메뉴 건너뛰기




Volumn 18, Issue 1, 2018, Pages 95-107

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis

(40)  Schuetz, Philipp a,b   Wirz, Yannick a   Sager, Ramon a   Christ Crain, Mirjam b,c   Stolz, Daiana b,c   Tamm, Michael b,c   Bouadma, Lila e   Luyt, Charles E f   Wolff, Michel e   Chastre, Jean f   Tubach, Florence g   Kristoffersen, Kristina B h   Burkhardt, Olaf i   Welte, Tobias i   Schroeder, Stefan j   Nobre, Vandack k   Wei, Long l   Bucher, Heiner C b,d   Annane, Djillali m   Reinhart, Konrad n   more..


Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PROCALCITONIN; ANTIINFECTIVE AGENT;

EID: 85031330655     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(17)30592-3     Document Type: Article
Times cited : (351)

References (63)
  • 1
    • 85028547658 scopus 로고    scopus 로고
    • FDA press release. FDA clears test to help manage antibiotic treatment for lower respiratory tract infections and sepsis
    • (accessed Oct 2, 2017).
    • US Food and Drug Administration. FDA press release. FDA clears test to help manage antibiotic treatment for lower respiratory tract infections and sepsis. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm543160.htm, Feb 23, 2017 (accessed Oct 2, 2017).
    • (2017)
  • 2
    • 80053173738 scopus 로고    scopus 로고
    • Procalcitonin for diagnosis of infection and guide to antibiotic decisions: past, present and future
    • Schuetz, P, Albrich, W, Mueller, B, Procalcitonin for diagnosis of infection and guide to antibiotic decisions: past, present and future. BMC Med, 9, 2011, 107.
    • (2011) BMC Med , vol.9 , pp. 107
    • Schuetz, P.1    Albrich, W.2    Mueller, B.3
  • 3
    • 67649090473 scopus 로고    scopus 로고
    • Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections—hope for hype?
    • Schuetz, P, Christ-Crain, M, Muller, B, Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections—hope for hype?. Swiss Med Wkly 139 (2009), 318–326.
    • (2009) Swiss Med Wkly , vol.139 , pp. 318-326
    • Schuetz, P.1    Christ-Crain, M.2    Muller, B.3
  • 4
    • 64049119735 scopus 로고    scopus 로고
    • Procalcitonin kinetics within the first days of sepsis: relationship with the appropriateness of antibiotic therapy and the outcome
    • Charles, PE, Tinel, C, Barbar, S, et al. Procalcitonin kinetics within the first days of sepsis: relationship with the appropriateness of antibiotic therapy and the outcome. Crit Care, 13, 2009, R38.
    • (2009) Crit Care , vol.13 , pp. R38
    • Charles, P.E.1    Tinel, C.2    Barbar, S.3
  • 5
    • 85010715713 scopus 로고    scopus 로고
    • Procalcitonin-guided diagnosis and antibiotic stewardship revisited
    • Sager, R, Kutz, A, Mueller, B, Schuetz, P, Procalcitonin-guided diagnosis and antibiotic stewardship revisited. BMC Med, 15, 2017, 15.
    • (2017) BMC Med , vol.15 , pp. 15
    • Sager, R.1    Kutz, A.2    Mueller, B.3    Schuetz, P.4
  • 6
    • 84901468713 scopus 로고    scopus 로고
    • Community-acquired pneumonia
    • Musher, DM, Thorner, AR, Community-acquired pneumonia. N Engl J Med 371 (2014), 1619–1628.
    • (2014) N Engl J Med , vol.371 , pp. 1619-1628
    • Musher, D.M.1    Thorner, A.R.2
  • 7
    • 85020708595 scopus 로고    scopus 로고
    • Antibiotic prescribing for nonbacterial acute upper respiratory infections in elderly persons
    • Silverman, M, Povitz, M, Sontrop, JM, et al. Antibiotic prescribing for nonbacterial acute upper respiratory infections in elderly persons. Ann Intern Med 166 (2017), 765–774.
    • (2017) Ann Intern Med , vol.166 , pp. 765-774
    • Silverman, M.1    Povitz, M.2    Sontrop, J.M.3
  • 9
    • 84961231021 scopus 로고    scopus 로고
    • Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial
    • de Jong, E, van Oers, JA, Beishuizen, A, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial. Lancet Infect Dis 16 (2016), 819–827.
