M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1

Cell Reports

Volumn 21, Issue 1, 2017, Pages 126-140

  Rajaram, Murugesan V S ^a   Arnett, Eusondia ^a,c   Azad, Abul K ^a   Guirado, Evelyn ^a   Ni, Bin ^a   Gerberick, Abigail D ^a   He, Li Zhen ^b   Keler, Tibor ^b   Thomas, Lawrence J ^b   Lafuse, William P ^a   Schlesinger, Larry S ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Celldex Therapeutics Inc   (United Kingdom)

^c SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

C type lectin; human macrophage; lysosome; mannose receptor; Mycobacterium; phagosome; tuberculosis

Indexed keywords

CELL PROTEIN; FC RECEPTOR; FC RECEPTOR GAMMA CHAIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MANNOSE RECEPTOR; PAK PROTEIN; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN CDC42; PROTEIN TYROSINE PHOSPHATASE SHP 1; RAC PROTEIN; TYROSINE; UNCLASSIFIED DRUG; CDC42 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; GRB2 PROTEIN, HUMAN; LECTIN; MANNOSE BINDING LECTIN; P21 ACTIVATED KINASE; PROTEIN BINDING;

ARTICLE; BACTERIAL GROWTH; CELL FUSION; CELL MEMBRANE; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOPLASM; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; LYSOSOME; MACROPHAGE FUNCTION; MOLECULAR RECOGNITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TUBERCULOSIS; VESICLE TRAFFICKING; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; MACROPHAGE; MEMBRANE FUSION; METABOLISM; MICROBIOLOGY; PHOSPHORYLATION; PRIMARY CELL CULTURE; TRANSPORT VESICLE;

CDC42 GTP-BINDING PROTEIN; GENE EXPRESSION REGULATION; GRB2 ADAPTOR PROTEIN; HOST-PATHOGEN INTERACTIONS; HUMANS; LECTINS, C-TYPE; LYSOSOMES; MACROPHAGES; MANNOSE-BINDING LECTINS; MEMBRANE FUSION; MYCOBACTERIUM TUBERCULOSIS; P21-ACTIVATED KINASES; PHAGOCYTOSIS; PHAGOSOMES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RAC GTP-BINDING PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; SIGNAL TRANSDUCTION; TRANSPORT VESICLES; TYROSINE;

EID: 85030690262     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.09.034     Document Type: Article

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