-
2
-
-
79953301542
-
Do all roads lead to Rome? Routes to metastasis development
-
Sleeman JP, Nazarenko I and Thiele W: Do all roads lead to Rome? Routes to metastasis development. Int J Cancer 128: 2511-2526, 2011.
-
(2011)
Int J Cancer
, vol.128
, pp. 2511-2526
-
-
Sleeman, J.P.1
Nazarenko, I.2
Thiele, W.3
-
3
-
-
33746851956
-
Tumor metastasis: Mechanistic insights and clinical challenges
-
Steeg PS: Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 12: 895-904, 2006.
-
(2006)
Nat Med
, vol.12
, pp. 895-904
-
-
Steeg, P.S.1
-
4
-
-
84899078564
-
Epithelial-mesenchymal transition-A hallmark of breast cancer metastasis
-
Wang Y and Zhou BP: Epithelial-mesenchymal transition-A hallmark of breast cancer metastasis. Cancer Hallm 1: 38-49, 2013.
-
(2013)
Cancer Hallm
, vol.1
, pp. 38-49
-
-
Wang, Y.1
Zhou, B.P.2
-
5
-
-
0242456170
-
Axis of evil: Molecular mechanisms of cancer metastasis
-
Bogenrieder T and Herlyn M: Axis of evil: Molecular mechanisms of cancer metastasis. Oncogene 22: 6524-6536, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 6524-6536
-
-
Bogenrieder, T.1
Herlyn, M.2
-
6
-
-
79953689605
-
Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: Are they cousins or twins?
-
Kong D, Li Y, Wang Z and Sarkar FH: Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: Are they cousins or twins? Cancers (Basel) 3: 716-729, 2011.
-
(2011)
Cancers (Basel)
, vol.3
, pp. 716-729
-
-
Kong, D.1
Li, Y.2
Wang, Z.3
Sarkar, F.H.4
-
7
-
-
67650996280
-
Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
-
Acloque H, Adams MS, Fishwick K, Bronner-Fraser M and Nieto MA: Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119: 1438-1449, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
8
-
-
77954860342
-
Epithelialmesenchymal transition in cancer: Parallels between normal development and tumor progression
-
Micalizzi DS, Farabaugh SM and Ford HL: Epithelialmesenchymal transition in cancer: Parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia 15: 117-134, 2010.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 117-134
-
-
Micalizzi, D.S.1
Farabaugh, S.M.2
Ford, H.L.3
-
9
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K and Weinberg RA: Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9: 265-273, 2009.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
10
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
12
-
-
84902530878
-
The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer
-
Ginnebaugh KR, Ahmad A and Sarkar FH: The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer. Expert Opin Ther Targets 18: 731-745, 2014.
-
(2014)
Expert Opin Ther Targets
, vol.18
, pp. 731-745
-
-
Ginnebaugh, K.R.1
Ahmad, A.2
Sarkar, F.H.3
-
13
-
-
0029785873
-
Inhibition of chemiluminescence response of human mononuclear cells and suppression of mitogen-induced proliferation of spleen lymphocytes of mice by hispolon and hispidin
-
Ali NA, Lüdtke J, Pilgrim H and Lindequist U: Inhibition of chemiluminescence response of human mononuclear cells and suppression of mitogen-induced proliferation of spleen lymphocytes of mice by hispolon and hispidin. Pharmazie 51: 667-670, 1996.
-
(1996)
Pharmazie
, vol.51
, pp. 667-670
-
-
Ali, N.A.1
Lüdtke, J.2
Pilgrim, H.3
Lindequist, U.4
-
14
-
-
84855174914
-
Hispolon protects against acute liver damage in the rat by inhibiting lipid peroxidation, proinflammatory cytokine and oxidative stress and downregulating the expressions of iNOS, COX-2 and MMP-9
-
Huang GJ, Deng JS, Chiu CS, Liao JC, Hsieh WT, Sheu MJ and Wu CH: Hispolon protects against acute liver damage in the rat by inhibiting lipid peroxidation, proinflammatory cytokine and oxidative stress and downregulating the expressions of iNOS, COX-2 and MMP-9. Evid Based Complement Alternat Med 2012: 480714, 2012.
-
(2012)
Evid Based Complement Alternat Med 2012
-
-
Huang, G.J.1
Deng, J.S.2
Chiu, C.S.3
Liao, J.C.4
Hsieh, W.T.5
Sheu, M.J.6
Wu, C.H.7
-
15
-
-
84907188895
-
Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages
-
Yang LY, Shen SC, Cheng KT, Subbaraju GV, Chien CC and Chen YC: Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages. J Ethnopharmacol 156: 61-72, 2014.
