • Martinez-Chantar, M.L.1    Garcia-Trevijano, E.R.2    Latasa, M.U.3
  • 78
    • 0027250370 scopus 로고
    • Fatty-acid metabolism and the pathogenesis of hepatocellular carcinoma: review and hypothesis
    • Ockner RK, Kaikaus RM, Bass NM. Fatty-acid metabolism and the pathogenesis of hepatocellular carcinoma: review and hypothesis. Hepatology 1993; 18: 669-76.
    • (1993) Hepatology , vol.18 , pp. 669-676
    • Ockner, R.K.1    Kaikaus, R.M.2    Bass, N.M.3
  • 79
    • 0032545018 scopus 로고    scopus 로고
    • Mechanism of action of the non-genotoxic peroxisome proliferators: role of the peroxisome proliferator-activator receptor a
    • Gonzalez FJ, Peters JM, Cattley RC. Mechanism of action of the non-genotoxic peroxisome proliferators: role of the peroxisome proliferator-activator receptor a. J Natl Cancer Inst 1998; 90: 1702-9.
    • (1998) J Natl Cancer Inst. , vol.90 , pp. 1702-1709
    • Gonzalez, F.J.1    Peters, J.M.2    Cattley, R.C.3
  • 80
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPARa in the mechanism of action of the non-genotoxic carcinogen and peroxisome proliferator Wy-14,463
    • Peters JM, Cattley RC, Gonzalez FJ. Role of PPARa in the mechanism of action of the non-genotoxic carcinogen and peroxisome proliferator Wy-14,463. Carcinogenesis 1997; 18: 2029-33.
    • (1997) Carcinogenesis , vol.18 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 81
    • 0033516569 scopus 로고    scopus 로고
    • Peroxisomal and mitochondrial fatty acid p-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor a and peroxisomal fatty acyl-CoA oxidase: genotype correlation with fatty liver phenotype
    • Hashimoto T, Fujita T, Usuda N et al. Peroxisomal and mitochondrial fatty acid p-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor a and peroxisomal fatty acyl-CoA oxidase: genotype correlation with fatty liver phenotype. J Biol Chem 1999; 274: 19228-36.
    • (1999) J Biol Chem. , vol.274 , pp. 19228-19236
    • Hashimoto, T.1    Fujita, T.2    Usuda, N.3
  • 82
    • 0033072722 scopus 로고    scopus 로고
    • Three for the price of one knockout: a mouse model of a congenital peroxisomal disorder, steatohep- atitis and hepatocarcinogenesis
    • Bass NM. Three for the price of one knockout: a mouse model of a congenital peroxisomal disorder, steatohep- atitis and hepatocarcinogenesis. Hepatology 1999; 29: 606-8.
    • (1999) Hepatology , vol.29 , pp. 606-608
    • Bass, N.M.1
  • 83
    • 0032546929 scopus 로고    scopus 로고
    • Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase: implications for peroxisome proliferator-activated receptor a natural ligand metabolism
    • Fan CY, Pan J, Usuda N et al. Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase: implications for peroxisome proliferator-activated receptor a natural ligand metabolism. J Biol Chem 1998; 273: 15639-45.
    • (1998) J Biol Chem. , vol.273 , pp. 15639-15645
    • Fan, C.Y.1    Pan, J.2    Usuda, N.3
  • 84
    • 0032941350 scopus 로고    scopus 로고
    • Peroxisome proliferator- activated receptor a: role in rodent liver cancer and species differences
    • Holden PR, Tugwood JD. Peroxisome proliferator- activated receptor a: role in rodent liver cancer and species differences. J Mol Endocrinol 1999; 22: 1-8.
    • (1999) J Mol Endocrinol. , vol.22 , pp. 1-8
    • Holden, P.R.1    Tugwood, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.