Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation

Platelets

Volumn 23, Issue 3, 2012, Pages 195-201

  Lopes Pires, M Elisa ^a   Casarin, André L ^a   Pereira Cunha, Fernanda G ^a   Lorand Metze, Irene ^a   Antunes, Edson ^a   Marcondes, Sisi ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

lipopolysaccharide; N acetylcysteine; NADPH oxidase; Platelets; redox balance

Indexed keywords

ACETYLCYSTEINE; ADENOSINE DIPHOSPHATE; CATALASE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIPHENYLIODONIUM SALT; LIPOPOLYSACCHARIDE; MACROGOL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ARTICLE; CELL ASSAY; CONTROLLED STUDY; ESCHERICHIA COLI; EX VIVO STUDY; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE COUNT; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION;

ACETYLCYSTEINE; ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD PLATELETS; FREE RADICAL SCAVENGERS; LIPOPOLYSACCHARIDES; MALE; OXIDATION-REDUCTION; PLATELET AGGREGATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SEPSIS; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 84859770451     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2011.603065     Document Type: Article

References (35)

1. Victor VM, Rocha M, Esplugues JV, De la Fuente M. Role of free radicals in sepsis: Antioxidant therapy. Curr Pharm Des 2005;11:3141-3158.
2. Bhattacharyya J, Biswas S, Datta AG. Mode of action of endotoxin: Role of free radicals and antioxidants. Curr Med Chem 2004;11:359-368.
3. Kuckleburg CJ, Tiwari R, Czuprynski CJ. Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and-9 and generation of reactive oxygen species. Thromb Haemost 2008;99:363-372.
4. Keen RR, Stella L, Flanigan DP, Lands WE. Differential detection of plasma hydroperoxides in sepsis. Crit Care Med 1991;19:1114-1119.
5. Brandes RP, Schröder K. Differential vascular functions of Nox family NADPH oxidases. Curr Opin Lipidol 2008;19:513-518.
6. Bokoch GM, Diebold B, Kim JS, Gianni D. Emerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases. Antioxid Redox Signal 2009;11:2429-2441.
7. Sheu JR, Hung WC, Kan YC, Lee YM, Yen MH. Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human platelet. Br J Haematol 1998;103:29-38.
8. Morganti RP, Cardoso MHM, Pereira FG, Lorand-Metz I, De Nucci G, Marcondes S, Antunes E. Mechanisms underlying the inhibitory effects of lipopolysaccharide on human platelet adhesion. Platelets 2010;21:260-269.
9. Zielinski T, Wachowicz B, Saluk-Juszczak J, Kaca W. Polysaccharide part of Proteus mirabilis lipopolysaccharide may be responsible for the stimulation of platelet adhesion to collagen. Platelets 2002;13:419-424.
10. Saluk-Juszczak J, Wachowicz B, Zielinski T, Kaca W. Adhesion of thrombin-stimulated and unstimulated blood platelets to collagen in the presence of Proteus mirabilis lipopolysaccharides. Platelets 2001;12:470-475.
11. Zhang G, Han J, Welch EJ, Ye RD, Voyno-Yasenetskaya TA, Malik AB, Du X, Li Z. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/ MyD88 and the cGMP-dependent protein kinase pathway. J Immunol 2009;182:7997-8004.
12. Cicala C, Santacroce C, Itoh H, Douglas GJ, Page CP. A study on rat platelet responsiveness following intravenous endotoxin administration. Life Sci 1997;60:PL31-PL38.
13. Cerwinka WH, Cooper D, Krieglstein CF, Ross CR, McCord JM, Granger DN. Superoxide mediates endotoxininduced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol 2003;284:H535-H541.
14. Katayama T, Ikeda Y, Handa M, Tamatani T, Sakamoto S, Ito M, Ishimura Y, Suematsu M. Immunoneutralization of glycoprotein Ibalpha attenuates endotoxin-induced interactions of platelets and leukocytes with rat venular endothelium in vivo. Circ Res 2000;86:1031-1037.
15. V?́ctor VM, Rocha M, De la Fuente M. Regulation of macrophage function by the antioxidant N-acetylcysteine in mouse-oxidative stress by endotoxin. Int Immunopharmacol 2003;3:97-106.
