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Volumn 23, Issue 17, 2017, Pages 5101-5111

Utility of genomic assessment of blood-derived circulating tumor DNA (ctDNA) in patients with advanced lung adenocarcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; CIRCULATING TUMOR DNA; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 85027511861     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-2497     Document Type: Article
Times cited : (124)

References (49)
  • 3
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 4
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • Liu ET, editor
    • Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. Liu ET, editor. PLoS Med 2005; 2:e73.
    • (2005) PLoS Med , vol.2 , pp. e73
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3    Riely, G.J.4    Somwar, R.5    Zakowski, M.F.6
  • 5
    • 68949201629 scopus 로고    scopus 로고
    • Activating and resistance mutations of EGFR in non-small-cell lung cancer: Role in clinical response to EGFR tyrosine kinase inhibitors
    • Gazdar AF Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors. Oncogene 2009; 28 Suppl 1:S24-31.
    • (2009) Oncogene , vol.28 , pp. S24-S31
    • Gazdar, A.F.1
  • 6
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304:1497-500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 7
    • 34547655830 scopus 로고    scopus 로고
    • Selecting patients for treatment with epidermal growth factor tyrosine kinase inhibitors
    • Bonomi PD, Buckingham L, Coon J. Selecting patients for treatment with epidermal growth factor tyrosine kinase inhibitors. Clin Cancer Res 2007; 13(15 Pt 2):s4606-12.
    • (2007) Clin Cancer Res , vol.13 , Issue.15 , pp. s4606-s4612
    • Bonomi, P.D.1    Buckingham, L.2    Coon, J.3
  • 11
    • 38049150665 scopus 로고    scopus 로고
    • MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J, Brennan C, Shih J-Y, Riely G, Viale A, Wang L, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 2007; 104:20932-7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20932-20937
    • Bean, J.1    Brennan, C.2    Shih, J.-Y.3    Riely, G.4    Viale, A.5    Wang, L.6
  • 12
    • 84984851860 scopus 로고    scopus 로고
    • Kinetic monitoring of EGFR T790M in urinary circulating tumor DNA to predict radiographic progression and response in patients with metastatic lung adenocarcinoma
    • 8081
    • Husain H, Kosco K, Rose C, Vibat T, Melnikova V, Erlander MG, et al. Kinetic monitoring of EGFR T790M in urinary circulating tumor DNA to predict radiographic progression and response in patients with metastatic lung adenocarcinoma. J Clin Oncol 2015; 33(suppl; abstr 8081). Available from: http://meetinglibrary.asco.org/content/151073-156.
    • (2015) J Clin Oncol , vol.33
    • Husain, H.1    Kosco, K.2    Rose, C.3    Vibat, T.4    Melnikova, V.5    Erlander, M.G.6
  • 13
    • 84906250256 scopus 로고    scopus 로고
    • Gefitinib treatment in EGFR mutated caucasian NSCLC: Circulating-free tumor DNA as a surrogate for determination of EGFR status
    • Douillard JY, Ostoros G, Cobo M, Ciuleanu T, Cole R, McWalter G, et al. Gefitinib treatment in EGFR mutated caucasian NSCLC: circulating-free tumor DNA as a surrogate for determination of EGFR status. J Thorac Oncol 2014; 9:1345-53.
    • (2014) J Thorac Oncol , vol.9 , pp. 1345-1353
    • Douillard, J.Y.1    Ostoros, G.2    Cobo, M.3    Ciuleanu, T.4    Cole, R.5    McWalter, G.6
  • 15
    • 84906890825 scopus 로고    scopus 로고
    • Capturing intratumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: A proof-of-principle
    • De Mattos-Arruda L, Weigelt B, Cortes J, Won HH, Ng CKY, Nuciforo P, et al. Capturing intratumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle. Ann Oncol 2014; 25:1729-35.
    • (2014) Ann Oncol , vol.25 , pp. 1729-1735
    • De Mattos-Arruda, L.1    Weigelt, B.2    Cortes, J.3    Won, H.H.4    Ng, C.K.Y.5    Nuciforo, P.6
  • 16
    • 84961636991 scopus 로고    scopus 로고
    • Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay
    • Schwaederlé M, Husain H, Fanta PT, Piccioni DE, Kesari S, Schwab RB, et al. Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay. Oncotarget 2016; 7: 9707-17.
    • (2016) Oncotarget , vol.7 , pp. 9707-9717
    • Schwaederlé, M.1    Husain, H.2    Fanta, P.T.3    Piccioni, D.E.4    Kesari, S.5    Schwab, R.B.6
  • 17
    • 84949009842 scopus 로고    scopus 로고
    • Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA
    • Lanman RB, Mortimer SA, Zill OA, Sebisanovic D, Lopez R, Blau S, et al. Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA. PLoS One 2015; 10:e0140712.
