Flavonoids from persimmon (Diospyros kaki L.) leaves inhibit proliferation and induce apoptosis in PC-3 cells by activation of oxidative stress and mitochondrial apoptosis

Chemico-Biological Interactions

Volumn 275, Issue , 2017, Pages 210-217

  Ding, Yan ^a   Ren, Kai ^b,c   Dong, Huanhuan ^a   Song, Fei ^a   Chen, Jing ^a   Guo, Youtian ^a   Liu, Yanshan ^a   Tao, Weijie ^a   Zhang, Yali ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b XI'AN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Apoptosis; Cytotoxicity; Flavonoids; Oxidative stress; Persimmon leaves; Prostate cancer

Indexed keywords

CYTOCHROME C; FLAVONOID; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; NITRITE; PROTEIN BAX; PROTEIN BCL 2; QUERCETIN; REACTIVE OXYGEN METABOLITE; RUTOSIDE; NITRIC OXIDE; PLANT EXTRACT;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC50; MEMBRANE PERMEABILITY; MITOCHONDRION; OXIDATIVE STRESS; PERSIMMON; PLANT LEAF; PROSTATE CANCER; UPREGULATION; CELL CYCLE CHECKPOINT; CELL MOTION; CHEMISTRY; DIOSPYROS; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; TUMOR CELL LINE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYTOCHROMES C; DIOSPYROS; FLAVONOIDS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 85027706945     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2017.07.026     Document Type: Article

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