Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies

Oncotarget

Volumn 6, Issue 14, 2015, Pages 12809-12821

  Janku, Filip ^a   Angenendt, Philipp ^b   Tsimberidou, Apostolia M ^a   Fu, Siqing ^a   Naing, Aung ^a   Falchook, Gerald S ^a   Hong, David S ^a   Holley, Veronica R ^a   Cabrilo, Goran ^a   Wheler, Jennifer J ^a   Piha Paul, Sarina A ^a   Zinner, Ralph G ^a   Bedikian, Agop Y ^a   Overman, Michael J ^a   Kee, Bryan K ^a   Kim, Kevin B ^a   Scott Kopetz, E ^a   Luthra, Rajyalakshmi ^a   Diehl, Frank ^b   Meric Bernstam, Funda ^a   Kurzrock, Razelle ^a,c   more..

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b SYSMEX CORPORATION   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

BRAF; Cell free DNA; EGFR; KRAS; PIK3CA

Indexed keywords

B RAF KINASE; CELL FREE DNA; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG; BRAF PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN; PROTEIN P21; TUMOR MARKER;

ADULT; ADVANCED CANCER; AGED; APPENDIX CANCER; ARTICLE; BLOOD SAMPLING; BRAF GENE; BREAST CANCER; CANCER SURVIVAL; CANCER TISSUE; COLORECTAL CANCER; DNA DETERMINATION; DRUG TARGETING; EGFR GENE; ESOPHAGUS CANCER; FEMALE; GENE; GENE FREQUENCY; GENE MUTATION; HEAD AND NECK CANCER; HUMAN; HUMAN TISSUE; KRAS GENE; MAJOR CLINICAL STUDY; MALE; MELANOMA; OVARY CANCER; OVERALL SURVIVAL; PIK3CA GENE; PROSTATE CANCER; SENSITIVITY AND SPECIFICITY; SOFT TISSUE SARCOMA; THYROID CARCINOMA; UTERUS CANCER; BLOOD; DNA MUTATIONAL ANALYSIS; GENETICS; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; NEOPLASM; PROTO ONCOGENE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENES, ERBB-1; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); YOUNG ADULT;

EID: 84930025659     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3373     Document Type: Article

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