-
(2014)
J Ethnopharmacol
, vol.156
, pp. 61-72
-
-
Yang, L.Y.1
Shen, S.C.2
Cheng, K.T.3
Subbaraju, G.V.4
Chien, C.C.5
Chen, Y.C.6
-
16
-
-
45049087026
-
Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway
-
Chen W, Zhao Z, Li L, Wu B, Chen SF, Zhou H, Wang Y and Li YQ: Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway. Free Radic Biol Med 45: 60-72, 2008.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 60-72
-
-
Chen, W.1
Zhao, Z.2
Li, L.3
Wu, B.4
Chen, S.F.5
Zhou, H.6
Wang, Y.7
Li, Y.Q.8
-
17
-
-
84887958084
-
Hispolon from Phellinuslinteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells
-
Chen YC, Chang HY, Deng JS, Chen JJ, Huang SS, Lin IH, Kuo WL, Chao W and Huang GJ: Hispolon from Phellinuslinteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells. Am J Chin Med 41: 1439-1457, 2013.
-
(2013)
Am J Chin Med
, vol.41
, pp. 1439-1457
-
-
Chen, Y.C.1
Chang, H.Y.2
Deng, J.S.3
Chen, J.J.4
Huang, S.S.5
Lin, I.H.6
Kuo, W.L.7
Chao, W.8
Huang, G.J.9
-
18
-
-
84892595350
-
Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3,-8 and-9
-
Chen YS, Lee SM, Lin CC and Liu CY: Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3,-8 and-9. Int J Mol Sci 15: 1201-1215, 2014.
-
(2014)
Int J Mol Sci
, vol.15
, pp. 1201-1215
-
-
Chen, Y.S.1
Lee, S.M.2
Lin, C.C.3
Liu, C.Y.4
-
19
-
-
79960034529
-
Hispolon induces apoptosis and cell cycle arrest of human hepatocellular carcinoma Hep3B cells by modulating ERK phosphorylation
-
Huang GJ, Deng JS, Huang SS and Hu ML: Hispolon induces apoptosis and cell cycle arrest of human hepatocellular carcinoma Hep3B cells by modulating ERK phosphorylation. J Agric Food Chem 59: 7104-7113, 2011.
-
(2011)
J Agric Food Chem
, vol.59
, pp. 7104-7113
-
-
Huang, G.J.1
Deng, J.S.2
Huang, S.S.3
Hu, M.L.4
-
20
-
-
68649089457
-
Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells
-
Lu TL, Huang GJ, Lu TJ, Wu JB, Wu CH, Yang TC, Iizuka A and Chen YF: Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells. Food Chem Toxicol 47: 2013-2021, 2009.
-
(2009)
Food Chem Toxicol
, vol.47
, pp. 2013-2021
-
-
Lu, T.L.1
Huang, G.J.2
Lu, T.J.3
Wu, J.B.4
Wu, C.H.5
Yang, T.C.6
Iizuka, A.7
Chen, Y.F.8
-
21
-
-
84907520196
-
Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transi-tion
-
Derynck R, Muthusamy BP and Saeteurn KY: Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transi-tion. Curr Opin Cell Biol 31: 56-66, 2014.
-
(2014)
Curr Opin Cell Biol
, vol.31
, pp. 56-66
-
-
Derynck, R.1
Muthusamy, B.P.2
Saeteurn, K.Y.3
-
22
-
-
84867992286
-
TGF-β signalling and its role in cancer progression and metastasis
-
Drabsch Y and ten Dijke P: TGF-β signalling and its role in cancer progression and metastasis. Cancer Metastasis Rev 31: 553-568, 2012.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 553-568
-
-
Drabsch, Y.1
Ten Dijke, P.2
-
24
-
-
24644487312
-
TGF-beta and epithelial-to-mesen-chymal transitions
-
Zavadil J and Böttinger EP: TGF-beta and epithelial-to-mesen-chymal transitions. Oncogene 24: 5764-5774, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Böttinger, E.P.2
-
25
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl P and Wolf K: Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer 3: 362-374, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
26
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene B and Berx G: Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13: 97-110, 2013.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
27
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R and Weinberg RA: The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
28
-
-
84859416889
-
Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells
-
Mulholland DJ, Kobayashi N, Ruscetti M, Zhi A, Tran LM, Huang J, Gleave M and Wu H: Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer research 72: 1878-1889, 2012.
