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Volumn 102, Issue 8, 2017, Pages 1324-1332

Patient-derived anti-β2GP1 antibodies recognize a peptide motif pattern and not a specific sequence of residues

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1; COMPLEMENTARY DNA; ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE II; HLA ANTIGEN CLASS 2; HYBRID PROTEIN; PEPTIDE FRAGMENT; PHOSPHOLIPID ANTIBODY; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR; AUTOANTIBODY; EPITOPE;

EID: 85026726700     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2017.170381     Document Type: Article
Times cited : (14)

References (36)
  • 1
    • 84874980560 scopus 로고    scopus 로고
    • The pathogenesis of the antiphospholipid syndrome
    • Giannakopoulos B, Krilis SA. The pathogenesis of the antiphospholipid syndrome. N Engl J Med. 2013;368(11):1033-1044.
    • (2013) N Engl J Med , vol.368 , Issue.11 , pp. 1033-1044
    • Giannakopoulos, B.1    Krilis, S.A.2
  • 2
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4(2):295-306.
    • (2006) J Thromb Haemost , vol.4 , Issue.2 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 3
    • 77956488547 scopus 로고    scopus 로고
    • Beta2-glycoprotein I can exist in 2 conformations: Implications for our understanding of the antiphospholipid syndrome
    • Agar C, van Os GM, Morgelin M, et al. Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood. 2010;116(8):1336-1343.
    • (2010) Blood , vol.116 , Issue.8 , pp. 1336-1343
    • Agar, C.1    Van Os, G.M.2    Morgelin, M.3
  • 4
    • 82455198748 scopus 로고    scopus 로고
    • Immune responses against domain I of beta(2)-glycoprotein I are driven by conformational changes: Domain I of beta(2)-glycoprotein I harbors a cryptic immunogenic epitope
    • de Laat B, van Berkel M, Urbanus RT, et al. Immune responses against domain I of beta(2)-glycoprotein I are driven by conformational changes: domain I of beta(2)-glycoprotein I harbors a cryptic immunogenic epitope. Arthritis Rheum. 2011; 63(12):3960-3968.
    • (2011) Arthritis Rheum , vol.63 , Issue.12 , pp. 3960-3968
    • De Laat, B.1    Van Berkel, M.2    Urbanus, R.T.3
  • 5
    • 33344456904 scopus 로고    scopus 로고
    • Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change
    • de Laat B, Derksen RH, van Lummel M, Pennings MT, de Groot PG. Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change. Blood. 2006; 107(5):1916-1924.
    • (2006) Blood , vol.107 , Issue.5 , pp. 1916-1924
    • De Laat, B.1    Derksen, R.H.2    Van Lummel, M.3    Pennings, M.T.4    De Groot, P.G.5
  • 6
    • 0037114142 scopus 로고    scopus 로고
    • Use of single point mutations in domain I of beta(2)-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies
    • Iverson GM, Reddel S, Victoria EJ, et al. Use of single point mutations in domain I of beta(2)-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies. J Immunol. 2002; 169(12):7097-7103.
    • (2002) J Immunol , vol.169 , Issue.12 , pp. 7097-7103
    • Iverson, G.M.1    Reddel, S.2    Victoria, E.J.3
  • 7
    • 33846236309 scopus 로고    scopus 로고
    • Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: Mutation studies including residues R39 to R43
    • Ioannou Y, Pericleous C, Giles I, et al. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum. 2007;56(1):280-290.
    • (2007) Arthritis Rheum , vol.56 , Issue.1 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3
  • 8
    • 84864386925 scopus 로고    scopus 로고
    • B-cell directed therapies in antiphospholipid antibody syndrome--new directions based on murine and human data
    • Khattri S, Zandman-Goddard G, Peeva E. B-cell directed therapies in antiphospholipid antibody syndrome--new directions based on murine and human data. Autoimmun Rev. 2012;11(10):717-722.
