Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016

Eurosurveillance

Volumn 21, Issue 32, 2016, Pages

  Nicastri, E ^a   Castilletti, Concetta ^a   Liuzzi, G ^a   Iannetta, M ^a   Capobianchi, M R ^a   Ippolito, G ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; VIRUS RNA;

ADULT; ANIMAL CELL; ANTIBODY TITER; ARTICLE; ASTHENIA; CASE REPORT; CYTOPATHOGENIC EFFECT; EMPORIATRICS; ERYTHEMA; FEVER; FOLLOW UP; HAITI; HUMAN; IMMUNOFLUORESCENCE TEST; ITALY; MALE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMEN ANALYSIS; VERO CELL LINE; VIRUS DETECTION; VIRUS NEUTRALIZATION; ZIKA FEVER; ZIKA VIRUS; BLOOD; GENETICS; ISOLATION AND PURIFICATION; RASH; SAFE SEX; SALIVA; SEXUALLY TRANSMITTED DISEASES, VIRAL; SPERM; SPOUSE; TIME FACTOR; TRAVEL; URINE; VIROLOGY; VIRUS SHEDDING; ZIKA VIRUS INFECTION;

ADULT; ASTHENIA; EXANTHEMA; FEVER; HAITI; HUMANS; ITALY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SAFE SEX; SALIVA; SEMEN; SEXUALLY TRANSMITTED DISEASES, VIRAL; SPOUSES; TIME FACTORS; TRAVEL; URINE; VIRUS SHEDDING; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85015352789     PISSN: 1025496X     EISSN: 15607917     Source Type: Journal    
DOI: 10.2807/1560-7917.ES.2016.21.32.30314     Document Type: Article

References (21)

