메뉴 건너뛰기




Volumn 14, Issue 4, 2017, Pages 4866-4872

Hispolon as an inhibitor of TGF-β-induced epithelial-mesenchymal transition in human epithelial cancer cells by co-regulation of TGF-β-Snail/Twist axis

Author keywords

Epithelial mesenchymal transition; Hispolon; Invasion; Migration; Transforming growth factor

Indexed keywords

HISPOLON; PHENOL DERIVATIVE; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 85028914675     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2017.6789     Document Type: Article
Times cited : (15)

References (40)
  • 2
    • 79953301542 scopus 로고    scopus 로고
    • Do all roads lead to Rome? Routes to metastasis development
    • Sleeman JP, Nazarenko I and Thiele W: Do all roads lead to Rome? Routes to metastasis development. Int J Cancer 128: 2511-2526, 2011.
    • (2011) Int J Cancer , vol.128 , pp. 2511-2526
    • Sleeman, J.P.1    Nazarenko, I.2    Thiele, W.3
  • 3
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • Steeg PS: Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 12: 895-904, 2006.
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 4
    • 84899078564 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition-A hallmark of breast cancer metastasis
    • Wang Y and Zhou BP: Epithelial-mesenchymal transition-A hallmark of breast cancer metastasis. Cancer Hallm 1: 38-49, 2013.
    • (2013) Cancer Hallm , vol.1 , pp. 38-49
    • Wang, Y.1    Zhou, B.P.2
  • 5
    • 0242456170 scopus 로고    scopus 로고
    • Axis of evil: Molecular mechanisms of cancer metastasis
    • Bogenrieder T and Herlyn M: Axis of evil: Molecular mechanisms of cancer metastasis. Oncogene 22: 6524-6536, 2003.
    • (2003) Oncogene , vol.22 , pp. 6524-6536
    • Bogenrieder, T.1    Herlyn, M.2
  • 6
    • 79953689605 scopus 로고    scopus 로고
    • Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: Are they cousins or twins?
    • Kong D, Li Y, Wang Z and Sarkar FH: Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: Are they cousins or twins? Cancers (Basel) 3: 716-729, 2011.
    • (2011) Cancers (Basel) , vol.3 , pp. 716-729
    • Kong, D.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 7
    • 67650996280 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
    • Acloque H, Adams MS, Fishwick K, Bronner-Fraser M and Nieto MA: Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119: 1438-1449, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1438-1449
    • Acloque, H.1    Adams, M.S.2    Fishwick, K.3    Bronner-Fraser, M.4    Nieto, M.A.5
  • 8
    • 77954860342 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition in cancer: Parallels between normal development and tumor progression
    • Micalizzi DS, Farabaugh SM and Ford HL: Epithelialmesenchymal transition in cancer: Parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia 15: 117-134, 2010.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 9
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K and Weinberg RA: Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9: 265-273, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 10
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 12
    • 84902530878 scopus 로고    scopus 로고
    • The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer
    • Ginnebaugh KR, Ahmad A and Sarkar FH: The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer. Expert Opin Ther Targets 18: 731-745, 2014.
    • (2014) Expert Opin Ther Targets , vol.18 , pp. 731-745
    • Ginnebaugh, K.R.1    Ahmad, A.2    Sarkar, F.H.3
  • 13
    • 0029785873 scopus 로고    scopus 로고
    • Inhibition of chemiluminescence response of human mononuclear cells and suppression of mitogen-induced proliferation of spleen lymphocytes of mice by hispolon and hispidin
    • Ali NA, Lüdtke J, Pilgrim H and Lindequist U: Inhibition of chemiluminescence response of human mononuclear cells and suppression of mitogen-induced proliferation of spleen lymphocytes of mice by hispolon and hispidin. Pharmazie 51: 667-670, 1996.
    • (1996) Pharmazie , vol.51 , pp. 667-670
