The radical-SAM enzyme Viperin catalyzes reductive addition of a 5′-deoxyadenosyl radical to UDP-glucose in vitro

FEBS Letters

Volumn 591, Issue 16, 2017, Pages 2394-2405

  Honarmand Ebrahimi, Kourosh ^a   Carr, Stephen B ^b,c   McCullagh, James ^a   Wickens, James ^a   Rees, Nicholas H ^a   Cantley, James ^a   Armstrong, Fraser A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

immune system; radical SAM; Viperin

Indexed keywords

5' DEOXYADENOSYL RADICAL; ENZYME; HYDROGEN; RADICAL; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE; VIPERIN; DEOXYADENOSINE DERIVATIVE; FREE RADICAL; FUNGAL PROTEIN;

ADDITION REACTION; BIOCHEMICAL ANALYSIS; BIOPHYSICS; CATALYSIS; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HUMAN; IN VITRO STUDY; LETTER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR DOCKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION; THERMOSTABILITY; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMISTRY; CONSERVED SEQUENCE; ENZYMOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; SORDARIALES;

AMINO ACID SEQUENCE; BIOCATALYSIS; CONSERVED SEQUENCE; DEOXYADENOSINES; FREE RADICALS; FUNGAL PROTEINS; HYDROGEN; MOLECULAR DOCKING SIMULATION; OXIDATION-REDUCTION; PROTEIN CONFORMATION; S-ADENOSYLMETHIONINE; SORDARIALES; URIDINE DIPHOSPHATE GLUCOSE;

EID: 85028395690     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1002/1873-3468.12769     Document Type: Article

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