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Volumn 129, Issue 13, 2017, Pages 1779-1790

Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; FLT3 LIGAND; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CEBPA; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; DNA BINDING PROTEIN; ONCOPROTEIN; TET2 PROTEIN, HUMAN; TET2 PROTEIN, MOUSE;

EID: 85028337206     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-06-721977     Document Type: Article
Times cited : (20)

References (30)
  • 1
    • 70350464349 scopus 로고    scopus 로고
    • A coming-of-age story: Activation-induced cytidine deaminase turns 10
    • Delker RK, Fugmann SD, Papavasiliou FN. A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat Immunol. 2009;10(11):1147-1153.
    • (2009) Nat Immunol , vol.10 , Issue.11 , pp. 1147-1153
    • Delker, R.K.1    Fugmann, S.D.2    Papavasiliou, F.N.3
  • 2
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 2000; 102(5):553-563.
    • (2000) Cell , vol.102 , Issue.5 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 3
    • 84862865669 scopus 로고    scopus 로고
    • Immunoglobulin class-switch DNA recombination: Induction, targeting and beyond
    • Xu Z, Zan H, Pone EJ, Mai T, Casali P. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nat Rev Immunol. 2012;12(7): 517-531.
    • (2012) Nat Rev Immunol , vol.12 , Issue.7 , pp. 517-531
    • Xu, Z.1    Zan, H.2    Pone, E.J.3    Mai, T.4    Casali, P.5
  • 4
    • 57649196594 scopus 로고    scopus 로고
    • DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
    • Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell. 2008;135(7): 1201-1212.
    • (2008) Cell , vol.135 , Issue.7 , pp. 1201-1212
    • Rai, K.1    Huggins, I.J.2    James, S.R.3    Karpf, A.R.4    Jones, D.A.5    Cairns, B.R.6
  • 5
    • 77249148019 scopus 로고    scopus 로고
    • Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
    • Popp C, Dean W, Feng S, et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature. 2010;463(7284):1101-1105.
    • (2010) Nature , vol.463 , Issue.7284 , pp. 1101-1105
    • Popp, C.1    Dean, W.2    Feng, S.3
  • 6
    • 77649104794 scopus 로고    scopus 로고
    • Reprogramming towards pluripotency requires AID-dependent DNA demethylation
    • Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature. 2010;463(7284): 1042-1047.
    • (2010) Nature , vol.463 , Issue.7284 , pp. 1042-1047
    • Bhutani, N.1    Brady, J.J.2    Damian, M.3    Sacco, A.4    Corbel, S.Y.5    Blau, H.M.6
  • 7
    • 79959937861 scopus 로고    scopus 로고
    • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
    • Cortellino S, Xu J, Sannai M, et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell. 2011;146(1):67-79.
    • (2011) Cell , vol.146 , Issue.1 , pp. 67-79
    • Cortellino, S.1    Xu, J.2    Sannai, M.3
  • 8
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell. 2011;145(3):423-434.
    • (2011) Cell , vol.145 , Issue.3 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 9
    • 80052933429 scopus 로고    scopus 로고
    • DNA demethylation dynamics
    • Bhutani N, Burns DM, Blau HM. DNA demethylation dynamics. Cell. 2011;146(6): 866-872.
    • (2011) Cell , vol.146 , Issue.6 , pp. 866-872
    • Bhutani, N.1    Burns, D.M.2    Blau, H.M.3
  • 10
    • 66249137734 scopus 로고    scopus 로고
    • Mutation in TET2 in myeloid cancers
    • Delhommeau F, Dupont S, Della Valle V, et al. Mutation in TET2 in myeloid cancers. N Engl J Med. 2009;360(22):2289-2301.
    • (2009) N Engl J Med , vol.360 , Issue.22 , pp. 2289-2301
    • Delhommeau, F.1    Dupont, S.2    Della Valle, V.3
  • 11
    • 67649876132 scopus 로고    scopus 로고
    • Acquired mutations in TET2 are common in myelodysplastic syndromes
    • Langemeijer SM, Kuiper RP, Berends M, et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet. 2009; 41(7):838-842.