    • (2016) Lancet Infect Dis , vol.16 , pp. 819-827
    • de Jong, E.1    van Oers, J.A.2    Beishuizen, A.3
  • 10
    • 80051637867 scopus 로고    scopus 로고
    • Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms
    • Schuetz, P, Chiappa, V, Briel, M, Greenwald, JL, Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms. Arch Intern Med 171 (2011), 1322–1331.
    • (2011) Arch Intern Med , vol.171 , pp. 1322-1331
    • Schuetz, P.1    Chiappa, V.2    Briel, M.3    Greenwald, J.L.4
  • 11
    • 84876502043 scopus 로고    scopus 로고
    • Can procalcitonin tests aid in identifying bacterial infections associated with influenza pneumonia? A systematic review and meta-analysis
    • Wu, MH, Lin, CC, Huang, SL, et al. Can procalcitonin tests aid in identifying bacterial infections associated with influenza pneumonia? A systematic review and meta-analysis. Influenza Other Respir Viruses 7 (2012), 349–355.
    • (2012) Influenza Other Respir Viruses , vol.7 , pp. 349-355
    • Wu, M.H.1    Lin, C.C.2    Huang, S.L.3
  • 12
    • 84873147056 scopus 로고    scopus 로고
    • The role of procalcitonin in adult patients with community-acquired pneumonia—a systematic review
    • Berg, P, Lindhardt, BO, The role of procalcitonin in adult patients with community-acquired pneumonia—a systematic review. Dan Med J, 59, 2012, A4357.
    • (2012) Dan Med J , vol.59 , pp. A4357
    • Berg, P.1    Lindhardt, B.O.2
  • 13
    • 84998704918 scopus 로고    scopus 로고
    • Effect of sodium selenite administration and procalcitonin-guided therapy on mortality in patients with severe sepsis or septic shock: a randomized clinical trial
    • Bloos, F, Trips, E, Nierhaus, A, et al. Effect of sodium selenite administration and procalcitonin-guided therapy on mortality in patients with severe sepsis or septic shock: a randomized clinical trial. JAMA Intern Med 176 (2016), 1266–1276.
    • (2016) JAMA Intern Med , vol.176 , pp. 1266-1276
    • Bloos, F.1    Trips, E.2    Nierhaus, A.3
  • 14
    • 75949113583 scopus 로고    scopus 로고
    • Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial
    • Bouadma, L, Luyt, CE, Tubach, F, et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet 375 (2010), 463–474.
    • (2010) Lancet , vol.375 , pp. 463-474
    • Bouadma, L.1    Luyt, C.E.2    Tubach, F.3
  • 15
    • 84947030925 scopus 로고    scopus 로고
    • Serum procalcitonin measurement and viral testing to guide antibiotic use for respiratory infections in hospitalized adults: a randomized controlled trial
    • Branche, AR, Walsh, EE, Vargas, R, et al. Serum procalcitonin measurement and viral testing to guide antibiotic use for respiratory infections in hospitalized adults: a randomized controlled trial. J Infect Dis 212 (2015), 1692–1700.
    • (2015) J Infect Dis , vol.212 , pp. 1692-1700
    • Branche, A.R.1    Walsh, E.E.2    Vargas, R.3
  • 16
    • 54049112259 scopus 로고    scopus 로고
    • Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care
    • Briel, M, Schuetz, P, Mueller, B, et al. Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care. Arch Intern Med 168 (2008), 2000–2007.
    • (2008) Arch Intern Med , vol.168 , pp. 2000-2007
    • Briel, M.1    Schuetz, P.2    Mueller, B.3
  • 17
    • 77956563149 scopus 로고    scopus 로고
    • Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection
    • Burkhardt, O, Ewig, S, Haagen, U, et al. Procalcitonin guidance and reduction of antibiotic use in acute respiratory tract infection. Eur Respir J 36 (2010), 601–607.
    • (2010) Eur Respir J , vol.36 , pp. 601-607
    • Burkhardt, O.1    Ewig, S.2    Haagen, U.3
  • 18
    • 1342265610 scopus 로고    scopus 로고
    • Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial
    • Christ-Crain, M, Jaccard-Stolz, D, Bingisser, R, et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 363 (2004), 600–607.
