Analyses of extracellular protein production in Bacillus subtilis – I: Genome-scale metabolic model reconstruction based on updated gene-enzyme-reaction data

Biochemical Engineering Journal

Volumn 127, Issue , 2017, Pages 229-241

  Kocabaş, Pınar ^a   Çalık, Pınar ^b   Çalık, Güzide ^a   Özdamar, Tunçer H ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Bacillus subtilis; Flux balance analysis; Gene enzyme reaction data; Genome scale model; Metabolic engineering sites; Serine alkaline protease

Indexed keywords

AMINO ACIDS; BACTERIOLOGY; ENZYME ACTIVITY; ENZYMES; METABOLIC ENGINEERING; METABOLISM; THERMOANALYSIS;

ALKALINE PROTEASE; BACILLUS SUBTILIS; ENZYME REACTION; FLUX BALANCE ANALYSIS; GENOME-SCALE MODEL;

GENES;

ALKALINE PROTEINASE; ASPARAGINE; ASPARTIC ACID; CELL PROTEIN; GLUTAMIC ACID; ISOLEUCINE; OXYGEN; THREONINE;

ACCURACY; AMINO ACID SYNTHESIS; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GENOME; BATCH FERMENTATION; BIOPROCESS; CARBON METABOLISM; CARBON SOURCE; CELL GROWTH; CHEMICAL STRUCTURE; COMPARATIVE STUDY; COMPUTER MODEL; CONCENTRATION RATIO; ELECTRON TRANSPORT; ENZYME MECHANISM; EQUILIBRIUM CONSTANT; GENE DELETION; GLUCONEOGENESIS; GLUCOSE TRANSPORT; HOST CELL; INTRACELLULAR SPACE; KINETIC PARAMETERS; MAXIMUM FLUX; METABOLIC ENGINEERING; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REACTOR OPERATION; STOICHIOMETRY; THERMODYNAMICS; VALIDATION PROCESS;

EID: 85028613164     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2017.07.005     Document Type: Article

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