    • Ali, N.A.1    Lüdtke, J.2    Pilgrim, H.3    Lindequist, U.4
  • 14
    • 84855174914 scopus 로고    scopus 로고
    • Hispolon protects against acute liver damage in the rat by inhibiting lipid peroxidation, proinflammatory cytokine and oxidative stress and downregulating the expressions of iNOS, COX-2 and MMP-9
    • Huang GJ, Deng JS, Chiu CS, Liao JC, Hsieh WT, Sheu MJ and Wu CH: Hispolon protects against acute liver damage in the rat by inhibiting lipid peroxidation, proinflammatory cytokine and oxidative stress and downregulating the expressions of iNOS, COX-2 and MMP-9. Evid Based Complement Alternat Med 2012: 480714, 2012.
    • (2012) Evid Based Complement Alternat Med 2012
    • Huang, G.J.1    Deng, J.S.2    Chiu, C.S.3    Liao, J.C.4    Hsieh, W.T.5    Sheu, M.J.6    Wu, C.H.7
  • 15
    • 84907188895 scopus 로고    scopus 로고
    • Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages
    • Yang LY, Shen SC, Cheng KT, Subbaraju GV, Chien CC and Chen YC: Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages. J Ethnopharmacol 156: 61-72, 2014.
    • (2014) J Ethnopharmacol , vol.156 , pp. 61-72
    • Yang, L.Y.1    Shen, S.C.2    Cheng, K.T.3    Subbaraju, G.V.4    Chien, C.C.5    Chen, Y.C.6
  • 16
    • 45049087026 scopus 로고    scopus 로고
    • Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway
    • Chen W, Zhao Z, Li L, Wu B, Chen SF, Zhou H, Wang Y and Li YQ: Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway. Free Radic Biol Med 45: 60-72, 2008.
    • (2008) Free Radic Biol Med , vol.45 , pp. 60-72
    • Chen, W.1    Zhao, Z.2    Li, L.3    Wu, B.4    Chen, S.F.5    Zhou, H.6    Wang, Y.7    Li, Y.Q.8
  • 18
    • 84892595350 scopus 로고    scopus 로고
    • Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3,-8 and-9
    • Chen YS, Lee SM, Lin CC and Liu CY: Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3,-8 and-9. Int J Mol Sci 15: 1201-1215, 2014.
    • (2014) Int J Mol Sci , vol.15 , pp. 1201-1215
    • Chen, Y.S.1    Lee, S.M.2    Lin, C.C.3    Liu, C.Y.4
  • 19
    • 79960034529 scopus 로고    scopus 로고
    • Hispolon induces apoptosis and cell cycle arrest of human hepatocellular carcinoma Hep3B cells by modulating ERK phosphorylation
    • Huang GJ, Deng JS, Huang SS and Hu ML: Hispolon induces apoptosis and cell cycle arrest of human hepatocellular carcinoma Hep3B cells by modulating ERK phosphorylation. J Agric Food Chem 59: 7104-7113, 2011.
    • (2011) J Agric Food Chem , vol.59 , pp. 7104-7113
    • Huang, G.J.1    Deng, J.S.2    Huang, S.S.3    Hu, M.L.4
  • 20
    • 68649089457 scopus 로고    scopus 로고
    • Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells
    • Lu TL, Huang GJ, Lu TJ, Wu JB, Wu CH, Yang TC, Iizuka A and Chen YF: Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells. Food Chem Toxicol 47: 2013-2021, 2009.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2013-2021
    • Lu, T.L.1    Huang, G.J.2    Lu, T.J.3    Wu, J.B.4    Wu, C.H.5    Yang, T.C.6    Iizuka, A.7    Chen, Y.F.8
  • 21
    • 84907520196 scopus 로고    scopus 로고
    • Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transi-tion
    • Derynck R, Muthusamy BP and Saeteurn KY: Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transi-tion. Curr Opin Cell Biol 31: 56-66, 2014.
    • (2014) Curr Opin Cell Biol , vol.31 , pp. 56-66
    • Derynck, R.1    Muthusamy, B.P.2    Saeteurn, K.Y.3
  • 22
    • 84867992286 scopus 로고    scopus 로고
    • TGF-β signalling and its role in cancer progression and metastasis
    • Drabsch Y and ten Dijke P: TGF-β signalling and its role in cancer progression and metastasis. Cancer Metastasis Rev 31: 553-568, 2012.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 553-568
    • Drabsch, Y.1    Ten Dijke, P.2
  • 24
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesen-chymal transitions
    • Zavadil J and Böttinger EP: TGF-beta and epithelial-to-mesen-chymal transitions. Oncogene 24: 5764-5774, 2005.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Böttinger, E.P.2
  • 25