    • (2004) Lancet , vol.363 , pp. 600-607
    • Christ-Crain, M.1    Jaccard-Stolz, D.2    Bingisser, R.3
  • 19
    • 33745471090 scopus 로고    scopus 로고
    • Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial
    • Christ-Crain, M, Stolz, D, Bingisser, R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 174 (2006), 84–93.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 84-93
    • Christ-Crain, M.1    Stolz, D.2    Bingisser, R.3
  • 20
    • 84975842662 scopus 로고    scopus 로고
    • Point-of-care procalcitonin test to reduce antibiotic exposure in patients hospitalized with acute exacerbation of COPD
    • Corti, C, Fally, M, Fabricius-Bjerre, A, et al. Point-of-care procalcitonin test to reduce antibiotic exposure in patients hospitalized with acute exacerbation of COPD. Int J Chron Obstruct Pulmon Dis 11 (2016), 1381–1389.
    • (2016) Int J Chron Obstruct Pulmon Dis , vol.11 , pp. 1381-1389
    • Corti, C.1    Fally, M.2    Fabricius-Bjerre, A.3
  • 21
    • 84879187600 scopus 로고    scopus 로고
    • Clinical and economic impact of procalcitonin to shorten antimicrobial therapy in septic patients with proven bacterial infection in an intensive care setting
    • Deliberato, RO, Marra, AR, Sanches, PR, et al. Clinical and economic impact of procalcitonin to shorten antimicrobial therapy in septic patients with proven bacterial infection in an intensive care setting. Diagn Microbiol Infect Dis 76 (2013), 266–271.
    • (2013) Diagn Microbiol Infect Dis , vol.76 , pp. 266-271
    • Deliberato, R.O.1    Marra, A.R.2    Sanches, P.R.3
  • 22
    • 67650917117 scopus 로고    scopus 로고
    • Procalcitonin to guide duration of antibiotic therapy in intensive care patients: a randomized prospective controlled trial
    • Hochreiter, M, Kohler, T, Schweiger, AM, et al. Procalcitonin to guide duration of antibiotic therapy in intensive care patients: a randomized prospective controlled trial. Crit Care, 13, 2009, R83.
    • (2009) Crit Care , vol.13 , pp. R83
    • Hochreiter, M.1    Kohler, T.2    Schweiger, A.M.3
  • 23
    • 65949114287 scopus 로고    scopus 로고
    • Antibiotic treatment interruption of suspected lower respiratory tract infections based on a single procalcitonin measurement at hospital admission—a randomized trial
    • Kristoffersen, KB, Sogaard, OS, Wejse, C, et al. Antibiotic treatment interruption of suspected lower respiratory tract infections based on a single procalcitonin measurement at hospital admission—a randomized trial. Clin Microbiol Infect 15 (2009), 481–487.
    • (2009) Clin Microbiol Infect , vol.15 , pp. 481-487
    • Kristoffersen, K.B.1    Sogaard, O.S.2    Wejse, C.3
  • 24
    • 84864199718 scopus 로고    scopus 로고
    • Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients
    • Layios, N, Lambermont, B, Canivet, JL, et al. Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients. Crit Care Med 40 (2012), 2304–2309.
    • (2012) Crit Care Med , vol.40 , pp. 2304-2309
    • Layios, N.1    Lambermont, B.2    Canivet, J.L.3
  • 25
    • 79959875641 scopus 로고    scopus 로고
    • Procalcitonin guidance for reduction of antibiotic use in low-risk outpatients with community-acquired pneumonia
    • Long, W, Deng, X, Zhang, Y, Lu, G, Xie, J, Tang, J, Procalcitonin guidance for reduction of antibiotic use in low-risk outpatients with community-acquired pneumonia. Respirology 16 (2011), 819–824.
    • (2011) Respirology , vol.16 , pp. 819-824
    • Long, W.1    Deng, X.2    Zhang, Y.3    Lu, G.4    Xie, J.5    Tang, J.6
  • 26
    • 70349565388 scopus 로고    scopus 로고
    • The value of serum procalcitonin in treatment of community acquired pneumonia in outpatient
    • (in Chinese).
