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Volumn 34, Issue 4, 2015, Pages 465-473

SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms

Author keywords

breast cancer; chromatin; differentiation; Estrogen receptor

Indexed keywords

CHROMATIN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA, HUMAN; HISTONE; SUPT6H PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 85028194690     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.558     Document Type: Article
Times cited : (43)

References (46)
  • 1
    • 33644638521 scopus 로고    scopus 로고
    • Estrogen receptors and human disease
    • Deroo BJ, Korach KS. Estrogen receptors and human disease. J Clin Invest 2006; 116: 561-570.
    • (2006) J Clin Invest , vol.116 , pp. 561-570
    • Deroo, B.J.1    Korach, K.S.2
  • 2
    • 0034485142 scopus 로고    scopus 로고
    • Estrogen receptor alpha in human breast cancer: Occurrence and significance
    • Ali S, Coombes RC. Estrogen receptor alpha in human breast cancer: occurrence and significance. J Mammary Gland Biol Neoplasia 2000; 5: 271-281.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 271-281
    • Ali, S.1    Coombes, R.C.2
  • 4
    • 84871995408 scopus 로고    scopus 로고
    • GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
    • Theodorou V, Stark R, Menon S, Carroll JS. GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility. Genome Res 2013; 23: 12-22.
    • (2013) Genome Res , vol.23 , pp. 12-22
    • Theodorou, V.1    Stark, R.2    Menon, S.3    Carroll, J.S.4
  • 5
    • 61749092693 scopus 로고    scopus 로고
    • Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes
    • Kininis M, Isaacs GD, Core LJ, Hah N, Kraus WL. Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes. Mol Cell Biol 2009; 29: 1123-1133.
    • (2009) Mol Cell Biol , vol.29 , pp. 1123-1133
    • Kininis, M.1    Isaacs, G.D.2    Core, L.J.3    Hah, N.4    Kraus, W.L.5
  • 6
    • 24644486087 scopus 로고    scopus 로고
    • The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1
    • Wittmann BM, Fujinaga K, Deng H, Ogba N, Montano MM. The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1. Oncogene 2005; 24: 5576-5588.
    • (2005) Oncogene , vol.24 , pp. 5576-5588
    • Wittmann, B.M.1    Fujinaga, K.2    Deng, H.3    Ogba, N.4    Montano, M.M.5
  • 7
    • 44149124228 scopus 로고    scopus 로고
    • Cracking the RNA polymerase II CTD code
    • Egloff S, Murphy S. Cracking the RNA polymerase II CTD code. Trends Genet 2008; 24: 280-288.
    • (2008) Trends Genet , vol.24 , pp. 280-288
    • Egloff, S.1    Murphy, S.2
  • 8
    • 52049092507 scopus 로고    scopus 로고
    • HEXIM1 regulates 17b-estradiol/estrogen receptor-a-mediated expression of cyclin d1 in mammary cells via modulation of P-TEFb
    • Ogba N, Chaplin LJ, Doughman YQ, Fujinaga K, Montano MM. HEXIM1 regulates 17b-estradiol/estrogen receptor-a-mediated expression of cyclin d1 in mammary cells via modulation of P-TEFb. Cancer Res 2008; 68: 7015-7024.
    • (2008) Cancer Res , vol.68 , pp. 7015-7024
    • Ogba, N.1    Chaplin, L.J.2    Doughman, Y.Q.3    Fujinaga, K.4    Montano, M.M.5
  • 10
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007; 128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 11
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 2007; 128: 707-719.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 12
    • 70449103609 scopus 로고    scopus 로고
    • An oestrogen-receptor-alpha-bound human chromatin interactome
    • Fullwood MJ, Liu MH, Pan YF, Liu J, Xu H, Mohamed YB et al. An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 2009; 462: 58-64.
    • (2009) Nature , vol.462 , pp. 58-64
    • Fullwood, M.J.1    Liu, M.H.2    Pan, Y.F.3    Liu, J.4    Xu, H.5    Mohamed, Y.B.6
  • 13
    • 33645820442 scopus 로고    scopus 로고
    • Transcription in four dimensions: Nuclear receptordirected initiation of gene expression
    • Métivier R, Reid G, Gannon F. Transcription in four dimensions: nuclear receptordirected initiation of gene expression. EMBO Rep 2006; 7: 161-167.
    • (2006) EMBO Rep , vol.7 , pp. 161-167
    • Métivier, R.1    Reid, G.2    Gannon, F.3
  • 15
    • 80052248649 scopus 로고    scopus 로고
    • Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B
    • Prenzel T, Begus-Nahrmann Y, Kramer F, Hennion M, Hsu C, Gorsler T et al. Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B. Cancer Res 2011; 71: 5739-5753.
    • (2011) Cancer Res , vol.71 , pp. 5739-5753
    • Prenzel, T.1    Begus-Nahrmann, Y.2    Kramer, F.3    Hennion, M.4    Hsu, C.5    Gorsler, T.6
  • 16
    • 53549112774 scopus 로고    scopus 로고