    • (2009) Nat Genet , vol.41 , Issue.7 , pp. 838-842
    • Langemeijer, S.M.1    Kuiper, R.P.2    Berends, M.3
  • 12
    • 67651065502 scopus 로고    scopus 로고
    • Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
    • Abdel-Wahab O, Mullally A, Hedvat C, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 2009;114(1):144-147.
    • (2009) Blood , vol.114 , Issue.1 , pp. 144-147
    • Abdel-Wahab, O.1    Mullally, A.2    Hedvat, C.3
  • 13
    • 67650588639 scopus 로고    scopus 로고
    • Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/ myeloproliferative neoplasms
    • Jankowska AM, Szpurka H, Tiu RV, et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/ myeloproliferative neoplasms. Blood. 2009; 113(25):6403-6410.
    • (2009) Blood , vol.113 , Issue.25 , pp. 6403-6410
    • Jankowska, A.M.1    Szpurka, H.2    Tiu, R.V.3
  • 14
    • 79960064353 scopus 로고    scopus 로고
    • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    • Moran-Crusio K, Reavie L, Shih A, et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell. 2011;20(1):11-24.
    • (2011) Cancer Cell , vol.20 , Issue.1 , pp. 11-24
    • Moran-Crusio, K.1    Reavie, L.2    Shih, A.3
  • 15
    • 79960062301 scopus 로고    scopus 로고
    • TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron C, Couronné L, Della Valle V, et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell. 2011;20(1):25-38.
    • (2011) Cancer Cell , vol.20 , Issue.1 , pp. 25-38
    • Quivoron, C.1    Couronné, L.2    Della Valle, V.3
  • 16
    • 80052285127 scopus 로고    scopus 로고
    • Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
    • Li Z, Cai X, Cai CL, et al. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood. 2011;118(17):4509-4518.
    • (2011) Blood , vol.118 , Issue.17 , pp. 4509-4518
    • Li, Z.1    Cai, X.2    Cai, C.L.3
  • 17
    • 57149146036 scopus 로고    scopus 로고
    • AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
    • Robbiani DF, Bothmer A, Callen E, et al. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell. 2008; 135(6):1028-1038.
    • (2008) Cell , vol.135 , Issue.6 , pp. 1028-1038
    • Robbiani, D.F.1    Bothmer, A.2    Callen, E.3
  • 18
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Australian Pancreatic Cancer Genome Initiative; ICGC PedBrain. [published correction appears in Nature. 2013;502(7470): 258]
    • Alexandrov LB, Nik-Zainal S, Wedge DC, et al; Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain. Signatures of mutational processes in human cancer [published correction appears in Nature. 2013;502(7470): 258]. Nature. 2013;500(7463):415-421.
    • (2013) Nature , vol.500 , Issue.7463 , pp. 415-421
    • Alexandrov, L.B.1    Nik-Zainal, S.2    Wedge, D.C.3
  • 19
    • 84881476513 scopus 로고    scopus 로고
    • AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes
    • Kumar R, DiMenna L, Schrode N, et al. AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature. 2013;500(7460):89-92.
    • (2013) Nature , vol.500 , Issue.7460 , pp. 89-92
    • Kumar, R.1    DiMenna, L.2    Schrode, N.3
  • 20
    • 84928011690 scopus 로고    scopus 로고
    • Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia
    • Shih AH, Jiang Y, Meydan C, et al. Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Cancer Cell. 2015;27(4):502-515.
    • (2015) Cancer Cell , vol.27 , Issue.4 , pp. 502-515
    • Shih, A.H.1    Jiang, Y.2    Meydan, C.3
  • 21
    • 57249084011 scopus 로고    scopus 로고
    • Visualizing high-dimensional data using t-SNE
    • van der Maaten L, Hinton GE. Visualizing high-dimensional data using t-SNE. J Mach Learn Res. 2008;9(11):2579-2605.