    • Long, W, Deng, XQ, Tang, JG, et al. The value of serum procalcitonin in treatment of community acquired pneumonia in outpatient. Chin J Intern Med 48 (2009), 216–219 (in Chinese).
    • (2009) Chin J Intern Med , vol.48 , pp. 216-219
    • Long, W.1    Deng, X.Q.2    Tang, J.G.3
  • 27
    • 84908510501 scopus 로고    scopus 로고
    • Procalcitonin guidance for reduction of antibiotic use in patients hospitalized with severe acute exacerbations of asthma: a randomized controlled study with 12-month follow-up
    • Long, W, Li, LJ, Huang, GZ, et al. Procalcitonin guidance for reduction of antibiotic use in patients hospitalized with severe acute exacerbations of asthma: a randomized controlled study with 12-month follow-up. Crit Care, 18, 2014, 471.
    • (2014) Crit Care , vol.18 , pp. 471
    • Long, W.1    Li, L.J.2    Huang, G.Z.3
  • 28
    • 84922686189 scopus 로고    scopus 로고
    • Procalcitonin-based therapeutic strategy to reduce antibiotic use in patients after cardiac surgery: a randomized controlled trial
    • Maravić-Stojković, V, Lausević-Vuk, L, Jović, M, Ranković, A, Borzanović, M, Marinković, J, Procalcitonin-based therapeutic strategy to reduce antibiotic use in patients after cardiac surgery: a randomized controlled trial. Srp Arh Celok Lek 139 (2011), 736–742.
    • (2011) Srp Arh Celok Lek , vol.139 , pp. 736-742
    • Maravić-Stojković, V.1    Lausević-Vuk, L.2    Jović, M.3    Ranković, A.4    Borzanović, M.5    Marinković, J.6
  • 29
    • 40649087642 scopus 로고    scopus 로고
    • Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial
    • Nobre, V, Harbarth, S, Graf, JD, Rohner, P, Pugin, J, Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial. Am J Respir Crit Care Med 177 (2008), 498–505.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 498-505
    • Nobre, V.1    Harbarth, S.2    Graf, J.D.3    Rohner, P.4    Pugin, J.5
  • 30
    • 84884908111 scopus 로고    scopus 로고
    • Procalcitonin versus C-reactive protein for guiding antibiotic therapy in sepsis: a randomized trial
    • Oliveira, CF, Botoni, FA, Oliveira, CR, et al. Procalcitonin versus C-reactive protein for guiding antibiotic therapy in sepsis: a randomized trial. Crit Care Med 41 (2013), 2336–2343.
    • (2013) Crit Care Med , vol.41 , pp. 2336-2343
    • Oliveira, C.F.1    Botoni, F.A.2    Oliveira, C.R.3
  • 31
    • 59449093757 scopus 로고    scopus 로고
    • Procalcitonin (PCT)-guided algorithm reduces length of antibiotic treatment in surgical intensive care patients with severe sepsis: results of a prospective randomized study
    • Schroeder, S, Hochreiter, M, Koehler, T, et al. Procalcitonin (PCT)-guided algorithm reduces length of antibiotic treatment in surgical intensive care patients with severe sepsis: results of a prospective randomized study. Langenbecks Arch Surg 394 (2009), 221–226.
    • (2009) Langenbecks Arch Surg , vol.394 , pp. 221-226
    • Schroeder, S.1    Hochreiter, M.2    Koehler, T.3
  • 32
    • 70149088214 scopus 로고    scopus 로고
    • Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial
    • Schuetz, P, Christ-Crain, M, Thomann, R, et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA 302 (2009), 1059–1066.
    • (2009) JAMA , vol.302 , pp. 1059-1066
    • Schuetz, P.1    Christ-Crain, M.2    Thomann, R.3
  • 33
    • 84925366157 scopus 로고    scopus 로고
    • Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial
    • Shehabi, Y, Sterba, M, Garrett, PM, et al. Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial. Am J Respir Crit Care Med 190 (2014), 1102–1110.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 1102-1110
    • Shehabi, Y.1    Sterba, M.2    Garrett, P.M.3
  • 34
    • 33846311358 scopus 로고    scopus 로고
    • Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy
    • Stolz, D, Christ-Crain, M, Bingisser, R, et al. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest 131 (2007), 9–19.