    • (2015) PLoS One , vol.10 , pp. e0140712
    • Lanman, R.B.1    Mortimer, S.A.2    Zill, O.A.3    Sebisanovic, D.4    Lopez, R.5    Blau, S.6
  • 18
    • 84867276477 scopus 로고    scopus 로고
    • Interrater reliability: The kappa statistic
    • McHugh ML Interrater reliability: the kappa statistic. Biochem Medica 2012; 22:276-82.
    • (2012) Biochem Medica , vol.22 , pp. 276-282
    • McHugh, M.L.1
  • 19
  • 20
    • 84872475151 scopus 로고    scopus 로고
    • Understanding survival analysis: KaplanMeier estimate
    • Goel MK, Khanna P, Kishore J. Understanding survival analysis: KaplanMeier estimate. Int J Ayurveda Res 2010; 1:274-8.
    • (2010) Int J Ayurveda Res , vol.1 , pp. 274-278
    • Goel, M.K.1    Khanna, P.2    Kishore, J.3
  • 21
    • 84887491073 scopus 로고    scopus 로고
    • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
    • Frampton GM, Fichtenholtz A, Otto GA, Wang K, Downing SR, He J, et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol 2013; 31: 1023-31.
    • (2013) Nat Biotechnol , vol.31 , pp. 1023-1031
    • Frampton, G.M.1    Fichtenholtz, A.2    Otto, G.A.3    Wang, K.4    Downing, S.R.5    He, J.6
  • 22
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014; 511:543-50.
    • (2014) Nature , vol.511 , pp. 543-550
  • 23
    • 84866410479 scopus 로고    scopus 로고
    • Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
    • Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012; 150:1107-20.
    • (2012) Cell , vol.150 , pp. 1107-1120
    • Imielinski, M.1    Berger, A.H.2    Hammerman, P.S.3    Hernandez, B.4    Pugh, T.J.5    Hodis, E.6
  • 24
    • 65349107082 scopus 로고    scopus 로고
    • KRAS mutations in non-small cell lung cancer
    • Riely GJ, Marks J, Pao W. KRAS mutations in non-small cell lung cancer. Proc Am Thorac Soc 2009; 6:201-5.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 201-205
    • Riely, G.J.1    Marks, J.2    Pao, W.3
  • 25
    • 84975477659 scopus 로고    scopus 로고
    • Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation
    • Vigneswaran J, Tan Y-HC, Murgu SD, Won BM, Patton KA, Villaflor VM, et al. Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation. Oncotarget 2016; 7:18876-86.
    • (2016) Oncotarget , vol.7 , pp. 18876-18886
    • Vigneswaran, J.1    Tan, Y.-H.C.2    Murgu, S.D.3    Won, B.M.4    Patton, K.A.5    Villaflor, V.M.6
  • 26
  • 27
    • 84950131811 scopus 로고    scopus 로고
    • Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients
    • Kim ST, Lee W-S, Lanman RB, Mortimer S, Zill OA, Kim K-M, et al. Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients. Oncotarget 2015; 6:40360-9.
    • (2015) Oncotarget , vol.6 , pp. 40360-40369
    • Kim, S.T.1    Lee, W.-S.2    Lanman, R.B.3    Mortimer, S.4    Zill, O.A.5    Kim, K.-M.6
  • 28
    • 84930025659 scopus 로고    scopus 로고
    • Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies
    • Janku F, Angenendt P, Tsimberidou AM, Fu S, Naing A, Falchook GS, et al. Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget 2015; 6: 12809-21.
    • (2015) Oncotarget , vol.6 , pp. 12809-12821
    • Janku, F.1    Angenendt, P.2    Tsimberidou, A.M.3    Fu, S.4    Naing, A.5    Falchook, G.S.6
  • 29
    • 85006312500 scopus 로고    scopus 로고
    • Detection of therapeutically targetable driver and resistance mutations in lung cancer patients by next-generation sequencing of cell-free circulating tumor DNA
    • Thompson JC, Yee SS, Troxel AB, Savitch SL, Fan R, Balli D, et al. Detection of therapeutically targetable driver and resistance mutations in lung cancer patients by next-generation sequencing of cell-free circulating tumor DNA. Clin Cancer Res 2016; 22:5772-82.
    • (2016) Clin Cancer Res , vol.22 , pp. 5772-5782
    • Thompson, J.C.1    Yee, S.S.2    Troxel, A.B.3    Savitch, S.L.4    Fan, R.5    Balli, D.6
  • 31
    • 84953359146 scopus 로고    scopus 로고
    • Cell-free DNA as a molecular tool for monitoring disease progression and response to therapy in breast cancer patients
    • Liang DH, Ensor JE, Liu Z-B, Patel A, Patel TA, Chang JC, et al. Cell-free DNA as a molecular tool for monitoring disease progression and response to therapy in breast cancer patients. Breast Cancer Res Treat 2016; 155:139-49.