    • (2008) J Mach Learn Res , vol.9 , Issue.11 , pp. 2579-2605
    • Van Der Maaten, L.1    Hinton, G.E.2
  • 22
    • 84866860221 scopus 로고    scopus 로고
    • MethylKit: A comprehensive R package for the analysis of genome-wide DNA methylation profiles
    • Akalin A, Kormaksson M, Li S, et al. methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Genome Biol. 2012;13(10):R87.
    • (2012) Genome Biol , vol.13 , Issue.10 , pp. R87
    • Akalin, A.1    Kormaksson, M.2    Li, S.3
  • 23
    • 84872119981 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-6 and cancer
    • Bach LA, Fu P, Yang Z. Insulin-like growth factor-binding protein-6 and cancer. Clin Sci (Lond). 2013;124(4):215-229.
    • (2013) Clin Sci (lond) , vol.124 , Issue.4 , pp. 215-229
    • Bach, L.A.1    Fu, P.2    Yang, Z.3
  • 24
    • 33645869265 scopus 로고    scopus 로고
    • Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases
    • Honma M, Higuchi O, Shirakata M, et al. Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases. Genes Cells. 2006;11(2):143-151.
    • (2006) Genes Cells , vol.11 , Issue.2 , pp. 143-151
    • Honma, M.1    Higuchi, O.2    Shirakata, M.3
  • 25
    • 77649191497 scopus 로고    scopus 로고
    • Identification of DOK genes as lung tumor suppressors
    • Berger AH, Niki M, Morotti A, et al. Identification of DOK genes as lung tumor suppressors. Nat Genet. 2010;42(3):216-223.
    • (2010) Nat Genet , vol.42 , Issue.3 , pp. 216-223
    • Berger, A.H.1    Niki, M.2    Morotti, A.3
  • 26
    • 79960768558 scopus 로고    scopus 로고
    • Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors
    • Pronier E, Almire C, Mokrani H, et al. Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors. Blood. 2011;118(9): 2551-2555.
    • (2011) Blood , vol.118 , Issue.9 , pp. 2551-2555
    • Pronier, E.1    Almire, C.2    Mokrani, H.3
  • 27
    • 50349093233 scopus 로고    scopus 로고
    • The AID/APOBEC family of nucleic acid mutators
    • Conticello SG. The AID/APOBEC family of nucleic acid mutators. Genome Biol. 2008;9(6):229.
    • (2008) Genome Biol , vol.9 , Issue.6 , pp. 229
    • Conticello, S.G.1
  • 28
    • 84908679499 scopus 로고    scopus 로고
    • Hydroxymethylation of DNA influences nucleosomal conformation and stability in vitro
    • Mendonca A, Chang EH, Liu W, Yuan C. Hydroxymethylation of DNA influences nucleosomal conformation and stability in vitro. Biochim Biophys Acta. 2014;1839(11):1323-1329.
    • (2014) Biochim Biophys Acta , vol.1839 , Issue.11 , pp. 1323-1329
    • Mendonca, A.1    Chang, E.H.2    Liu, W.3    Yuan, C.4
  • 29
    • 84958103136 scopus 로고    scopus 로고
    • 5-hydroxymethylcytosine marks sites of DNA damage and promotes genome stability
    • Kafer GR, Li X, Horii T, et al. 5-hydroxymethylcytosine marks sites of DNA damage and promotes genome stability. Cell Reports. 2016;14(6):1283-1292.
    • (2016) Cell Reports , vol.14 , Issue.6 , pp. 1283-1292
    • Kafer, G.R.1    Li, X.2    Horii, T.3
  • 30
    • 77956902023 scopus 로고    scopus 로고
    • Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    • Ji H, Ehrlich LI, Seita J, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010; 467(7313):338-342.
    • (2010) Nature , vol.467 , Issue.7313 , pp. 338-342
    • Ji, H.1    Ehrlich, L.I.2    Seita, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.