-
1
-
-
84925234844
-
Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology
-
Masters GA, Krilov L, Bailey HH, Brose MS, Burstein H, Diller LR, et al. Clinical cancer advances 2015: annual report on progress against cancer from the American Society of Clinical Oncology. J Clin Oncol 2015;33:786-809.
-
(2015)
J Clin Oncol
, vol.33
, pp. 786-809
-
-
Masters, G.A.1
Krilov, L.2
Bailey, H.H.3
Brose, M.S.4
Burstein, H.5
Diller, L.R.6
-
2
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 2012;486:405-9.
-
(2012)
Nature
, vol.486
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
Brown, K.K.4
Carter, S.L.5
Frederick, A.M.6
-
3
-
-
77955090106
-
Subtype-specific genomic alterations define new targets for softtissue sarcoma therapy
-
Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, et al. Subtype-specific genomic alterations define new targets for softtissue sarcoma therapy. Nat Genet 2010;42:715-21.
-
(2010)
Nat Genet
, vol.42
, pp. 715-721
-
-
Barretina, J.1
Taylor, B.S.2
Banerji, S.3
Ramos, A.H.4
Lagos-Quintana, M.5
Decarolis, P.L.6
-
4
-
-
84878302099
-
Gene expression classification of colon cancer into molecular subtypes: Characterization, validation, and prognostic value
-
Marisa L, de Reyniés A, Duval A, Selves J, Gaub MP, Vescovo L, et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med 2013;10:e1001453.
-
(2013)
PLoS Med
, vol.10
, pp. e1001453
-
-
Marisa, L.1
De Reyniés, A.2
Duval, A.3
Selves, J.4
Gaub, M.P.5
Vescovo, L.6
-
5
-
-
84898004715
-
Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes
-
Walter V, Yin X, Wilkerson MD, Cabanski CR, Zhao N, Du Y, et al. Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes. PLoS ONE 2013;8:e56823.
-
(2013)
PLoS ONE
, vol.8
, pp. e56823
-
-
Walter, V.1
Yin, X.2
Wilkerson, M.D.3
Cabanski, C.R.4
Zhao, N.5
Du, Y.6
-
6
-
-
84908460595
-
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
-
Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell 2014;158:929-44.
-
(2014)
Cell
, vol.158
, pp. 929-944
-
-
Hoadley, K.A.1
Yau, C.2
Wolf, D.M.3
Cherniack, A.D.4
Tamborero, D.5
Ng, S.6
-
7
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
8
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005;2:e73.
-
(2005)
PLoS Med
, vol.2
, pp. e73
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
-
9
-
-
84873974299
-
Crizotinib: A new treatment option for ALK-positive non-small cell lung cancer
-
O'Bryant CL, Wenger SD, Kim M, Thompson LA. Crizotinib: a new treatment option for ALK-positive non-small cell lung cancer. Ann Pharmacother 2013;47:189-97.
-
(2013)
Ann Pharmacother
, vol.47
, pp. 189-197
-
-
O'Bryant, C.L.1
Wenger, S.D.2
Kim, M.3
Thompson, L.A.4
-
10
-
-
84862999938
-
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
-
Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 2012;486:532-6.
-
(2012)
Nature
, vol.486
, pp. 532-536
-
-
Misale, S.1
Yaeger, R.2
Hobor, S.3
Scala, E.4
Janakiraman, M.5
Liska, D.6
-
11
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
Verma S, Miles D, Gianni L, Krop IE, Welslau M, Baselga J, et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med 2012;367:1783-91.
-
(2012)
N Engl J Med
, vol.367
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
Krop, I.E.4
Welslau, M.5
Baselga, J.6
-
12
-
-
84891364722
-
Assessment of HER2 status in breast cancer: Overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: A quality control study
-
Varga Z, Noske A, Ramach C, Padberg B, Moch H. Assessment of HER2 status in breast cancer: overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: a quality control study. BMC Cancer 2013;13:615.
-
(2013)
BMC Cancer
, vol.13
, pp. 615
-
-
Varga, Z.1
Noske, A.2
Ramach, C.3
Padberg, B.4
Moch, H.5
-
13
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011;364:2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
14
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
-
Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau TH, Brown MP, et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 19;379:1893-901.
-
Lancet
, vol.19
, Issue.379
, pp. 1893-1901
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
Kim, K.B.4
Arkenau, T.H.5
Brown, M.P.6
-
15
-
-
31144453233
-
BRAF mutation predicts sensitivity to MEK inhibition
-
Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature 2006;439:358-62.
