Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice

Journal of Steroid Biochemistry and Molecular Biology

Volumn 174, Issue , 2017, Pages 96-113

  Zhao, Yangang ^a   He, Li ^a   Zhang, Yuanyuan ^a   Zhao, Jikai ^a   Liu, Zhi ^a   Xing, Fangzhou ^b   Liu, Mengying ^a   Feng, Ziqi ^a   Li, Wei ^a   Zhang, Jiqiang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b SOUTHWEST UNIVERSITY   (China)

Author keywords

Actin polymerization; Estrogen receptor; Estrogens; mTORC2; Rictor; Spatial learning; Steroid receptor coactivator 1

Indexed keywords

ACTIN; AROMATASE; BETA ACTIN; COFILIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; F ACTIN; G ACTIN; LENTIVIRUS VECTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROFILIN; PROFILIN 1; PROTEIN KINASE B; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG; ACTIN DEPOLYMERIZING FACTOR; CARRIER PROTEIN; ESTROGEN; MULTIPROTEIN COMPLEX; NCOA1 PROTEIN, MOUSE; RICTOR PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ACTIN POLYMERIZATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC SPINE; EMBRYO; ENZYME PHOSPHORYLATION; FEMALE; GENE SILENCING; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IN VITRO STUDY; LEARNING DISORDER; LENTIVIRINAE; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; MTOR SIGNALING; NONHUMAN; OVARIECTOMY; PROTEIN PHOSPHORYLATION; SPATIAL LEARNING; SPATIAL MEMORY; UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; METABOLISM; PHYSIOLOGY; POLYMERIZATION;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; AROMATASE; CARRIER PROTEINS; CELL LINE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; FEMALE; HIPPOCAMPUS; MICE, INBRED C57BL; MULTIPROTEIN COMPLEXES; NUCLEAR RECEPTOR COACTIVATOR 1; OVARIECTOMY; POLYMERIZATION; PROTO-ONCOGENE PROTEINS C-AKT; SPATIAL MEMORY; TOR SERINE-THREONINE KINASES;

EID: 85028510338     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2017.08.003     Document Type: Article

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