1. Papa A, Perperidou P, Tzouli A, Castilletti C. West Nile virus--neutralizing antibodies in humans in Greece.Vector Borne Zoonotic Dis. 2010;10(7):655-8. Available from: DOI: 10.1089/ vbz.2010.0042 PMID: 20738157
2. Moureau G, Temmam S, Gonzalez JP, Charrel RN, Grard G, de Lamballerie X. A real-time RT-PCR method for the universal detection and identification of flaviviruses.Vector Borne Zoonotic Dis. 2007;7(4):467-77. Available from: DOI: 10.1089/ vbz.2007.0206 PMID: 18020965
3. Fréour T, Mirallié S, Hubert B, Splingart C, Barrière P, Maquart M, et al. Sexual transmission of Zika virus in an entirely asymptomatic couple returning from a Zika epidemic area, France, April 2016. Euro Surveill. 2016;21(23):30254. DOI: 10.2807/1560-7917.ES.2016.21.23.30254
4. World Health Organization (WHO). Prevention of sexual transmission of Zika virus. Interim guidance update. 7 June 2016. WHO/ZIKV/MOC/16.1 Rev.2. Geneva: WHO; 2016. Available from: http://apps.who.int/iris/bitstream/10665/204421/1/WHO_ZIKV_MOC_16.1_eng.pdf?ua=1
5. Foy BD, Kobylinski KC, Chilson Foy JL, Blitvich BJ, Travassos da Rosa A, Haddow AD, et al. Probable non-vector-borne transmission of Zika virus, Colorado, USA. Emerg Infect Dis. 2011;17(5):880-2. DOI: 10.3201/eid1705.101939
6. Frank C, Cadar D, Schlaphof A, Neddersen N, Günther S, Schmidt-Chanasit J, Tappe D. Sexual transmission of Zika virus in Germany, April 2016. Euro Surveill. 2016 9;21 (23):pii=30252. http://dx.doi.org/10.2807/1560-7917.ES.2016.21.23.30252
7. Turmel JM, Abgueguen P, Hubert B, Vandamme YM, Maquart M, Le Guillou-Guillemette H, Leparc-Goffart I. Late sexual transmission of Zika virus related to persistence in the semen. Lancet. 2016 18; 387:2501.
8. Bonaldo MC, Ribeiro IP, Lima NS, Dos Santos AAC, Menezes LSR, da Cruz SOD, et al. Isolation of Infective Zika Virus from Urine and Saliva of Patients in Brazil. PLoS Negl Trop Dis. 2016;10(6):e0004816. Available from: DOI: 10.1371/journal. pntd.0004816 PMID:27341420
9. Fourcade C, Mansuy JM, Dutertre M, Delpech M, Marchou B, Delobel P, et al. Viral load kinetics of Zika virus in plasma, urine and saliva in a couple returning from Martinique, French West Indies. J Clin Virol. 2016;82:1-4. DOI: 10.1016/j. jcv.2016.06.011
10. Perkasa A, Yudhaputri F, Haryanto S, Hayati RF, Ma’roef CN, Antonjaya U, et al. Isolation of Zika Virus from Febrile Patient, Indonesia. Emerg Infect Dis. 2016;22(5):924-5. DOI: 10.3201/ eid2205.151915
11. Mansuy JM, Dutertre M, Mengelle C, Fourcade C, Marchou B, Delobel P, et al. Zika virus: high infectious viral load in semen, a new sexually transmitted pathogen? Lancet Infect Dis. 2016;16(4):405. DOI: 10.1016/S1473-3099(16)00138-9
12. Atkinson B, Hearn P, Afrough B, Lumley S, Carter D, Aarons EJ, et al. Detection of Zika virus in semen. Emerg Infect Dis. 2016;22(5):940. DOI: 10.3201/eid2205.160107
13. Musso D, Roche C, Robin E, Nhan T, Teissier A, Cao-Lormeau VM. Potential sexual transmission of Zika virus. Emerg Infect Dis. 2015;21(2):359-61. Available from: DOI: 10.3201/ eid2102.141363 PMID: 25625872
14. Barzon L, Pacenti M, Berto A, Sinigaglia A, Franchin E, Lavezzo E, et al. Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016. Euro Surveill. 2016;21(10):30159. DOI: 10.2807/1560-7917. ES.2016.21.10.30159
15. Liuzzi G, Nicastri E, Puro V, Zumla A, Ippolito G. Zika virus in saliva-New challenges for prevention of human to human transmission. Eur J Intern Med. 2016 May 11. pii: S0953-6205(16)30091-7.
16. Mate SE, Kugelman JR, Nyenswah TG, Ladner JT, Wiley MR, Cordier-Lassalle T, et al. Molecular evidence of sexual transmission of Ebola virus. N Engl J Med. 2015;373(25):2448-54. DOI: 10.1056/NEJMoa1509773
17. Deen GF, Knust B, Broutet N, Sesay FR, Formenty P, Ross C, et al. Ebola RNA persistence in semen of Ebola virus disease survivors-preliminary report. N Engl J Med. 2015;14: Epub ahead of print. DOI: 10.1056/NEJMoa1511410
18. Huits RMHG, De Smet B, Ariën KK, Van Esbroeck M, de Jong BC, Bottieau E, et al. Kinetics of Zika virus persistence in semen. [Submitted]. Bull World Health Organ. E-pub. 6 Jul 2016. Posted to the Zika open site. http://dx.doi.org/10.2471/BLT.16.181370
19. European Centre for Disease Prevention and Control (ECDC). Rapid Risk Assessment. Zika virus disease epidemic: Sixth update, 20 May 2016. Stockholm: ECDC; 2016. Available from: http://ecdc.europa.eu/en/publications/Publications/zika%20virus%20rapid%20risk%20assessment%2010-05-2016.pdf
20. Duffy MR, Chen TH, Hancock WT, Powers AM, Kool JL, Lanciotti RS, et al. Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med. 2009;360(24):2536-43. DOI: 10.1056/NEJMoa0805715 PMID: 19516034
21. American Society for Reproductive Medicine (ASRM). Guidance for Providers Caring for Women and Men of Reproductive Age with Possible Zika Virus Exposure (Developed from CDC and FDA Published Guidance). Birmingham, AL: ASRM; 2016. Available from: https://www.asrm.org/uploadedFiles/ASRM_Content/News_and_Publications/News_and_Research/Press_Releases/2016-04/Zika%20Guidance%2004-06-16%20(2).pdf