Combined effect of improved cell yield and increased specific productivity enhances recombinant enzyme production in genome-reduced Bacillus subtilis strain MGB874

Applied and Environmental Microbiology

Volumn 77, Issue 23, 2011, Pages 8370-8381

  Manabe, Kenji ^a,b   Kageyama, Yasushi ^a   Morimoto, Takuya ^a   Ozawa, Tadahiro ^a   Sawada, Kazuhisa ^a   Endo, Keiji ^a   Tohata, Masatoshi ^a   Ara, Katsutoshi ^a   Ozaki, Katsuya ^a   Ogasawara, Naotake ^b  

^a KAO CORPORATION   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS SUBTILIS STRAINS; CELL YIELDS; COMBINED EFFECT; COPY NUMBER; ENZYME PRODUCTION; ENZYME PRODUCTIVITY; EXPRESSION LEVELS; GENOMIC DELETIONS; PROMOTER ACTIVITIES; RECOMBINANT ENZYMES; REDUCTION STRATEGY; SPECIFIC PRODUCTIVITY; SUBTILIS; TARGET GENES; WILD-TYPE STRAIN;

AMINO ACIDS; BACILLI; BACTERIOLOGY; BIOCHEMISTRY; CELLS; GENE EXPRESSION; MACHINERY; PRODUCTIVITY;

ENZYMES;

ENZYME; GLUTAMIC ACID; RECOMBINANT PROTEIN;

BACTERIUM; ENZYME ACTIVITY; GENOMICS; METABOLISM; PLASMID; PROTEIN; RECOMBINATION;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GENOME; BIOSYNTHESIS; GENE DELETION; GENE DOSAGE; GENETICS; METABOLISM; PLASMID; PROMOTER REGION;

BACILLUS SUBTILIS; ENZYMES; GENE DOSAGE; GENOME, BACTERIAL; GLUTAMIC ACID; PLASMIDS; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; SEQUENCE DELETION;

EID: 83255186862     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.06136-11     Document Type: Article

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