    • (2007) Chest , vol.131 , pp. 9-19
    • Stolz, D.1    Christ-Crain, M.2    Bingisser, R.3
  • 35
    • 73249128024 scopus 로고    scopus 로고
    • Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study
    • Stolz, D, Smyrnios, N, Eggimann, P, et al. Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study. Eur Respir J 34 (2009), 1364–1375.
    • (2009) Eur Respir J , vol.34 , pp. 1364-1375
    • Stolz, D.1    Smyrnios, N.2    Eggimann, P.3
  • 36
    • 84924347524 scopus 로고    scopus 로고
    • Antibiotic treatment of severe exacerbations of chronic obstructive pulmonary disease with procalcitonin: a randomized noninferiority trial
    • Verduri, A, Luppi, F, D'Amico, R, et al. Antibiotic treatment of severe exacerbations of chronic obstructive pulmonary disease with procalcitonin: a randomized noninferiority trial. PLoS One, 10, 2015, e0118241.
    • (2015) PLoS One , vol.10 , pp. e0118241
    • Verduri, A.1    Luppi, F.2    D'Amico, R.3
  • 37
    • 84969851012 scopus 로고    scopus 로고
    • Acute exacerbations of chronic obstructive pulmonary disease with low serum procalcitonin values do not benefit from antibiotic treatment: a prospective randomized controlled trial
    • Wang, JX, Zhang, SM, Li, XH, Zhang, Y, Xu, ZY, Cao, B, Acute exacerbations of chronic obstructive pulmonary disease with low serum procalcitonin values do not benefit from antibiotic treatment: a prospective randomized controlled trial. Int J Infect Dis 48 (2016), 40–45.
    • (2016) Int J Infect Dis , vol.48 , pp. 40-45
    • Wang, J.X.1    Zhang, S.M.2    Li, X.H.3    Zhang, Y.4    Xu, Z.Y.5    Cao, B.6
  • 38
    • 55049135622 scopus 로고    scopus 로고
    • Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections (protocol)
    • CD007498.
    • Schuetz, P, Briel, M, Christ-Crain, M, et al. Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections (protocol). Cochrane Database Syst Rev, 4, 2008 CD007498.
    • (2008) Cochrane Database Syst Rev , vol.4
    • Schuetz, P.1    Briel, M.2    Christ-Crain, M.3
  • 39
    • 84873044315 scopus 로고    scopus 로고
    • Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
    • CD007498.
    • Schuetz, P, Muller, B, Christ-Crain, M, et al. Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database Syst Rev, 9, 2012 CD007498.
    • (2012) Cochrane Database Syst Rev , vol.9
    • Schuetz, P.1    Muller, B.2    Christ-Crain, M.3
  • 40
    • 84928753669 scopus 로고    scopus 로고
    • Preferred Reporting Items for Systematic Review and Meta-Analyses of individual participant data: the PRISMA-IPD Statement
    • Stewart, LA, Clarke, M, Rovers, M, et al. Preferred Reporting Items for Systematic Review and Meta-Analyses of individual participant data: the PRISMA-IPD Statement. JAMA 313 (2015), 1657–1665.
    • (2015) JAMA , vol.313 , pp. 1657-1665
    • Stewart, L.A.1    Clarke, M.2    Rovers, M.3
  • 41
    • 84872011968 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
    • Liberati, A, Altman, DG, Tetzlaff, J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62 (2009), e1–e34.
    • (2009) J Clin Epidemiol , vol.62 , pp. e1-e34
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3
  • 42
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    • Guyatt, GH, Oxman, AD, Vist, GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336 (2008), 924–926.
    • (2008) BMJ , vol.336 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3
  • 43
    • 0035183210 scopus 로고    scopus 로고
    • Multilevel models for meta-analysis, and their application to absolute risk differences
    • Thompson, SG, Turner, RM, Warn, DE, Multilevel models for meta-analysis, and their application to absolute risk differences. Stat Methods Med Res 10 (2001), 375–392.
    • (2001) Stat Methods Med Res , vol.10 , pp. 375-392
    • Thompson, S.G.1    Turner, R.M.2    Warn, D.E.3
  • 44
    • 0034736559 scopus 로고    scopus 로고
    • A multilevel model framework for meta-analysis of clinical trials with binary outcomes
    • Turner, RM, Omar, RZ, Yang, M, Goldstein, H, Thompson, SG, A multilevel model framework for meta-analysis of clinical trials with binary outcomes. Stat Med 19 (2000), 3417–3432.
