The biomarkers neuron-specific enolase and S100b measured the day following admission for severe accidental hypothermia have high predictive values for poor outcome

Resuscitation

Volumn 121, Issue , 2017, Pages 49-53

  Wiberg, Sebastian ^a,b   Kjaergaard, Jesper ^a   Kjærgaard, Benedict ^b,c   Møller, Bjarne ^b   Nørnberg, Bo ^b   Sørensen, Anne Marie ^a   Hassager, Christian ^a,d   Wanscher, Michael ^a  

^a Mental Health Center Glostrup   (Denmark)

^b Danish Armed Forces   (Denmark)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Accidental hypothermia; Cardiac arrest; Neuron specific enolase; Prognostication; S100b

Indexed keywords

BIOLOGICAL MARKER; NEURON SPECIFIC ENOLASE; PROTEIN S100B; ENOLASE; SEA WATER;

ACCIDENTAL HYPOTHERMIA; ADOLESCENT; ADULT; AGED; AREA UNDER THE CURVE; ARTERIAL GAS; ARTICLE; BLOOD ANALYSIS; BRAIN FUNCTION; CEREBRAL PERFORMANCE CATEGORY SCORE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORE TEMPERATURE; DISEASE SEVERITY; ENZYME BLOOD LEVEL; EXTRACORPOREAL CIRCULATION; EXTRACORPOREAL OXYGENATION; FEMALE; FOLLOW UP; HEART ARREST; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; MALE; MIDDLE AGED; MORTALITY; NEUROLOGIC DISEASE ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; RESUSCITATION; SCORING SYSTEM; SEDATION; SURVIVAL PREDICTION; SURVIVOR; THERMOTHERAPY; UNCONSCIOUSNESS; WAKEFULNESS; WARMING; YOUNG ADULT; BLOOD; GLASGOW COMA SCALE; HYPOTHERMIA; OUT OF HOSPITAL CARDIAC ARREST; PROCEDURES;

ADULT; AGED; BIOMARKERS; CARDIOPULMONARY RESUSCITATION; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; GLASGOW COMA SCALE; HUMANS; HYPOTHERMIA; MALE; MIDDLE AGED; OUT-OF-HOSPITAL CARDIAC ARREST; PHOSPHOPYRUVATE HYDRATASE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REWARMING; ROC CURVE; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; SEAWATER; YOUNG ADULT;

EID: 85031008080     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2017.10.006     Document Type: Article

References (20)

1. van der Ploeg, G.-J., Goslings, J.C., Walpoth, B.H., JJLM, Bierens, Accidental hypothermia: rewarming treatments, complications and outcomes from one university medical centre. Resuscitation 81:11 (2010), 1550–1555, 10.1016/j.resuscitation.2010.05.023.
2. Champigneulle, B., Bellenfant-Zegdi, F., Follin, A., et al. Extracorporeal life support (ECLS) for refractory cardiac arrest after drowning: an 11-year experience. Resuscitation 88 (2015), 126–131, 10.1016/j.resuscitation.2014.11.023.
3. Weuster, M., Haneya, A., Panholzer, B., et al. The use of extracorporeal membrane oxygenation systems in severe accidental hypothermia after drowning. a centre experience. ASAIO J, 2015, 1–6, 10.1097/mat.0000000000000312.
4. Truhlář, A., Deakin, C.D., Soar, J., et al. European resuscitation council guidelines for resuscitation 2015: section 4. cardiac arrest in special circumstances. Resuscitation 95 (2015), 148–201, 10.1016/j.resuscitation.2015.07.017.
5. Durrer, B., Brugger, H., Syme, D., The medical on-site treatment of hypothermia* ICAR-MEDCOM recommendation. High Altitude Med Biol 4:1 (2003), 99–103.
6. Schaller, M.-D., Fischer, A.P., Perret, C.H., Hyperkalemia. JAMA 264:14 (1990), 1842–1845.
7. Paal, P., Gordon Les, Strapazzon, G., et al. Accidental hypothermia—an update. Scand J Trauma Resuscitation Emerg Med, 2016, 1–20, 10.1186/s13049-016-0303-7.
8. Stammet, P., Collignon, O., Hassager, C., et al. Neuron-specific enolase as a predictor of death or poor neurological outcome after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C. J Am Coll Cardiol 65:19 (2015), 2104–2114, 10.1016/j.jacc.2015.03.538.
9. Wiberg, S., Hassager, C., Stammet, P., et al. Single versus serial measurements of neuron-specific enolase and prediction of poor neurological outcome in persistently unconscious patients after out-of-hospital cardiac arrest– a TTM-trial substudy. Legriel, S., (eds.) PLoS One, 12(1), 2017, e0168814–e0168894, 10.1371/journal.pone.0168894.
10. Callaway, C.W., Donnino, M.W., Fink, E., Part 8. Post–Cardiac Arrest Care, 2015, 1–19, 10.1161/CIR.0000000000000262.
11. Nolan, J.P., Soar, J., Cariou, A., et al. European resuscitation council and European society of intensive care medicine guidelines for post-resuscitation care 2015: section 5 of the European resuscitation council guidelines for resuscitation. Resuscitation 2015:95 (2015), 202–222, 10.1016/j.resuscitation.2015.07.018.
12. Chabok, S.Y., Moghadam, A.D., Saneei, Z., Amlashi, F.G., Leili, E.K., Amiri, Z.M., Neuron-specific enolase and S100BB as outcome predictors in severe diffuse axonal injury. J Trauma and Acute Care Surg 72:6 (2012), 1654–1657, 10.1097/TA.0b013e318246887e.
13. Oda, Y., Tsuruta, R., Fujita, M., et al. Prediction of the neurological outcome with intrathecal high mobility group Box 1 and S100 B in cardiac arrest victims: a pilot study. Resuscitation 83:8 (2012), 1006–1012, 10.1016/j.resuscitation.2012.01.030.
14. Jennett, B., Bond, M., Assessment of outcome after severe brain damage. Lancet, 1975, 1–5.
15. Tiainen, M., Roine, R.O., Pettilä, V., Takkunen, O., Serum neuron-specific enolase and S-100äB protein in cardiac arrest patients treated with hypothermia. Stroke 34:12 (2003), 2881–2886, 10.1161/01.STR.0000103320.90706.35.
16. Zandbergen, E.G.J., Hijdra, A., Prediction of poor outcome within the first 3 days of postanoxic coma. Neurology, 2005, 1–7.
17. Rundgren, M., Karlsson, T., Nielsen, N., Neuron specific enolase and S-100 B as predictors of outcome after cardiac arrest and induced hypothermia. Resuscitation 80:7 (2016), 784–789.
18. Nielsen, N., Wetterslev, J., Cronberg, T., et al. Targeted temperature management at 33 °C versus 36 °C after cardiac arrest. N Engl J Med 369:23 (2013), 2197–2206, 10.1056/NEJMoa1310519.
19. Bergman, R., Braber, A., Adriaanse, M.A., van Vugt, R., Tjan, D.H., van Zanten, A.R., Haemodynamic consequences of mild therapeutic hypothermia after cardiac arrest. Eur J Anaesthesiol 27:4 (2010), 383–387, 10.1097/EJA.0b013e3283333a7d.
20. Johnsson, P., Blomquist, S., Lürhs, C., Neuron-Specific Enolase Increases in Plasma During and Immediately After Extracorporeal Circulation. 2000, 1–5.