    • (2012) Autoimmun Rev , vol.11 , Issue.10 , pp. 717-722
    • Khattri, S.1    Zandman-Goddard, G.2    Peeva, E.3
  • 9
    • 84918547537 scopus 로고    scopus 로고
    • Antibodies to domain I of beta-2-glycopro-tein I and IgA antiphospholipid antibodies in patients with 'seronegative' antiphospholipid syndrome
    • Cousins L, Pericleous C, Khamashta M, et al. Antibodies to domain I of beta-2-glycopro-tein I and IgA antiphospholipid antibodies in patients with 'seronegative' antiphospholipid syndrome. Ann Rheum Dis. 2015;74(1):317-319.
    • (2015) Ann Rheum Dis , vol.74 , Issue.1 , pp. 317-319
    • Cousins, L.1    Pericleous, C.2    Khamashta, M.3
  • 10
    • 0034045920 scopus 로고    scopus 로고
    • T cells that are autoreactive to beta(2)-glycoprotein I in patients with antiphospholipid syndrome and healthy individuals
    • Hattori N, Kuwana M, Kaburaki J, et al. T cells that are autoreactive to beta(2)-glycoprotein I in patients with antiphospholipid syndrome and healthy individuals. Arthritis Rheum. 2000;43(1):65-75.
    • (2000) Arthritis Rheum , vol.43 , Issue.1 , pp. 65-75
    • Hattori, N.1    Kuwana, M.2    Kaburaki, J.3
  • 11
    • 0035885939 scopus 로고    scopus 로고
    • Autoreactive CD4(+) T-cell clones to beta2-glycoprotein I in patients with antiphospholipid syndrome: Preferential recognition of the major phospholipid-binding site
    • Arai T, Yoshida K, Kaburaki J, et al. Autoreactive CD4(+) T-cell clones to beta2-glycoprotein I in patients with antiphospholipid syndrome: preferential recognition of the major phospholipid-binding site. Blood. 2001;98(6):1889-1896.
    • (2001) Blood , vol.98 , Issue.6 , pp. 1889-1896
    • Arai, T.1    Yoshida, K.2    Kaburaki, J.3
  • 12
    • 0034066357 scopus 로고    scopus 로고
    • Analysis of T cell responses to the β2-glycoprotein I-derived peptide library in patients with anti-β2-glycoprotein I antibody-associ-ated autoimmunity
    • Ito H, Matsushita S, Tokano Y, et al. Analysis of T cell responses to the β2-glycoprotein I-derived peptide library in patients with anti-β2-glycoprotein I antibody-associ-ated autoimmunity. Hum Immunol. 2000;61(4):366-377.
    • (2000) Hum Immunol , vol.61 , Issue.4 , pp. 366-377
    • Ito, H.1    Matsushita, S.2    Tokano, Y.3
  • 13
    • 84885191223 scopus 로고    scopus 로고
    • Receptors involved in cell activation by antiphospholipid antibodies
    • Brandt KJ, Kruithof EKO, de Moerloose P. Receptors involved in cell activation by antiphospholipid antibodies. Thromb Res. 2013;132(4):408-413.
    • (2013) Thromb Res , vol.132 , Issue.4 , pp. 408-413
    • Brandt, K.J.1    Kruithof, E.K.O.2    De Moerloose, P.3
  • 14
    • 79551512120 scopus 로고    scopus 로고
    • Autoantibodies directed against domain I of beta2-glycoprotein I
    • de Laat B, de Groot PG. Autoantibodies directed against domain I of beta2-glycoprotein I. Curr Rheumatol Rep. 2011;13(1):70-76.
    • (2011) Curr Rheumatol Rep , vol.13 , Issue.1 , pp. 70-76
    • De Laat, B.1    De Groot, P.G.2
  • 16
    • 84928777989 scopus 로고    scopus 로고
    • β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome
    • Tanimura K, Jin H, Suenaga T, et al. β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome. Blood. 2015;125(18):2835-2844.
