The G-protein-coupled bile acid receptor Gpbar1 (TGR5) protects against renal inflammation and renal cancer cell proliferation and migration through antagonizing NF-κB and STAT3 signaling pathways

Oncotarget

Volumn 8, Issue 33, 2017, Pages 54378-54387

  Su, Jia ^a   Zhang, Qiqi ^a   Qi, Hui ^b   Wu, Linlin ^a   Li, Yuanqiang ^a   Yu, Donna ^d   Huang, Wendong ^d   Chen, Wei Dong ^b,c   Wang, Yan Dong ^a  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b HENAN UNIVERSITY   (China)

^c INNER MONGOLIA MEDICAL UNIVERSITY   (China)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Gpbar1; NF B; Renal inflammation; STAT3; TGR5

Indexed keywords

G PROTEIN COUPLED BILE ACID RECEPTOR GPBAR1; G PROTEIN COUPLED RECEPTOR; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STAT3 PROTEIN; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CANCER; LIMIT OF QUANTITATION; MOUSE; NEPHRITIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 85029046930     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.17533     Document Type: Article

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