    • (2000) Stat Med , vol.19 , pp. 3417-3432
    • Turner, R.M.1    Omar, R.Z.2    Yang, M.3    Goldstein, H.4    Thompson, S.G.5
  • 46
    • 39049085847 scopus 로고    scopus 로고
    • Acute lower respiratory tract infection
    • Mizgerd, JP, Acute lower respiratory tract infection. N Engl J Med 358 (2008), 716–727.
    • (2008) N Engl J Med , vol.358 , pp. 716-727
    • Mizgerd, J.P.1
  • 47
    • 0030785447 scopus 로고    scopus 로고
    • Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians
    • Gonzales, R, Steiner, JF, Sande, MA, Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians. JAMA 278 (1997), 901–904.
    • (1997) JAMA , vol.278 , pp. 901-904
    • Gonzales, R.1    Steiner, J.F.2    Sande, M.A.3
  • 48
    • 63249115759 scopus 로고    scopus 로고
    • Antimicrobial stewardship in the intensive care unit: advances and obstacles
    • Lawrence, KL, Kollef, MH, Antimicrobial stewardship in the intensive care unit: advances and obstacles. Am J Respir Crit Care Med 179 (2009), 434–438.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 434-438
    • Lawrence, K.L.1    Kollef, M.H.2
  • 49
    • 84926344321 scopus 로고    scopus 로고
    • Prognostic value of procalcitonin in respiratory tract infections across clinical settings
    • Kutz, A, Briel, M, Christ-Crain, M, et al. Prognostic value of procalcitonin in respiratory tract infections across clinical settings. Crit Care, 19, 2015, 74.
    • (2015) Crit Care , vol.19 , pp. 74
    • Kutz, A.1    Briel, M.2    Christ-Crain, M.3
  • 50
    • 84945971939 scopus 로고    scopus 로고
    • Biomarkers from distinct biological pathways improve early risk stratification in medical emergency patients: the multinational, prospective, observational TRIAGE study
    • Schuetz, P, Hausfater, P, Amin, D, et al. Biomarkers from distinct biological pathways improve early risk stratification in medical emergency patients: the multinational, prospective, observational TRIAGE study. Crit Care, 19, 2015, 377.
    • (2015) Crit Care , vol.19 , pp. 377
    • Schuetz, P.1    Hausfater, P.2    Amin, D.3
  • 51
    • 3943108189 scopus 로고    scopus 로고
    • Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes
    • Linscheid, P, Seboek, D, Schaer, DJ, Zulewski, H, Keller, U, Muller, B, Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes. Crit Care Med 32 (2004), 1715–1721.
    • (2004) Crit Care Med , vol.32 , pp. 1715-1721
    • Linscheid, P.1    Seboek, D.2    Schaer, D.J.3    Zulewski, H.4    Keller, U.5    Muller, B.6
  • 52
    • 25444454875 scopus 로고    scopus 로고
    • Procalcitonin in bacterial infections—hype, hope, more or less?
    • Christ-Crain, M, Muller, B, Procalcitonin in bacterial infections—hype, hope, more or less?. Swiss Med Wkly 135 (2005), 451–460.
    • (2005) Swiss Med Wkly , vol.135 , pp. 451-460
    • Christ-Crain, M.1    Muller, B.2
  • 53
    • 38449105578 scopus 로고    scopus 로고
    • Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators
    • Christ-Crain, M, Muller, B, Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators. Eur Respir J 30 (2007), 556–573.
    • (2007) Eur Respir J , vol.30 , pp. 556-573
    • Christ-Crain, M.1    Muller, B.2
  • 54
    • 18844427583 scopus 로고    scopus 로고
    • Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue
    • Linscheid, P, Seboek, D, Zulewski, H, Keller, U, Muller, B, Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue. Endocrinology 146 (2005), 2699–2708.
