Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells

Cell Stem Cell

Volumn 21, Issue 4, 2017, Pages 472-488.e10

  Jacob, Anjali ^a,b   Morley, Michael ^c   Hawkins, Finn ^a,b   McCauley, Katherine B ^a,b   Jean, J C ^a,b   Heins, Hillary ^d   Na, Cheng Lun ^f   Weaver, Timothy E ^f   Vedaie, Marall ^a,b   Hurley, Killian ^a,b   Hinds, Anne ^b   Russo, Scott J ^c   Kook, Seunghyi ^e   Zacharias, William ^c   Ochs, Matthias ^g   Traber, Katrina ^b   Quinton, Lee J ^b   Crane, Ana ^h   Davis, Brian R ^h   White, Frances V ^d   Wambach, Jennifer ^d   Whitsett, Jeffrey A ^f   Cole, F Sessions ^d   Morrisey, Edward E ^c   Guttentag, Susan H ^e   Beers, Michael F ^c   Kotton, Darrell N ^a,b   more..

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

^f CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

alveolar epithelial cell; CRISPR; development; disease modeling; embryonic stem cells; gene editing; human induced pluripotent stem cells; lung; surfactant; surfactant protein B

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AQUAPORIN 5; PODOPLANIN; SURFACTANT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; UNCLASSIFIED DRUG; HOMEOBOX PROTEIN NKX 2.1; LUNG SURFACTANT; NKX2-1 PROTEIN, HUMAN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; EMBRYO; FETUS LUNG; GENE EDITING; GENETIC BACKGROUND; HUMAN; HUMAN CELL; IN VITRO STUDY; LAMELLAR BODY; LUNG ALVEOLUS CELL TYPE 2; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIMORDIUM; PRIORITY JOURNAL; SKIN FIBROBLAST; STEM CELL SELF-RENEWAL; TISSUE REGENERATION; WNT SIGNALING; BIOLOGICAL MODEL; CELL LINE; CELL PROLIFERATION; CELL SELF-RENEWAL; CELL SEPARATION; CYTOLOGY; EPITHELIUM CELL; GENE EXPRESSION PROFILING; LUNG ALVEOLUS; LUNG DISEASE; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; REPORTER GENE; TIME FACTOR; ULTRASTRUCTURE;

BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SELF RENEWAL; CELL SEPARATION; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENES, REPORTER; HUMANS; LUNG DISEASES; MODELS, BIOLOGICAL; PLURIPOTENT STEM CELLS; PULMONARY ALVEOLI; PULMONARY SURFACTANTS; THYROID NUCLEAR FACTOR 1; TIME FACTORS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 85030716451     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2017.08.014     Document Type: Article

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