CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in HBsAg transgenic mice by promoting the interaction of NKT cells with Kupffer cells

Cellular and Molecular Immunology

Volumn 14, Issue 8, 2017, Pages 675-684

  Hou, Xin ^a   Hao, Xiaolei ^b   Zheng, Meijuan ^a   Xu, Congfei ^c   Wang, Jun ^b,c   Zhou, Rongbin ^b,c   Tian, Zhigang ^b,c  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

CpG; hepatitis B virus; Kupffer cell; liver injury; NKT cell

Indexed keywords

CD205 PROTEIN; CELL SURFACE RECEPTOR; CPG OLIGODEOXYNUCLEOTIDE; FAS LIGAND; HEPATITIS B SURFACE ANTIGEN; INTERLEUKIN 12; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CPG-OLIGONUCLEOTIDE; DEC-205 RECEPTOR; FASL PROTEIN, MOUSE; LECTIN; LEUKOCYTE ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; OLIGODEOXYRIBONUCLEOTIDE; SMALL INTERFERING RNA; TLR9 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DISEASE SEVERITY; INTESTINE FLORA; KUPFFER CELL; LIVER CELL; LIVER INJURY; LYMPHOCYTE ACTIVATION; MALE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYSTEMIC CIRCULATION; T CELL DEPLETION; TRANSGENIC MOUSE; VIRUS NEUTRALIZATION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; GENETICS; HEPATITIS B VIRUS; HUMAN; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; TOXIC HEPATITIS;

ANIMALS; ANTIGENS, CD; ANTIGENS, VIRAL; CELL COMMUNICATION; CHEMICAL AND DRUG INDUCED LIVER INJURY; CYTOTOXICITY, IMMUNOLOGIC; FAS LIGAND PROTEIN; FAS RECEPTOR; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; INTERLEUKIN-12; KUPFFER CELLS; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MINOR HISTOCOMPATIBILITY ANTIGENS; NATURAL KILLER T-CELLS; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, CELL SURFACE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9;

EID: 85026856013     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2015.111     Document Type: Article

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