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Volumn 9, Issue 402, 2017, Pages

Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY;

EID: 85027403406     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaf1483     Document Type: Article
Times cited : (46)

References (63)
  • 4
    • 0034864776 scopus 로고    scopus 로고
    • Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
    • P. W. H. I. Parren, P. A. Marx, A. J. Hessell, A. Luckay, J. Harouse, C. Cheng-Mayer, J. P. Moore, D. R. Burton, Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J. Virol. 75, 8340-8347 (2001).
    • (2001) J. Virol. , vol.75 , pp. 8340-8347
    • Parren, P.W.H.I.1    Marx, P.A.2    Hessell, A.J.3    Luckay, A.4    Harouse, J.5    Cheng-Mayer, C.6    Moore, J.P.7    Burton, D.R.8
  • 8
    • 84865295305 scopus 로고    scopus 로고
    • Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model
    • M. Veselinovic, C. P. Neff, L. R. Mulder, R. Akkina, Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model. Virology 432, 505-510 (2012).
    • (2012) Virology , vol.432 , pp. 505-510
    • Veselinovic, M.1    Neff, C.P.2    Mulder, L.R.3    Akkina, R.4
  • 9
    • 84937597026 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies and the development of vaccines
    • B. F. Haynes, T. Bradley, Broadly neutralizing antibodies and the development of vaccines. JAMA 313, 2419-2420 (2015).
    • (2015) JAMA , vol.313 , pp. 2419-2420
    • Haynes, B.F.1    Bradley, T.2
  • 11
    • 0020634248 scopus 로고
    • "Trojan Horse" leukocytes in AIDS
    • D. J. Anderson, E. J. Yunis, "Trojan Horse" leukocytes in AIDS. N. Engl. J. Med. 309, 984-985 (1983).
    • (1983) N. Engl. J. Med. , vol.309 , pp. 984-985
    • Anderson, D.J.1    Yunis, E.J.2
  • 12
    • 0023907540 scopus 로고
    • The transmission of AIDS: The case of the infected cell
    • J. A. Levy, The transmission of AIDS: The case of the infected cell. JAMA 259, 3037-3038 (1988).
    • (1988) JAMA , vol.259 , pp. 3037-3038
    • Levy, J.A.1
  • 14
    • 0029998895 scopus 로고    scopus 로고
    • Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission
    • T. Zhu, N. Wang, A. Carr, D. S. Nam, R. Moor-Jankowski, D. A. Cooper, D. D. Ho, Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission. J. Virol. 70, 3098-3107 (1996).
    • (1996) J. Virol. , vol.70 , pp. 3098-3107
    • Zhu, T.1    Wang, N.2    Carr, A.3    Nam, D.S.4    Moor-Jankowski, R.5    Cooper, D.A.6    Ho, D.D.7
  • 17
    • 41949101138 scopus 로고    scopus 로고
    • Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239
    • A. M. Weiler, Q. Li, L. Duan, M. Kaizu, K. L. Weisgrau, T. C. Friedrich, M. R. Reynolds, A. T. Haase, E. G. Rakasz, Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239. J. Virol. 82, 4154-4158 (2008).
    • (2008) J. Virol. , vol.82 , pp. 4154-4158
    • Weiler, A.M.1    Li, Q.2    Duan, L.3    Kaizu, M.4    Weisgrau, K.L.5    Friedrich, T.C.6    Reynolds, M.R.7    Haase, A.T.8    Rakasz, E.G.9
  • 21
    • 84887618532 scopus 로고    scopus 로고
    • Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies
    • T. Schiffner, Q. J. Sattentau, C. J. A. Duncan, Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies. Vaccine 31, 5789-5797 (2013).
    • (2013) Vaccine , vol.31 , pp. 5789-5797
    • Schiffner, T.1    Sattentau, Q.J.2    Duncan, C.J.A.3
  • 24
    • 85017538122 scopus 로고    scopus 로고
    • Reduced potency and incomplete neutralization of broadly neutralizing antibodies against cell-to-cell transmission of HIV-1 with transmitted founder Envs
    • H. Li, C. Zony, P. Chen, B. K. Chen, Reduced potency and incomplete neutralization of broadly neutralizing antibodies against cell-to-cell transmission of HIV-1 with transmitted founder Envs. J. Virol. 91, e02425-16 (2017).