    • (2016) Breast Cancer Res Treat , vol.155 , pp. 139-149
    • Liang, D.H.1    Ensor, J.E.2    Liu, Z.-B.3    Patel, A.4    Patel, T.A.5    Chang, J.C.6
  • 32
    • 85007391933 scopus 로고    scopus 로고
    • Phase 1B study of vemurafenib in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with BRAF V600E mutation
    • Hong DS, Morris VK, El Osta B, Sorokin AV, Janku F, Fu S, et al. Phase 1B study of vemurafenib in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with BRAF V600E mutation. Cancer Discov 2016; 6:1352-65.
    • (2016) Cancer Discov , vol.6 , pp. 1352-1365
    • Hong, D.S.1    Morris, V.K.2    El Osta, B.3    Sorokin, A.V.4    Janku, F.5    Fu, S.6
  • 33
    • 85009135117 scopus 로고    scopus 로고
    • Real-time genomic characterization utilizing circulating cell-free DNA in patients with anaplastic thyroid carcinoma
    • Sandulache VC, Williams MD, Lai SY, Lu C, William WN, Busaidy NL, et al. Real-time genomic characterization utilizing circulating cell-free DNA in patients with anaplastic thyroid carcinoma. Thyroid 2017; 27:81-7.
    • (2017) Thyroid , vol.27 , pp. 81-87
    • Sandulache, V.C.1    Williams, M.D.2    Lai, S.Y.3    Lu, C.4    William, W.N.5    Busaidy, N.L.6
  • 34
    • 84994910404 scopus 로고    scopus 로고
    • Somatic genomic landscape of over 15,000 patients with advanced-stage cancer from clinical next-generation sequencing analysis of circulating tumor DNA
    • LBA11501 Jun
    • Zill OA, Mortimer SA, Banks KC, Nagy RJ, Chudova D, Jackson C, et al. Somatic genomic landscape of over 15,000 patients with advanced-stage cancer from clinical next-generation sequencing analysis of circulating tumor DNA. Abstract LBA11501. J Clin Oncol [Internet] 2016 Jun; 34 (18 suppl). Available from: http://bit.ly/2biymcr.
    • (2016) J Clin Oncol [Internet] , vol.34 , Issue.18
    • Zill, O.A.1    Mortimer, S.A.2    Banks, K.C.3    Nagy, R.J.4    Chudova, D.5    Jackson, C.6
  • 35
    • 85014739217 scopus 로고    scopus 로고
    • Polyclonal secondary FGFR2 mutations drive acquired resistance to FGFR inhibition in patients with FGFR2 fusion-positive cholangiocarcinoma
    • Goyal L, Saha SK, Liu LY, Siravegna G, Leshchiner I, Ahronian LG, et al. Polyclonal secondary FGFR2 mutations drive acquired resistance to FGFR inhibition in patients with FGFR2 fusion-positive cholangiocarcinoma. Cancer Discov 2017; 7:252-63.
    • (2017) Cancer Discov , vol.7 , pp. 252-263
    • Goyal, L.1    Saha, S.K.2    Liu, L.Y.3    Siravegna, G.4    Leshchiner, I.5    Ahronian, L.G.6
  • 36
    • 85015291158 scopus 로고    scopus 로고
    • Clinical impact of hybrid capture-based next-generation sequencing on changes in treatment decisions in lung cancer
    • Rozenblum AB, Ilouze M, Dudnik E, Dvir A, Soussan-Gutman L, Geva S, et al. Clinical impact of hybrid capture-based next-generation sequencing on changes in treatment decisions in lung cancer. J Thorac Oncol 2017; 12:258-68.
    • (2017) J Thorac Oncol , vol.12 , pp. 258-268
    • Rozenblum, A.B.1    Ilouze, M.2    Dudnik, E.3    Dvir, A.4    Soussan-Gutman, L.5    Geva, S.6
  • 38
    • 84949205332 scopus 로고    scopus 로고
    • EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291
    • Thress KS, Brant R, Carr TH, Dearden S, Jenkins S, Brown H, et al. EGFR mutation detection in ctDNA from NSCLC patient plasma: a cross-platform comparison of leading technologies to support the clinical development of AZD9291. Lung Cancer Amst Neth 2015; 90:509-15.