-
(2012)
Cancer Research
, vol.72
, pp. 1878-1889
-
-
Mulholland, D.J.1
Kobayashi, N.2
Ruscetti, M.3
Zhi, A.4
Tran, L.M.5
Huang, J.6
Gleave, M.7
Wu, H.8
-
29
-
-
84893867951
-
TGF-β: Duality of function between tumor prevention and carcinogenesis
-
Principe DR, Doll JA, Bauer J, Jung B, Munshi HG, Bartholin L, Pasche B, Lee C and Grippo PJ: TGF-β: Duality of function between tumor prevention and carcinogenesis. J Natl Cancer Inst 106: djt369, 2014.
-
(2014)
J Natl Cancer Inst
, vol.106
-
-
Principe, D.R.1
Doll, J.A.2
Bauer, J.3
Jung, B.4
Munshi, H.G.5
Bartholin, L.6
Pasche, B.7
Lee, C.8
Grippo, P.J.9
-
30
-
-
84936890711
-
Hispolon inhibits the growth of estrogen receptor positive human breast cancer cells through modulation of estrogen receptor alpha
-
Jang EH, Jang SY, Cho IH, Hong D, Jung B, Park MJ and Kim JH: Hispolon inhibits the growth of estrogen receptor positive human breast cancer cells through modulation of estrogen receptor alpha. Biochem Biophys Res Commun 463: 917-922, 2015.
-
(2015)
Biochem Biophys Res Commun
, vol.463
, pp. 917-922
-
-
Jang, E.H.1
Jang, S.Y.2
Cho, I.H.3
Hong, D.4
Jung, B.5
Park, M.J.6
Kim, J.H.7
-
31
-
-
84954222932
-
Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors
-
Kim JH, Kim YC and Park B: Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors. Oncol Rep 35: 1020-1026, 2016.
-
(2016)
Oncol Rep
, vol.35
, pp. 1020-1026
-
-
Kim, J.H.1
Kim, Y.C.2
Park, B.3
-
32
-
-
84855999650
-
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma
-
Araki K, Shimura T, Suzuki H, Tsutsumi S, Wada W, Yajima T, Kobayahi T, Kubo N and Kuwano H: E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma. Br J Cancer 105: 1885-1893, 2011.
-
(2011)
Br J Cancer
, vol.105
, pp. 1885-1893
-
-
Araki, K.1
Shimura, T.2
Suzuki, H.3
Tsutsumi, S.4
Wada, W.5
Yajima, T.6
Kobayahi, T.7
Kubo, N.8
Kuwano, H.9
-
33
-
-
84894593599
-
Molecular mechanisms of epithelial-mesenchymal transition
-
Lamouille S, Xu J and Derynck R: Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15: 178-196, 2014.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 178-196
-
-
Lamouille, S.1
Xu, J.2
Derynck, R.3
-
34
-
-
84892390288
-
ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression
-
Li Z, Zhang L, Ma Z, Yang M, Tang J, Fu Y, Mao Y, Hong X and Zhang Y: ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression. Oncol Rep 30: 2859-2863, 2013.
-
(2013)
Oncol Rep
, vol.30
, pp. 2859-2863
-
-
Li, Z.1
Zhang, L.2
Ma, Z.3
Yang, M.4
Tang, J.5
Fu, Y.6
Mao, Y.7
Hong, X.8
Zhang, Y.9
-
35
-
-
84896721016
-
Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells
-
Masui T, Ota I, Yook JI, Mikami S, Yane K, Yamanaka T and Hosoi H: Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells. Int J Oncol 44: 693-699, 2014.
-
(2014)
Int J Oncol
, vol.44
, pp. 693-699
-
-
Masui, T.1
Ota, I.2
Yook, J.I.3
Mikami, S.4
Yane, K.5
Yamanaka, T.6
Hosoi, H.7
-
36
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S and Derynck R: TGF-beta-induced epithelial to mesenchymal transition. Cell Res 19: 156-172, 2009.
-
(2009)
Cell Res
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
37
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Francí C, Domínguez D, Monfar M, Baulida J and García De Herreros A: The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2: 84-89, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Francí, C.3
Domínguez, D.4
Monfar, M.5
Baulida, J.6
García De Herreros, A.7
-
38
-
-
40249113328
-
Direct regulation of TWIST by HIF-1alpha promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ, Teng SC and Wu KJ: Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol 10: 295-305, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Liu, C.J.6
Teng, S.C.7
Wu, K.J.8
-
39
-
-
0028933142
-
Twist is required in head mesenchyme for cranial neural tube morphogenesis
-
Chen ZF and Behringer RR: Twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev 9: 686-699, 1995.
-
(1995)
Genes Dev
, vol.9
, pp. 686-699
-
-
Chen, Z.F.1
Behringer, R.R.2
-
40
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A and Weinberg RA: Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117: 927-939, 2004.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
|