    • (2017) J. Virol. , vol.91 , pp. e02425-e02516
    • Li, H.1    Zony, C.2    Chen, P.3    Chen, B.K.4
  • 29
    • 23844532213 scopus 로고    scopus 로고
    • Mucosallyadministered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3
    • S. J. Kent, C. J. Dale, C. Ranasinghe, I. Stratov, R. De Rose, S. Chea, D. C. Montefiori, S. Thomson, I. A. Ramshaw, B. E. H. Coupar, D. B. Boyle, M. Law, K. M. Wilson, A. J. Ramsay, Mucosallyadministered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3. Vaccine 23, 5009-5021 (2005).
    • (2005) Vaccine , vol.23 , pp. 5009-5021
    • Kent, S.J.1    Dale, C.J.2    Ranasinghe, C.3    Stratov, I.4    De Rose, R.5    Chea, S.6    Montefiori, D.C.7    Thomson, S.8    Ramshaw, I.A.9    Coupar, B.E.H.10    Boyle, D.B.11    Law, M.12    Wilson, K.M.13    Ramsay, A.J.14
  • 30
    • 33745726592 scopus 로고    scopus 로고
    • Comparative evaluation of simian, simian-human, and human immunodeficiency virus infections in the pigtail macaque (Macaca nemestrina) model
    • C. J. Batten, R. De Rose, K. M. Wilson, M. B. Agy, S. Chea, I. Stratov, D. C. Montefiori, S. J. Kent, Comparative evaluation of simian, simian-human, and human immunodeficiency virus infections in the pigtail macaque (Macaca nemestrina) model. AIDS Res. Hum. Retroviruses 22, 580-588 (2006).
    • (2006) AIDS Res. Hum. Retroviruses , vol.22 , pp. 580-588
    • Batten, C.J.1    De Rose, R.2    Wilson, K.M.3    Agy, M.B.4    Chea, S.5    Stratov, I.6    Montefiori, D.C.7    Kent, S.J.8
  • 36
    • 1242342134 scopus 로고    scopus 로고
    • Expansion of quasispecies diversity but no evidence for adaptive evolution of SHIV during rapid serial transfers among seronegative macaques
    • P. Balfe, S. Shapiro, M. Hsu, C. Buckner, J. M. Harouse, C. Cheng-Mayer, Expansion of quasispecies diversity but no evidence for adaptive evolution of SHIV during rapid serial transfers among seronegative macaques. Virology 318, 267-279 (2004).
    • (2004) Virology , vol.318 , pp. 267-279
    • Balfe, P.1    Shapiro, S.2    Hsu, M.3    Buckner, C.4    Harouse, J.M.5    Cheng-Mayer, C.6
  • 43
    • 84893797938 scopus 로고    scopus 로고
    • Broadly neutralizing hemagglutinin stalk-specific antibodies require FcgR interactions for protection against influenza virus in vivo
    • D. J. DiLillo, G. S. Tan, P. Palese, J. V. Ravetch, Broadly neutralizing hemagglutinin stalk-specific antibodies require FcgR interactions for protection against influenza virus in vivo. Nat. Med. 20, 143-151 (2014).
    • (2014) Nat. Med. , vol.20 , pp. 143-151
    • DiLillo, D.J.1    Tan, G.S.2    Palese, P.3    Ravetch, J.V.4
  • 44
    • 84904263611 scopus 로고    scopus 로고
    • Influenza-specific antibody-dependent cellular cytotoxicity: Toward a universal influenza vaccine
    • S. Jegaskanda, P. C. Reading, S. J. Kent, Influenza-specific antibody-dependent cellular cytotoxicity: Toward a universal influenza vaccine. J. Immunol. 193, 469-475 (2014).
    • (2014) J. Immunol. , vol.193 , pp. 469-475
    • Jegaskanda, S.1    Reading, P.C.2    Kent, S.J.3
  • 45
    • 84919458612 scopus 로고    scopus 로고
    • Slaying the Trojan Horse: Natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells
    • S. L. Gooneratne, J. Richard, W. S. Lee, A. Finzi, S. J. Kent, M. S. Parsons, Slaying the Trojan Horse: Natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells. J. Virol. 89, 97-109 (2015).
    • (2015) J. Virol. , vol.89 , pp. 97-109
    • Gooneratne, S.L.1    Richard, J.2    Lee, W.S.3    Finzi, A.4    Kent, S.J.5    Parsons, M.S.6
  • 48
    • 84927704125 scopus 로고    scopus 로고
    • Role of education and differentiation in determining the potential of natural killer cells to respond to antibody-dependent stimulation
    • M. S. Parsons, L. Loh, S. Gooneratne, R. J. Center, S. J. Kent, Role of education and differentiation in determining the potential of natural killer cells to respond to antibody-dependent stimulation. AIDS 28, 2781-2786 (2014).
