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Volumn 2015, Issue 9, 2015, Pages 1915-1919

A Mild and Selective Reduction of β-Lactams: Rh-Catalyzed Hydrosilylation towards Important Pharmacological Building Blocks

Author keywords

Azetidines; Hydrosilylation; Lactams; Reduction; Rhodium

Indexed keywords


EID: 85027958078     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201403655     Document Type: Article
Times cited : (18)

References (62)
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    • Selected examples:
    • Selected examples:.
  • 14
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    • H.Habashita,H.Kurata, S. Nakade andT.Ono, EP2308562A2.
    • H.Habashita,H.Kurata, S. Nakade andT.Ono, EP2308562A2, 2011.
    • (2011)
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    • .
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    • .
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    • 85128622796 scopus 로고    scopus 로고
    • See Supporting Information for full details.
    • See Supporting Information for full details.
  • 60
    • 85128653383 scopus 로고    scopus 로고
    • The easily reduced nitro, aldehyde and ketone functionalities were hydrosilylated under these conditions.
    • The easily reduced nitro, aldehyde and ketone functionalities were hydrosilylated under these conditions.
  • 61
    • 85128661121 scopus 로고    scopus 로고
    • The quenching with NH4F(aq) during workup was found to be detrimental to the isolated yield; thus, this step was omitted. Clean product was still observed by 1H and 13C NMR spectroscopy. This brought doubt over the necessity of this step for the general procedure, after initially assuming it ridded the system of excess silane that jeopardises later purification.
    • The quenching with NH4F(aq) during workup was found to be detrimental to the isolated yield; thus, this step was omitted. Clean product was still observed by 1H and 13C NMR spectroscopy. This brought doubt over the necessity of this step for the general procedure, after initially assuming it ridded the system of excess silane that jeopardises later purification.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.