    • (2005) Endocrinology , vol.146 , pp. 2699-2708
    • Linscheid, P.1    Seboek, D.2    Zulewski, H.3    Keller, U.4    Muller, B.5
  • 55
    • 84876708502 scopus 로고    scopus 로고
    • Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis
    • Wacker, C, Prkno, A, Brunkhorst, FM, Schlattmann, P, Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. Lancet Infect Dis 13 (2013), 426–435.
    • (2013) Lancet Infect Dis , vol.13 , pp. 426-435
    • Wacker, C.1    Prkno, A.2    Brunkhorst, F.M.3    Schlattmann, P.4
  • 56
    • 77952273695 scopus 로고    scopus 로고
    • Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial
    • Muller, F, Christ-Crain, M, Bregenzer, T, et al. Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial. Chest 138 (2010), 121–129.
    • (2010) Chest , vol.138 , pp. 121-129
    • Muller, F.1    Christ-Crain, M.2    Bregenzer, T.3
  • 57
    • 85014176195 scopus 로고    scopus 로고
    • Serial procalcitonin predicts mortality in severe sepsis patients: results from the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study
    • Schuetz, P, Birkhahn, R, Sherwin, R, et al. Serial procalcitonin predicts mortality in severe sepsis patients: results from the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. Crit Care Med 45 (2017), 781–789.
    • (2017) Crit Care Med , vol.45 , pp. 781-789
    • Schuetz, P.1    Birkhahn, R.2    Sherwin, R.3
  • 58
    • 70349895519 scopus 로고    scopus 로고
    • Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship
    • Roberts, RR, Hota, B, Ahmad, I, et al. Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship. Clin Infect Dis 49 (2009), 1175–1184.
    • (2009) Clin Infect Dis , vol.49 , pp. 1175-1184
    • Roberts, R.R.1    Hota, B.2    Ahmad, I.3
  • 59
    • 77449160108 scopus 로고    scopus 로고
    • Adverse drug events among hospitalized Medicare patients: epidemiology and national estimates from a new approach to surveillance
    • Classen, DC, Jaser, L, Budnitz, DS, Adverse drug events among hospitalized Medicare patients: epidemiology and national estimates from a new approach to surveillance. Jt Comm J Qual Patient Saf 36 (2010), 12–21.
    • (2010) Jt Comm J Qual Patient Saf , vol.36 , pp. 12-21
    • Classen, D.C.1    Jaser, L.2    Budnitz, D.S.3
  • 60
    • 84891026537 scopus 로고    scopus 로고
    • De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock
    • Garnacho-Montero, J, Gutierrez-Pizarraya, A, Escoresca-Ortega, A, et al. De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med 40 (2014), 32–40.
    • (2014) Intensive Care Med , vol.40 , pp. 32-40
    • Garnacho-Montero, J.1    Gutierrez-Pizarraya, A.2    Escoresca-Ortega, A.3
  • 61
    • 84891033316 scopus 로고    scopus 로고
    • Biomarker-guided de-escalation of empirical therapy is associated with lower risk for adverse outcomes
    • Schuetz, P, Mueller, B, Biomarker-guided de-escalation of empirical therapy is associated with lower risk for adverse outcomes. Intensive Care Med, 40, 2014, 141.
    • (2014) Intensive Care Med , vol.40 , pp. 141
    • Schuetz, P.1    Mueller, B.2
  • 62
    • 84962019138 scopus 로고    scopus 로고
    • Infection biomarkers in primary care patients with acute respiratory tract infections-comparison of procalcitonin and C-reactive protein
    • Meili, M, Kutz, A, Briel, M, et al. Infection biomarkers in primary care patients with acute respiratory tract infections-comparison of procalcitonin and C-reactive protein. BMC Pulm Med, 16, 2016, 43.
    • (2016) BMC Pulm Med , vol.16 , pp. 43
    • Meili, M.1    Kutz, A.2    Briel, M.3
  • 63
    • 84941005051 scopus 로고    scopus 로고
    • Management of patients with respiratory infections in primary care: procalcitonin, C-reactive protein or both?
    • Meili, M, Muller, B, Kulkarni, P, Schutz, P, Management of patients with respiratory infections in primary care: procalcitonin, C-reactive protein or both?. Expert Rev Respir Med 9 (2015), 587–601.
    • (2015) Expert Rev Respir Med , vol.9 , pp. 587-601
    • Meili, M.1    Muller, B.2    Kulkarni, P.3    Schutz, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.