16. Smith JA, Weidemann M. Further characterization of the neutrophil oxidative burst by flow cytometry. J Immunol Methods 1993;162:261-268.
17. Kitajima S, Tsuda M, Eshita N, Matsushima Y, Sayito M, Momma J, Kurokawa Y. Lipopolysaccharide-associated elevation of serum and urinary nitrite/nitrate levels and hematological changes in rats. Toxicol Lett 1995;78:135-140.
18. Pignatelli P, Sanguigni V, Lenti L, Ferro D, Finocchi A, Rossi P, Violi F. gp91phox-dependent expression of platelet CD40 ligand. Circulation 2004;110:1326-1329.
19. Seno T, Inoue N, Gao D, Okuda M, Sumi Y, Matsui K, Yamada S, Hirata KI, Kawashima S, Tawa R, et al. Involvement of NADH/NADPH oxidase in human platelet ROS production. Thromb Res 2001;103:399-409.
20. Tajima M, Sakagami H. Tetrahydrobiopterin impairs the action of endothelial nitric oxide via superoxide derived from platelets. Br J Pharmacol 2000;131:958-964.
21. Sheh YL, Hsu C, Chan SH, Chan JY. NADPH oxidase- and mitochondrion- derived superoxide at rostral ventrolateral medulla in endotoxin-induced cardiovascular depression. Free Radic Biol Med 2007;42:1610-1623.
22. DeLeo FR, Renee J, McCormick S, Nakamura M, Apicella M, Weiss JP, Nauseef WM. Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly. J Clin Invest 1998;101:455-463.
23. Li L, Frei B. Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: Inhibition by desferrioxamine. Arterioscler Thromb Vasc Biol 2009;29:732-738.
24. Kuwano Y, Tominaga K, Kawahara T, Sasaki H, Takeo K, Nishida K, Masuda K, Kawai T, Teshima-Kondo S, Rokutan K. Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic Biol Med 2008;45:1642-1652.
25. De Biase L, Pignatelli P, Lenti L, Tocci G, Piccioni F, Riondino S, Pulcinelli FM, Rubattu S, Volpe M, Violi F. Enhanced TNF alpha and oxidative stress in patients with heart failure: Effect of TNF alpha on platelet O2-production. Thromb Haemost 2003;90:317-325.
26. Kuwano Y, Kawahara T, Yamamoto H, Teshima-Kondo S, Tominaga K, Masuda K, Kishi K, Morita K, Rokutan K. Interferon-gamma activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells. Am J Physiol Cell Physiol 2006;290:C433-C443.
27. Owayed A, Dhaunsi GS, Al-Mukhaizeem F. Nitric oxidemediated activation of NADPH oxidase by salbutamol during acute asthma in children. Cell Biochem Funct 2008;26:603-608.
28. Begonja AJ, Gambaryan S, Geiger J, Aktas B, Pozgajova M, Nieswandt B, Walter U. Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. Blood 2005;106:2757-2760.
29. Salvemini D, de Nucci G, Sneddon JM, Vane JR. Superoxide anions enhance platelet adhesion and aggregation. Br J Pharmacol 1989;97:1145-1150.
30. Dong HP, Chen HW, Hsu C, Chiu HY, Lin LC, Yang RC. Previous heat shock treatment attenuates lipopolysaccharideinduced hyporesponsiveness of platelets in rats. Shock 2005;24:239-244.
31. Nassem KM, Chirico S, Mohammadi B, Bruckdorfer KR. The synergism of hydrogen peroxide with plasma S-nitrosothiols in the inhibition of platelet activation. Biochem J 1996;318:759-766.
32. Foresti R, Clark JE, Green CJ, Motterlini R. Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions. J Biol Chem 1997;272:18411-18417.
33. Myhre O, Andersen JM, Aarnes H, Fonnum F. Evaluation of the probes 20,70-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation. Biochem Pharmacol 2003;65:1575-1582.
34. Marcondes S, Cardoso MH, Morganti RP, Thomazzi SM, Lilla S, Murad F, De Nucci G, Antunes E. Cyclic GMPindependent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: A role for alphaactinin nitration. Proc Natl Acad Sci USA 2006; 103:3434-3439.
35. Cardoso MHM, Morganti RP, Lilla S, Murad F, De Nucci G, Antunes E, Marcondes S. The role of superoxide anion in the inhibitory effect of SIN-1 in thrombinactivated human platelet adhesion. Eur J Pharmacol 2011;627:229-234.