Quercetin inhibits epithelial-mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial-mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells

OncoTargets and Therapy

Volumn 10, Issue , 2017, Pages 4719-4729

  Yu, Dinglai ^a   Ye, Tingting ^a   Xiang, Yukai ^a   Shi, Zhehao ^a   Zhang, Jie ^a   Lou, Bin ^a   Zhang, Fan ^a   Chen, Bicheng ^a,b   Zhou, Mengtao ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b Zhejiang Provincial Top Key Discipline in Surgery   (China)

Author keywords

EMT; MMPs; Pancreatic cancer; Quercetin; STAT3

Indexed keywords

INTERLEUKIN 6; MATRIX METALLOPROTEINASE; QUERCETIN; STAT3 PROTEIN;

ARTICLE; CELL INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; METASTASIS INHIBITION; MIGRATION INHIBITION; PANC-1 CELL LINE; PANCREAS CANCER; PATU 8988T CELL LINE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 85030215321     PISSN: None     EISSN: 11786930     Source Type: Journal    
DOI: 10.2147/OTT.S136840     Document Type: Article

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