In vivo vascularization of cell sheets provided better long-term tissue survival than injection of cell suspension

Journal of Tissue Engineering and Regenerative Medicine

Volumn 10, Issue 8, 2016, Pages 700-710

  Takeuchi, Ryohei ^a,b,c   Kuruma, Yosuke ^a,b   Sekine, Hidekazu ^a   Dobashi, Izumi ^a   Yamato, Masayuki ^a   Umezu, Mitsuo ^c   Shimizu, Tatsuya ^a   Okano, Teruo ^a  

^a Tokyo Women s Medical University Waseda University Joint Institution for Advanced Biomedical Sciences   (Japan)

^b TERUMO CORPORATION   (Japan)

^c WASEDA UNIVERSITY   (Japan)

Author keywords

angiogenesis; cardiac tissue engineering; cell sheet; engraftment; in vivo imaging; vascularization

Indexed keywords

BLOOD VESSELS; CELL ENGINEERING; COPYRIGHTS; ENDOTHELIAL CELLS; GENES; IMAGING SYSTEMS; TISSUE; TISSUE ENGINEERING;

ANGIOGENESIS; CARDIAC TISSUE ENGINEERING; CELL SHEET; CELL SUSPENSION; CLINICAL STUDY; ENGRAFTMENT; IN-VIVO; IN-VIVO IMAGING; PRECLINICAL STUDIES; VASCULARIZATION;

CELL CULTURE;

MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOLUMINESCENCE; CELL MIGRATION; CELL PROLIFERATION; CELL SHEET; CELL STRUCTURE; CELL SURVIVAL; CELL SUSPENSION; CONTROLLED STUDY; ERYTHROCYTE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NEWBORN; NONHUMAN; PERICYTE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TUNEL ASSAY; VASCULARIZATION;

EID: 85028258449     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1854     Document Type: Article

References (37)

1. Adams RH, Alitalo K. 2007; Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 8: 464–478.
2. Ara T, Tokoyoda K, Okamoto R, et al. 2005; The role of CXCL12 in the organ-specific process of artery formation. Blood 105: 3155–3161.
3. Bergers G, Brekken R, McMahon G, et al. 2000; Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2: 737–744.
4. Bussolino F, Wang J, Defilippi P, et al. 1989; Granulocyte- and granulocyte–macrophage colony-stimulating factors induce human ECs to migrate and proliferate. Nature 337: 471–473.
5. Bussolino F, Ziche M, Wang JM, et al. 1991; In vitro and in vivo activation of ECs by colony-stimulating factors. J Clin Invest 87: 986–995.
6. Cao R, Bråkenhielm E, Pawliuk R, et al. 2003; Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat Med 9: 604–613.
7. Cross MJ, Claesson-Welsh L. 2001; FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 22: 201–207.
8. Durrani S, Konoplyannikov M, Ashraf M, et al. 2010; Skeletal myoblasts for cardiac repair. Regen Med 5: 919–932.
9. Fraisl P, Mazzone M, Schmidt T, et al. 2009; Regulation of angiogenesis by oxygen and metabolism. Dev Cell 16: 167–179.
10. Grunewald M, Avraham I, Dor Y, et al. 2006; VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell 124: 175–189.
11. Hakamata Y, Murakami T, Kobayashi E. 2006; 'Firefly rats' as an organ/cellular source for long-term in vivo bioluminescent imaging. Transplantation 81: 1179–1184.
12. Hawighorst T, Skobe M, Streit M. 2002; Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth. Am J Pathol 160: 1381–1392.
13. Hellberg C, Ostman A, Heldin C. 2010; PDGF and vessel maturation. In Angiogenesis Inhibition, Liersch R, Berdel WE, Kessler T (eds). Springer: Berlin, Heidelberg; 103–114.
14. Korpisalo P, Karvinen H, Rissanen TT, et al. 2008; Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels. Circ Res 103: 1092–1099.
15. Laflamme M, Chen KY, Naumova AV, et al. 2007; Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25: 1015–1024.
16. Makkar RR, Smith RR, Cheng K, et al. 2012; Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 6736: 1–10.
17. Mann BK, West JL. 2001; Tissue engineering in the cardiovascular system: progress toward a tissue engineered heart. Anat Rec 263: 367–371.
18. Miyagawa S, Sawa Y, Sakakida S, et al. 2005; Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium. Transplantation 80: 1586–1595.
19. Nelson TJ, Martinez-Fernandez A, Yamada S, et al. 2009; Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 120: 408–416.
20. Orlic D, Kajstura J, Chimenti S, et al. 2001; Bone marrow stem cells regenerate infarcted myocardium. Nature 410: 701–705.
21. Passier R, Van Laake LW, Mummery CL. 2008; Stem-cell-based therapy and lessons from the heart. Nature 453: 322–329.
22. Pfaffl MW. 2001; A new mathematical model for relative quantification in real-time RT–PCR. Nucleic Acids Res 29: 2002–2007.
23. Reinlib L, Field L. 2000; Cell transplantation as future therapy for cardiovascular disease? A workshop of the National Heart, Lung, and Blood Institute. Circulation 101: e182–187.
24. Risau W. 1997; Mechanisms of angiogenesis. Nature 386: 671–674.
25. Segers VFM, Lee RT. 2008; Stem-cell therapy for cardiac disease. Nature 451: 937–942.
26. Sekine H, Shimizu T, Kosaka S, et al. 2006; Cardiomyocyte bridging between hearts and bioengineered myocardial tissues with mesenchymal transition of mesothelial cells. J Heart Lung Transpl 25: 324–332.
27. Sekine H, Shimizu T, Dobashi I, et al. 2011; Cardiac cell sheet transplantation improves damaged heart function via superior cell survival in comparison with dissociated cell injection. Tissue Eng A 17: 2973–2980.
28. Sekiya S, Shimizu T, Yamato M, et al. 2006; Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential. Biochem Biophys Res Commun 341: 573–582.
29. Shimizu T, Yamato M, Isoi Y, et al. 2002; Fabrication of pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ Res 90: e40–48.
30. Shimizu T, Yamato M, Kikuchi A, et al. 2003; Cell sheet engineering for myocardial tissue reconstruction. Biomaterials 24: 2309–2316.
31. Shimizu T, Sekine H, Isoi Y, et al. 2006a; Long-term survival and growth of pulsatile myocardial tissue grafts engineered by the layering of cardiomyocyte sheets. Tissue Eng 12: 499–507.
32. Shimizu T, Sekine H, Yang J, et al. 2006b; Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J 20: 708–710.
33. Takagi Y, Hashimoto N, Phan SH, et al. 2009; Erythromycin-induced CXCR4 expression on microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol 297: L420–431.
34. Thurston G, Suri C, Smith K, et al. 2012; Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286: 2511–2514.
35. Von Tell D, Armulik A, Betsholtz C. 2006; Pericytes and vascular stability. Exp Cell Res 312: 623–629.
36. Walles T, Herden T, Haverich A, et al. 2003; Influence of scaffold thickness and scaffold composition on bioartificial graft survival. Biomaterials 24: 1233–1239.
37. Zacchigna S, Pattarini L, Zentilin L, et al. 2008; Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J Clin Invest 118: 2062–2075.