-
(2006)
Nature
, vol.439
, pp. 358-362
-
-
Solit, D.B.1
Garraway, L.A.2
Pratilas, C.A.3
Sawai, A.4
Getz, G.5
Basso, A.6
-
16
-
-
84937990975
-
On the road to precision cancer medicine: Analysis of genomic biomarker actionability in 439 patients
-
Schwaederle M, Daniels GA, Piccioni DE, Fanta PT, Schwab RB, Shimabukuro KA, et al. On the road to precision cancer medicine: analysis of genomic biomarker actionability in 439 patients. Mol Cancer Ther 2015;14:1488-94.
-
(2015)
Mol Cancer Ther
, vol.14
, pp. 1488-1494
-
-
Schwaederle, M.1
Daniels, G.A.2
Piccioni, D.E.3
Fanta, P.T.4
Schwab, R.B.5
Shimabukuro, K.A.6
-
17
-
-
84947216680
-
Breast cancer experience of the molecular Tumor Board at the University of California, San Diego
-
Parker BA, Schwaederlé M, Scur MD, Boles SG, Helsten T, Subramanian R, et al. Breast cancer experience of the molecular Tumor Board at the University of California, San Diego. J Oncol Pract 2015;11:442-9.
-
(2015)
J Oncol Pract
, vol.11
, pp. 442-449
-
-
Parker, B.A.1
Schwaederlé, M.2
Scur, M.D.3
Boles, S.G.4
Helsten, T.5
Subramanian, R.6
-
18
-
-
84901918076
-
Molecular tumor board: The University of California-San Diego Moores Cancer Center experience
-
Schwaederle M, Parker BA, Schwab RB, Fanta PT, Boles SG, Daniels GA, et al. Molecular tumor board: the University of California-San Diego Moores Cancer Center experience. Oncologist 2014;19:631-6.
-
(2014)
Oncologist
, vol.19
, pp. 631-636
-
-
Schwaederle, M.1
Parker, B.A.2
Schwab, R.B.3
Fanta, P.T.4
Boles, S.G.5
Daniels, G.A.6
-
19
-
-
84861133847
-
Survival of 1, 181 patients in a phase I clinic: TheMDAnderson Clinical Center for targeted therapy experience
-
Wheler J, Tsimberidou AM, Hong D, Naing A, Falchook G, Piha-Paul S, et al. Survival of 1, 181 patients in a phase I clinic: the MD Anderson Clinical Center for targeted therapy experience. Clin Cancer Res 2012;18:2922-9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2922-2929
-
-
Wheler, J.1
Tsimberidou, A.M.2
Hong, D.3
Naing, A.4
Falchook, G.5
Piha-Paul, S.6
-
20
-
-
84900829967
-
USing multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
-
Kris MG, Johnson BE, Berry LD, et al. USing multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014;311:1998-2006.
-
(2014)
JAMA
, vol.311
, pp. 1998-2006
-
-
Kris, M.G.1
Johnson, B.E.2
Berry, L.D.3
-
21
-
-
0034650624
-
Categorizing a prognostic variable: Review of methods, code for easy implementation and applications to decisionmaking about cancer treatments
-
Mazumdar M, Glassman JR. Categorizing a prognostic variable: review of methods, code for easy implementation and applications to decisionmaking about cancer treatments. Stat Med 2000;19:113-32.
-
(2000)
Stat Med
, vol.19
, pp. 113-132
-
-
Mazumdar, M.1
Glassman, J.R.2
-
22
-
-
79951906119
-
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers
-
Von Hoff DD, Stephenson JJ Jr, Rosen P, Loesch DM, Borad MJ, Anthony S, et al. Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 2010;28:4877-83.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4877-4883
-
-
Von Hoff, D.D.1
Stephenson, J.J.2
Rosen, P.3
Loesch, D.M.4
Borad, M.J.5
Anthony, S.6
-
23
-
-
63449116467
-
Alternate endpoints for screening phase II studies
-
Dhani N, Tu D, Sargent DJ, Seymour L, Moore MJ. Alternate endpoints for screening phase II studies. Clin Cancer Res 2009;15:1873-82.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1873-1882
-
-
Dhani, N.1
Tu, D.2
Sargent, D.J.3
Seymour, L.4
Moore, M.J.5
-
24
-
-
84872475151
-
Understanding survival analysis: Kaplan-Meier estimate
-
Goel MK, Khanna P, Kishore J. Understanding survival analysis: Kaplan-Meier estimate. Int J Ayurveda Res 2010;1:274-8.