    • The histone H2Bspecific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression
    • Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N et al. The histone H2Bspecific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev 2008; 22: 2664-2676.
    • (2008) Genes Dev , vol.22 , pp. 2664-2676
    • Shema, E.1    Tirosh, I.2    Aylon, Y.3    Huang, J.4    Ye, C.5    Moskovits, N.6
  • 17
    • 84861594601 scopus 로고    scopus 로고
    • The enigmatic role of H2Bub1 in cancer
    • Johnsen SA. The enigmatic role of H2Bub1 in cancer. FEBS Lett 2012; 586: 1592-1601.
    • (2012) FEBS Lett , vol.586 , pp. 1592-1601
    • Johnsen, S.A.1
  • 18
    • 84861994785 scopus 로고    scopus 로고
    • The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells
    • Karpiuk O, Najafova Z, Kramer F, Hennion M, Galonska C, König A et al. The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Mol Cell 2012; 46: 705-713.
    • (2012) Mol Cell , vol.46 , pp. 705-713
    • Karpiuk, O.1    Najafova, Z.2    Kramer, F.3    Hennion, M.4    Galonska, C.5    König, A.6
  • 19
    • 84861968321 scopus 로고    scopus 로고
    • RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
    • Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S et al. RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol Cell 2012; 46: 662-673.
    • (2012) Mol Cell , vol.46 , pp. 662-673
    • Fuchs, G.1    Shema, E.2    Vesterman, R.3    Kotler, E.4    Wolchinsky, Z.5    Wilder, S.6
  • 20
    • 84865765333 scopus 로고    scopus 로고
    • Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation
    • Chen S, Li J, Wang D-L, Sun F-L. Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation. Cell Res 2012; 22: 1402-1405.
    • (2012) Cell Res , vol.22 , pp. 1402-1405
    • Chen, S.1    Li, J.2    Wang, D.-L.3    Sun, F.-L.4
  • 21
    • 43149122898 scopus 로고    scopus 로고
    • Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells
    • Minsky N, Shema E, Field Y, Schuster M, Segal E, Oren M. Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nature Cell Biol 2008; 10: 483-488.
    • (2008) Nature Cell Biol , vol.10 , pp. 483-488
    • Minsky, N.1    Shema, E.2    Field, Y.3    Schuster, M.4    Segal, E.5    Oren, M.6
  • 22
    • 68249128223 scopus 로고    scopus 로고
    • CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 30-end processing
    • Pirngruber J, Shchebet A, Schreiber L, Shema E, Minsky N, Chapman RD et al. CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 30-end processing. EMBO Rep 2009; 10: 894-900.
    • (2009) EMBO Rep , vol.10 , pp. 894-900
    • Pirngruber, J.1    Shchebet, A.2    Schreiber, L.3    Shema, E.4    Minsky, N.5    Chapman, R.D.6
  • 23
    • 84866157104 scopus 로고    scopus 로고
    • CDK9 and H2B monoubiquitination: A well-choreographed dance
    • Johnsen SA. CDK9 and H2B monoubiquitination: a well-choreographed dance. PLoS Genet 2012; 8: e1002860.
    • (2012) PLoS Genet , vol.8 , pp. e1002860
    • Johnsen, S.A.1
  • 24
    • 79951488010 scopus 로고    scopus 로고
    • WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription
    • Zhang F, Yu X. WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription. Mol Cell 2011; 41: 384-397.
    • (2011) Mol Cell , vol.41 , pp. 384-397
    • Zhang, F.1    Yu, X.2
  • 25
    • 33846525436 scopus 로고    scopus 로고
    • The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export
    • Yoh SM, Cho H, Pickle L, Evans RM, Jones KA. The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes Dev 2007; 21: 160-174.
    • (2007) Genes Dev , vol.21 , pp. 160-174
    • Yoh, S.M.1    Cho, H.2    Pickle, L.3    Evans, R.M.4    Jones, K.A.5
  • 26
    • 78649684166 scopus 로고    scopus 로고
    • Noncanonical tandem SH2 enables interaction of elongation factor Spt6 with RNA polymerase II
    • Diebold M-L, Loeliger E, Koch M, Winston F, Cavarelli J, Romier C. Noncanonical tandem SH2 enables interaction of elongation factor Spt6 with RNA polymerase II. J Biol Chem 2010; 285: 38389-38398.
    • (2010) J Biol Chem , vol.285 , pp. 38389-38398
    • Diebold, M.-L.1    Loeliger, E.2    Koch, M.3    Winston, F.4    Cavarelli, J.5    Romier, C.6
  • 29
    • 0029890667 scopus 로고    scopus 로고
    • Evidence that Spt6p controls chromatin structure by a direct interaction with histones
    • Bortvin A, Winston F. Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 1996; 272: 1473-1476.
    • (1996) Science , vol.272 , pp. 1473-1476
    • Bortvin, A.1    Winston, F.2
  • 30
    • 65249105512 scopus 로고    scopus 로고
    • RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