    • (2014) AIDS , vol.28 , pp. 2781-2786
    • Parsons, M.S.1    Loh, L.2    Gooneratne, S.3    Center, R.J.4    Kent, S.J.5
  • 49
    • 78649587810 scopus 로고    scopus 로고
    • Killer cell immunoglobulin-like receptor 3DL1 licenses CD16-mediated effector functions of natural killer cells
    • M. S. Parsons, K. Zipperlen, M. Gallant, M. Grant, Killer cell immunoglobulin-like receptor 3DL1 licenses CD16-mediated effector functions of natural killer cells. J. Leukoc. Biol. 88, 905-912 (2010).
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 905-912
    • Parsons, M.S.1    Zipperlen, K.2    Gallant, M.3    Grant, M.4
  • 53
    • 79958863431 scopus 로고    scopus 로고
    • Selection of human anti-HIV broadly neutralizing antibodies occurs within the context of frozen 1F7-idiotypic repertoire
    • M. S. Parsons, D. Rouleau, J.-P. Routy, R. LeBlanc, M. D. Grant, N. F. Bernard, Selection of human anti-HIV broadly neutralizing antibodies occurs within the context of frozen 1F7-idiotypic repertoire. AIDS 25, 1249-1264 (2011).
    • (2011) AIDS , vol.25 , pp. 1249-1264
    • Parsons, M.S.1    Rouleau, D.2    Routy, J.-P.3    LeBlanc, R.4    Grant, M.D.5    Bernard, N.F.6
  • 54
    • 70350564956 scopus 로고    scopus 로고
    • Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens
    • R. J. Center, A. K. Wheatley, S. M. Campbell, A. J. Gaeguta, V. Peut, S. Alcantara, C. Siebentritt, S. J. Kent, D. F. J. Purcell, Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens. Vaccine 27, 6605-6612 (2009).
    • (2009) Vaccine , vol.27 , pp. 6605-6612
    • Center, R.J.1    Wheatley, A.K.2    Campbell, S.M.3    Gaeguta, A.J.4    Peut, V.5    Alcantara, S.6    Siebentritt, C.7    Kent, S.J.8    Purcell, D.F.J.9
  • 56
    • 84877317499 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques
    • S. Jegaskanda, J. T. Weinfurter, T. C. Friedrich, S. J. Kent, Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques. J. Virol. 87, 5512-5522 (2013).
    • (2013) J. Virol. , vol.87 , pp. 5512-5522
    • Jegaskanda, S.1    Weinfurter, J.T.2    Friedrich, T.C.3    Kent, S.J.4
  • 59
    • 84983751890 scopus 로고    scopus 로고
    • Dimeric FcgR ectodomains as probes of the Fc receptor function of anti-influenza virus IgG
    • B. D. Wines, H. A. Vanderven, S. E. Esparon, A. B. Kristensen, S. J. Kent, P. M. Hogarth, Dimeric FcgR ectodomains as probes of the Fc receptor function of anti-influenza virus IgG. J. Immunol. 197, 1507-1516 (2016).
    • (2016) J. Immunol. , vol.197 , pp. 1507-1516
    • Wines, B.D.1    Vanderven, H.A.2    Esparon, S.E.3    Kristensen, A.B.4    Kent, S.J.5    Hogarth, P.M.6
  • 60
    • 59749106609 scopus 로고    scopus 로고
    • Inactivated simian immunodeficiency virus-pulsed autologous fresh blood cells as an immunotherapy strategy
    • R. D. Mason, S. Alcantara, V. Peut, L. Loh, J. D. Lifson, R. De Rose, S. J. Kent, Inactivated simian immunodeficiency virus-pulsed autologous fresh blood cells as an immunotherapy strategy. J. Virol. 83, 1501-1510 (2009).
    • (2009) J. Virol. , vol.83 , pp. 1501-1510
    • Mason, R.D.1    Alcantara, S.2    Peut, V.3    Loh, L.4    Lifson, J.D.5    De Rose, R.6    Kent, S.J.7
  • 63
    • 60349089294 scopus 로고    scopus 로고
    • Measuring HIV neutralization in a luciferase reporter gene assay
    • D. C. Montefiori, Measuring HIV neutralization in a luciferase reporter gene assay. Methods Mol. Biol. 485, 395-405 (2009).
    • (2009) Methods Mol. Biol. , vol.485 , pp. 395-405
    • Montefiori, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.