-
(2010)
Int J Ayurveda Res
, vol.1
, pp. 274-278
-
-
Goel, M.K.1
Khanna, P.2
Kishore, J.3
-
25
-
-
84943780413
-
Next-generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer
-
Schwaederle M, Daniels GA, Piccioni DE, Kesari S, Fanta PT, Schwab RB, et al. Next-generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer. Cell Cycle 2015;14:1730-7.
-
(2015)
Cell Cycle
, vol.14
, pp. 1730-1737
-
-
Schwaederle, M.1
Daniels, G.A.2
Piccioni, D.E.3
Kesari, S.4
Fanta, P.T.5
Schwab, R.B.6
-
26
-
-
84896729825
-
The use of propensity score methods with survival or time-toevent outcomes: Reporting measures of effect similar to those used in randomized experiments
-
Austin PC. The use of propensity score methods with survival or time-toevent outcomes: reporting measures of effect similar to those used in randomized experiments. Stat Med 2014;33:1242-58.
-
(2014)
Stat Med
, vol.33
, pp. 1242-1258
-
-
Austin, P.C.1
-
27
-
-
79958704133
-
An introduction to propensity score methods for reducing the effects of confounding in observational studies
-
Austin PC. An introduction to propensity score methods for reducing the effects of confounding in observational studies. Multivar Behav Res 2011;46:399-424.
-
(2011)
Multivar Behav Res
, vol.46
, pp. 399-424
-
-
Austin, P.C.1
-
28
-
-
79951791644
-
A tutorial and case study in propensity score analysis: An application to estimating the effect of in-hospital smoking cessation counseling on mortality
-
Austin PC. A tutorial and case study in propensity score analysis: an application to estimating the effect of in-hospital smoking cessation counseling on mortality. Multivar Behav Res 2011;46:119-51.
-
(2011)
Multivar Behav Res
, vol.46
, pp. 119-151
-
-
Austin, P.C.1
-
29
-
-
84900031607
-
A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: Implications for clinical practice
-
Vasan N, Yelensky R, Wang K, Moulder S, Dzimitrowicz H, Avritscher R, et al. A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: implications for clinical practice. Oncologist 2014;19:453-8.
-
(2014)
Oncologist
, vol.19
, pp. 453-458
-
-
Vasan, N.1
Yelensky, R.2
Wang, K.3
Moulder, S.4
Dzimitrowicz, H.5
Avritscher, R.6
-
30
-
-
84928215463
-
Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients
-
Wong SQ, Fellowes A, Doig K, Ellul J, Bosma TJ, Irwin D, et al. Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients. Br J Cancer 2015;112:1411-20.
-
(2015)
Br J Cancer
, vol.112
, pp. 1411-1420
-
-
Wong, S.Q.1
Fellowes, A.2
Doig, K.3
Ellul, J.4
Bosma, T.J.5
Irwin, D.6
-
31
-
-
84869223443
-
Personalized medicine in a phase I clinical trials program: The MD Anderson Cancer Center initiative
-
Tsimberidou A-M, Iskander NG, Hong DS, Wheler JJ, Falchook GS, Fu S, et al. Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative. Clin Cancer Res Off J Am Assoc Cancer Res 2012;18:6373-83.
-
(2012)
Clin Cancer Res Off J Am Assoc Cancer Res
, vol.18
, pp. 6373-6383
-
-
Tsimberidou, A.-M.1
Iskander, N.G.2
Hong, D.S.3
Wheler, J.J.4
Falchook, G.S.5
Fu, S.6
-
32
-
-
84910651190
-
A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer
-
Jameson GS, Petricoin EF, Sachdev J, Liotta LA, Loesch DM, Anthony SP, et al. A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer. Breast Cancer Res Treat 2014;147:579-88.
-
(2014)
Breast Cancer Res Treat
, vol.147
, pp. 579-588
-
-
Jameson, G.S.1
Petricoin, E.F.2
Sachdev, J.3
Liotta, L.A.4
Loesch, D.M.5
Anthony, S.P.6
-
33
-
-
84954026435
-
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): A multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
-
Le Tourneau C, Delord J-P, Gonçalves A, Gavoille C, Dubot C, Isambert N, et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet Oncol 2015;16:1324-34.
