Preferential disruption of prefrontal GABAergic function by nanomolar concentrations of the α7nACh negative modulator kynurenic acid

Journal of Neuroscience

Volumn 37, Issue 33, 2017, Pages 7921-7929

  Flores Barrera, Eden ^a   Thomases, Daniel R ^a   Cass, Daryn K ^a   Bhandari, Ajay ^a   Schwarcz, Robert ^b   Bruno, John P ^c   Tseng, Kuei Y ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

GABA; Kynurenic acid; Local field potentials; Nicotinic receptor; Prefrontal cortex; Ventral hippocampus

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BUNGAROTOXIN RECEPTOR; KYNURENIC ACID;

ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; PREFRONTAL CORTEX; RAT; SPRAGUE DAWLEY RAT;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GABAERGIC NEURONS; INFUSIONS, INTRAVENTRICULAR; KYNURENIC ACID; MALE; ORGAN CULTURE TECHNIQUES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85028022053     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0932-17.2017     Document Type: Article

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