    • (2015) Lung Cancer Amst Neth , vol.90 , pp. 509-515
    • Thress, K.S.1    Brant, R.2    Carr, T.H.3    Dearden, S.4    Jenkins, S.5    Brown, H.6
  • 40
    • 84946208882 scopus 로고    scopus 로고
    • Impact of a bio marker-based strategy on oncology drug development: A meta-analysis of clinical trials leading to FDA approval
    • pii: djv253
    • Fontes Jardim DL, Schwaederle M, Wei C, Lee JJ, Hong DS, Eggermont AM, et al. Impact of a bio marker-based strategy on oncology drug development: a meta-analysis of clinical trials leading to FDA approval. J Natl Cancer Inst 2015; 107, pii: djv253. doi:10.1093/jnci/djv253.
    • (2015) J Natl Cancer Inst , vol.107
    • Fontes Jardim, D.L.1    Schwaederle, M.2    Wei, C.3    Lee, J.J.4    Hong, D.S.5    Eggermont, A.M.6
  • 41
  • 42
    • 84992138510 scopus 로고    scopus 로고
    • Association of bio marker-based treatment strategies with response rates and progression-free survival in refractory Malignant neoplasms: A metaanalysis
    • Schwaederle M, Zhao M, Lee JJ, Lazar V, Leyland-Jones B, Schilsky RL, et al. Association of bio marker-based treatment strategies with response rates and progression-free survival in refractory malignant neoplasms: a metaanalysis. JAMA Oncol 2016; 2:1452-9.
    • (2016) JAMA Oncol , vol.2 , pp. 1452-1459
    • Schwaederle, M.1    Zhao, M.2    Lee, J.J.3    Lazar, V.4    Leyland-Jones, B.5    Schilsky, R.L.6
  • 44
    • 84991234522 scopus 로고    scopus 로고
    • Clinical mutational profiling of bone metastases of lung and colon carcinoma and Malignant melanoma using next-generation sequencing
    • Zheng G, Lin M-T, Lokhandwala PM, Beierl K, Netto GJ, Gocke CD, et al. Clinical mutational profiling of bone metastases of lung and colon carcinoma and malignant melanoma using next-generation sequencing. Cancer 2016; 124:744-53.
    • (2016) Cancer , vol.124 , pp. 744-753
    • Zheng, G.1    Lin, M.-T.2    Lokhandwala, P.M.3    Beierl, K.4    Netto, G.J.5    Gocke, C.D.6
  • 45
    • 84959039844 scopus 로고    scopus 로고
    • Monitoring EGFRT790M with plasma DNA from lung cancer patients in a prospective observational study
    • Sueoka-Aragane N, Katakami N, Satouchi M, Yokota S, Aoe K, Iwanaga K, et al. Monitoring EGFRT790M with plasma DNA from lung cancer patients in a prospective observational study. Cancer Sci 2016; 107:162-7.
    • (2016) Cancer Sci , vol.107 , pp. 162-167
    • Sueoka-Aragane, N.1    Katakami, N.2    Satouchi, M.3    Yokota, S.4    Aoe, K.5    Iwanaga, K.6
  • 46
    • 85028832633 scopus 로고    scopus 로고
    • Contribution of KRAS mutations and c.2369C >T (p. T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: A study on circulating tumor DNA
    • Del Re M, Tiseo M, Bordi P, D'Incecco A, Camerini A, Petrini I, et al. Contribution of KRAS mutations and c.2369C >T (p. T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA. Oncotarget 2017; 8:13611-9.
    • (2017) Oncotarget , vol.8 , pp. 13611-13619
    • Del Re, M.1    Tiseo, M.2    Bordi, P.3    D'Incecco, A.4    Camerini, A.5    Petrini, I.6
  • 47
    • 84961204150 scopus 로고    scopus 로고
    • EGFR mutation status in plasma and tumor tissues in non-small cell lung cancer serves as a predictor of response to EGFR-TKI treatment
    • Que D, Xiao H, Zhao B, Zhang X, Wang Q, Xiao H, et al. EGFR mutation status in plasma and tumor tissues in non-small cell lung cancer serves as a predictor of response to EGFR-TKI treatment. Cancer Biol Ther 2016; 17: 320-7.
    • (2016) Cancer Biol Ther , vol.17 , pp. 320-327
    • Que, D.1    Xiao, H.2    Zhao, B.3    Zhang, X.4    Wang, Q.5    Xiao, H.6
  • 49
    • 84942521554 scopus 로고    scopus 로고
    • Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches
    • Drilon A, Wang L, Arcila ME, Balasubramanian S, Greenbowe JR, Ross JS, et al. Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other genomic testing approaches. Clin Cancer Res 2015; 21:3631-9.
    • (2015) Clin Cancer Res , vol.21 , pp. 3631-3639
    • Drilon, A.1    Wang, L.2    Arcila, M.E.3    Balasubramanian, S.4    Greenbowe, J.R.5    Ross, J.S.6


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