-
(2015)
Lancet Oncol
, vol.16
, pp. 1324-1334
-
-
Le Tourneau, C.1
Delord, J.-P.2
Gonçalves, A.3
Gavoille, C.4
Dubot, C.5
Isambert, N.6
-
34
-
-
84901936604
-
Enabling a genetically informed approach to cancer medicine: A retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel
-
Johnson DB, Dahlman KH, Knol J, Gilbert J, Puzanov I, Means-Powell J, et al. Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel. Oncologist 2014;19:616-22.
-
(2014)
Oncologist
, vol.19
, pp. 616-622
-
-
Johnson, D.B.1
Dahlman, K.H.2
Knol, J.3
Gilbert, J.4
Puzanov, I.5
Means-Powell, J.6
-
35
-
-
84939864059
-
Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations
-
Hyman DM, Puzanov I, Subbiah V, Faris JE, Chau I, Blay J-Y, et al. Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations. N Engl J Med 2015;373:726-36.
-
(2015)
N Engl J Med
, vol.373
, pp. 726-736
-
-
Hyman, D.M.1
Puzanov, I.2
Subbiah, V.3
Faris, J.E.4
Chau, I.5
Blay, J.-Y.6
-
36
-
-
84946053976
-
Impact of precision medicine in diverse cancers: A meta-analysis of phase II clinical trials
-
Schwaederle M, Zhao M, Lee JJ, Eggermont AM, Schilsky RL, Mendelsohn J, et al. Impact of precision medicine in diverse cancers: a meta-analysis of phase II clinical trials. J Clin Oncol 2015;33:3817-25.
-
(2015)
J Clin Oncol
, vol.33
, pp. 3817-3825
-
-
Schwaederle, M.1
Zhao, M.2
Lee, J.J.3
Eggermont, A.M.4
Schilsky, R.L.5
Mendelsohn, J.6
-
37
-
-
84946208882
-
Impact of a biomarker-based strategy on oncology drug development: Ameta-analysis of clinical trials leading to FDA approval
-
Fontes Jardim DL, Schwaederle M, Wei C, Lee JJ, Hong DS, Eggermont AM, et al. Impact of a biomarker-based strategy on oncology drug development: ameta-analysis of clinical trials leading to FDA approval. J Natl Cancer Inst 2015;107.
-
(2015)
J Natl Cancer Inst
, pp. 107
-
-
Fontes Jardim, D.L.1
Schwaederle, M.2
Wei, C.3
Lee, J.J.4
Hong, D.S.5
Eggermont, A.M.6
-
38
-
-
84903881484
-
CAn the learning health care system be educated with observational data?
-
Dahabreh IJ, Kent DM. CAn the learning health care system be educated with observational data? JAMA 2014;312:129-30.
-
(2014)
JAMA
, vol.312
, pp. 129-130
-
-
Dahabreh, I.J.1
Kent, D.M.2
-
39
-
-
84888767796
-
Integrated molecular portrait of non-small cell lung cancers
-
Lazar V, Suo C, Orear C, van den Oord J, Balogh Z, Guegan J, et al. Integrated molecular portrait of non-small cell lung cancers. BMC Med Genomics 2013;6:53.
-
(2013)
BMC Med Genomics
, vol.6
, pp. 53
-
-
Lazar, V.1
Suo, C.2
Orear, C.3
Van Den Oord, J.4
Balogh, Z.5
Guegan, J.6
-
40
-
-
84931037125
-
A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer
-
Lazar V, Rubin E, Depil S, Pawitan Y, Martini J-F, Gomez-Navarro J, et al. A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer. Oncotarget 2015;6:14139-52.
-
(2015)
Oncotarget
, vol.6
, pp. 14139-14152
-
-
Lazar, V.1
Rubin, E.2
Depil, S.3
Pawitan, Y.4
Martini, J.-F.5
Gomez-Navarro, J.6
-
41
-
-
84895906492
-
Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors
-
Janku F, Hong DS, Fu S, Piha-Paul SA, Naing A, Falchook GS, et al. Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors. Cell Rep 2014;6:377-87.
-
(2014)
Cell Rep
, vol.6
, pp. 377-387
-
-
Janku, F.1
Hong, D.S.2
Fu, S.3
Piha-Paul, S.A.4
Naing, A.5
Falchook, G.S.6
|