    • Kim J, Guermah M, McGinty RK, Lee J-S, Tang Z, Milne TA et al. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 2009; 137: 459-471.
    • (2009) Cell , vol.137 , pp. 459-471
    • Kim, J.1    Guermah, M.2    McGinty, R.K.3    Lee, J.-S.4    Tang, Z.5    Milne, T.A.6
  • 33
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1    Perou, C.M.2    Tibshirani, R.3    Aas, T.4    Geisler, S.5    Johnsen, H.6
  • 35
    • 54349101605 scopus 로고    scopus 로고
    • Systematic bioinformatic analysis of expression levels of 17 330 human genes across 9783 samples from 175 types of healthy and pathological tissues
    • Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H et al. Systematic bioinformatic analysis of expression levels of 17 330 human genes across 9783 samples from 175 types of healthy and pathological tissues. Genome Biol 2008; 9: R139.
    • (2008) Genome Biol , vol.9 , pp. R139
    • Kilpinen, S.1    Autio, R.2    Ojala, K.3    Iljin, K.4    Bucher, E.5    Sara, H.6
  • 36
    • 0035984714 scopus 로고    scopus 로고
    • Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
    • Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SIS et al. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotech 2002; 20: 592-596.
    • (2002) Nat Biotech , vol.20 , pp. 592-596
    • Simonsen, J.L.1    Rosada, C.2    Serakinci, N.3    Justesen, J.4    Stenderup, K.5    Rattan, S.I.S.6
  • 37
    • 33644765912 scopus 로고    scopus 로고
    • Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
    • Collett K, Eide GE, Arnes J, Stefansson IM, Eide J, Braaten A et al. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res 2006; 12: 1168-1174.
    • (2006) Clin Cancer Res , vol.12 , pp. 1168-1174
    • Collett, K.1    Eide, G.E.2    Arnes, J.3    Stefansson, I.M.4    Eide, J.5    Braaten, A.6
  • 38
    • 9144226103 scopus 로고    scopus 로고
    • Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene
    • Raaphorst FM, CJLM Meijer, Fieret E, Blokzijl T, Mommers E, Buerger H et al. Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene. Neoplasia 2003; 5: 481-488.
    • (2003) Neoplasia , vol.5 , pp. 481-488
    • Raaphorst, F.M.1    Meijer, C.J.L.M.2    Fieret, E.3    Blokzijl, T.4    Mommers, E.5    Buerger, H.6
  • 40
    • 84862622207 scopus 로고    scopus 로고
    • The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
    • Chen S, Ma J, Wu F, Xiong L-J, Ma H, Xu W et al. The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev 2012; 26: 1364-1375.
    • (2012) Genes Dev , vol.26 , pp. 1364-1375
    • Chen, S.1    Ma, J.2    Wu, F.3    Xiong, L.-J.4    Ma, H.5    Xu, W.6
  • 41
    • 84876414007 scopus 로고    scopus 로고
    • The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis
    • Wang AH, Zare H, Mousavi K, Wang C, Moravec CE, Sirotkin HI et al. The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis. EMBO J 2013; 32: 1075-1086.
    • (2013) EMBO J , vol.32 , pp. 1075-1086
    • Wang, A.H.1    Zare, H.2    Mousavi, K.3    Wang, C.4    Moravec, C.E.5    Sirotkin, H.I.6
  • 42
    • 70449915963 scopus 로고    scopus 로고
    • Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing
    • Pirngruber J, Shchebet A, Johnsen SA. Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing. Cell Cycle 2009; 8: 3636-3642.
    • (2009) Cell Cycle , vol.8 , pp. 3636-3642
    • Pirngruber, J.1    Shchebet, A.2    Johnsen, S.A.3
  • 43
    • 77952425934 scopus 로고    scopus 로고
    • Induced G1 cell-cycle arrest controls replicationdependent histone mRNA 30 end processing through p21, NPAT and CDK9
    • Pirngruber J, Johnsen SA. Induced G1 cell-cycle arrest controls replicationdependent histone mRNA 30 end processing through p21, NPAT and CDK9. Oncogene 2010; 29: 2853-2863.
    • (2010) Oncogene , vol.29 , pp. 2853-2863
    • Pirngruber, J.1    Johnsen, S.A.2
  • 44
    • 80055102133 scopus 로고    scopus 로고
    • The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair
    • Kari V, Shchebet A, Neumann H, Johnsen SA. The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair. Cell Cycle 2011; 10: 3495-3504.
    • (2011) Cell Cycle , vol.10 , pp. 3495-3504
    • Kari, V.1    Shchebet, A.2    Neumann, H.3    Johnsen, S.A.4
  • 46
    • 0034890852 scopus 로고    scopus 로고
    • Quantification of histochemical staining by color deconvolution
    • Ruifrok AC, Johnston DA. Quantification of histochemical staining by color deconvolution. Anal Quant Cytol Histol 2001; 23: 291-299
    • (2001) Anal Quant Cytol Histol , vol.23 , pp. 291-299
    • Ruifrok, A.C.1    Johnston, D.A.2


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