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • Friedl P and Wolf K: Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer 3: 362-374, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 26
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • De Craene B and Berx G: Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13: 97-110, 2013.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 27
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R and Weinberg RA: The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 28
    • 84859416889 scopus 로고    scopus 로고
    • Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells
    • Mulholland DJ, Kobayashi N, Ruscetti M, Zhi A, Tran LM, Huang J, Gleave M and Wu H: Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer research 72: 1878-1889, 2012.
    • (2012) Cancer Research , vol.72 , pp. 1878-1889
    • Mulholland, D.J.1    Kobayashi, N.2    Ruscetti, M.3    Zhi, A.4    Tran, L.M.5    Huang, J.6    Gleave, M.7    Wu, H.8
  • 30
    • 84936890711 scopus 로고    scopus 로고
    • Hispolon inhibits the growth of estrogen receptor positive human breast cancer cells through modulation of estrogen receptor alpha
    • Jang EH, Jang SY, Cho IH, Hong D, Jung B, Park MJ and Kim JH: Hispolon inhibits the growth of estrogen receptor positive human breast cancer cells through modulation of estrogen receptor alpha. Biochem Biophys Res Commun 463: 917-922, 2015.
    • (2015) Biochem Biophys Res Commun , vol.463 , pp. 917-922
    • Jang, E.H.1    Jang, S.Y.2    Cho, I.H.3    Hong, D.4    Jung, B.5    Park, M.J.6    Kim, J.H.7
  • 31
    • 84954222932 scopus 로고    scopus 로고
    • Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors
    • Kim JH, Kim YC and Park B: Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors. Oncol Rep 35: 1020-1026, 2016.
    • (2016) Oncol Rep , vol.35 , pp. 1020-1026
    • Kim, J.H.1    Kim, Y.C.2    Park, B.3
  • 32
    • 84855999650 scopus 로고    scopus 로고
    • E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma
    • Araki K, Shimura T, Suzuki H, Tsutsumi S, Wada W, Yajima T, Kobayahi T, Kubo N and Kuwano H: E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma. Br J Cancer 105: 1885-1893, 2011.
    • (2011) Br J Cancer , vol.105 , pp. 1885-1893
    • Araki, K.1    Shimura, T.2    Suzuki, H.3    Tsutsumi, S.4    Wada, W.5    Yajima, T.6    Kobayahi, T.7    Kubo, N.8    Kuwano, H.9
  • 33
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J and Derynck R: Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15: 178-196, 2014.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 34
    • 84892390288 scopus 로고    scopus 로고
    • ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression
    • Li Z, Zhang L, Ma Z, Yang M, Tang J, Fu Y, Mao Y, Hong X and Zhang Y: ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression. Oncol Rep 30: 2859-2863, 2013.
    • (2013) Oncol Rep , vol.30 , pp. 2859-2863
    • Li, Z.1    Zhang, L.2    Ma, Z.3    Yang, M.4    Tang, J.5    Fu, Y.6    Mao, Y.7    Hong, X.8    Zhang, Y.9
  • 35
    • 84896721016 scopus 로고    scopus 로고
    • Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells
    • Masui T, Ota I, Yook JI, Mikami S, Yane K, Yamanaka T and Hosoi H: Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells. Int J Oncol 44: 693-699, 2014.
    • (2014) Int J Oncol , vol.44 , pp. 693-699
    • Masui, T.1    Ota, I.2    Yook, J.I.3    Mikami, S.4    Yane, K.5    Yamanaka, T.6    Hosoi, H.7
  • 36
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • Xu J, Lamouille S and Derynck R: TGF-beta-induced epithelial to mesenchymal transition. Cell Res 19: 156-172, 2009.
    • (2009) Cell Res , vol.19 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 39
    • 0028933142 scopus 로고
    • Twist is required in head mesenchyme for cranial neural tube morphogenesis
    • Chen ZF and Behringer RR: Twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev 9: 686-699, 1995.
    • (1995) Genes Dev , vol.9 , pp. 686-699
    • Chen, Z.F.1    Behringer, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.