A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Shan, Chao ^a   Muruato, Antonio E ^a   Jagger, Brett W ^b   Richner, Justin ^b   Nunes, Bruno T D ^a,c   Medeiros, Daniele B A ^a,c   Xie, Xuping ^a   Nunes, Jannyce G C ^a,c   Morabito, Kaitlyn M ^d   Kong, Wing Pui ^d   Pierson, Theodore C ^d   Barrett, Alan D ^a,e   Weaver, Scott C ^a,e   Rossi, Shannan L ^a,e   Vasconcelos, Pedro F C ^c,f   Graham, Barney S ^d   Diamond, Michael S ^b,c   Shi, Pei Yong ^a,e,f  

^a University of Texas Medical Branch School of Medicine   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTO EVANDRO CHAGAS   (Brazil)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^f UNIVERSIDADE DO ESTADO DO PARÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE; NEUTRALIZING ANTIBODY; VIRUS RNA; ZIKA VIRUS VACCINE; VIRUS VACCINE;

ABNORMALITY; DISEASE TRANSMISSION; EMBRYO; EMBRYONIC DEVELOPMENT; GENOME; IMMUNIZATION; INFECTIOUS DISEASE; MALE; NERVOUS SYSTEM DISORDER; PREGNANCY; PRIMATE; REPRODUCTIVE HEALTH; RODENT; SEXUALLY TRANSMITTED DISEASE; VACCINE; VIRUS; ZIKA VIRUS DISEASE;

3' UNTRANSLATED REGION; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYO; FEMALE; FETUS; FETUS TISSUE; FOCUS FORMING ASSAY; GENE DELETION; LIMIT OF DETECTION; MALE; MATERNAL BLOOD; MOUSE; NONHUMAN; OLIGOSPERMIA; ORCHITIS; PLACENTA TISSUE; PREGNANCY; RHESUS MONKEY; SINGLE DRUG DOSE; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS INJURY; VACCINATION; VACCINE IMMUNOGENICITY; VERTICAL TRANSMISSION; VIRUS GENOME; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSMISSION; ZIKA FEVER; ANIMAL; C57BL MOUSE; GENETICS; IMMUNOLOGY; PATHOLOGY; PRECLINICAL STUDY; PREVENTION AND CONTROL; TESTIS; TRANSMISSION; VIROLOGY; ZIKA VIRUS;

HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; MUS; PRIMATES; ZIKA VIRUS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; FEMALE; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MALE; MICE; MICE, INBRED C57BL; PREGNANCY; TESTIS; VACCINES, ATTENUATED; VIRAL VACCINES; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85029754852     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00737-8     Document Type: Article

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