    • (2015) Blood , vol.125 , Issue.18 , pp. 2835-2844
    • Tanimura, K.1    Jin, H.2    Suenaga, T.3
  • 17
    • 0141638416 scopus 로고    scopus 로고
    • HLA class II alleles and genetic predisposition to the antiphospholipid syndrome
    • Domenico Sebastiani G, Minisola G, Galeazzi M. HLA class II alleles and genetic predisposition to the antiphospholipid syndrome. Autoimmun Rev. 2003;2(6):387-394.
    • (2003) Autoimmun Rev , vol.2 , Issue.6 , pp. 387-394
    • Domenico Sebastiani, G.1    Minisola, G.2    Galeazzi, M.3
  • 18
    • 2242465734 scopus 로고    scopus 로고
    • A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele
    • Anjos S, Nguyen A, Ounissi-Benkalha H, Tessier MC, Polychronakos C. A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele. J Biol Chem. 2002;277(48):46478-46486.
    • (2002) J Biol Chem , vol.277 , Issue.48 , pp. 46478-46486
    • Anjos, S.1    Nguyen, A.2    Ounissi-Benkalha, H.3    Tessier, M.C.4    Polychronakos, C.5
  • 19
    • 0023203468 scopus 로고
    • Generation of idiotypic and anti-idiotypic antibodies by immunization with peptides encoded by complementary RNA: A possible molecular basis for the network theory
    • Smith LR, Bost KL, Blalock JE. Generation of idiotypic and anti-idiotypic antibodies by immunization with peptides encoded by complementary RNA: a possible molecular basis for the network theory. J Immunol. 1987;138(1):7-9.
    • (1987) J Immunol , vol.138 , Issue.1 , pp. 7-9
    • Smith, L.R.1    Bost, K.L.2    Blalock, J.E.3
  • 20
    • 1842508029 scopus 로고    scopus 로고
    • Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3
    • Pendergraft WF, Preston GA, Shah RR, et al. Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3. Nat Med. 2004; 10(1):72-79.
    • (2004) Nat Med , vol.10 , Issue.1 , pp. 72-79
    • Pendergraft, W.F.1    Preston, G.A.2    Shah, R.R.3
  • 21
    • 85026745066 scopus 로고    scopus 로고
    • Significance of K(L/V)WX(I/L/V)P Epitope of the B2Gpi in Its (Patho)Physiologic Function
    • Žager U, Lunder M, Hodnik V, et al. Significance of K(L/V)WX(I/L/V)P Epitope of the B2Gpi in Its (Patho)Physiologic Function. EJIFCC. 2011;22(4):118-124.
    • (2011) EJIFCC , vol.22 , Issue.4 , pp. 118-124
    • Žager, U.1    Lunder, M.2    Hodnik, V.3
  • 22
    • 0036196287 scopus 로고    scopus 로고
    • Bacterial induction of autoantibodies to b2-glycopro-tein-1 accounts for the infectious etiology of antiphospholipid syndrome
    • Blank M, Krouse I, Fridkin M, et al. Bacterial induction of autoantibodies to b2-glycopro-tein-1 accounts for the infectious etiology of antiphospholipid syndrome. J Clin Invest. 2002;109:797-804.
    • (2002) J Clin Invest , vol.109 , pp. 797-804
    • Blank, M.1    Krouse, I.2    Fridkin, M.3
  • 23
    • 36049032373 scopus 로고    scopus 로고
    • Antiphospholipid syndrome associated with human herpesvirus-6 infection
    • Toyoshima M, Maegaki Y, Yotsumata K, Takei S, Kawano Y. Antiphospholipid syndrome associated with human herpesvirus-6 infection. Pediatr Neurol. 2007;37(6):449-451.
    • (2007) Pediatr Neurol , vol.37 , Issue.6 , pp. 449-451
    • Toyoshima, M.1    Maegaki, Y.2    Yotsumata, K.3    Takei, S.4    Kawano, Y.5
  • 25
    • 84993661555 scopus 로고    scopus 로고
    • Systematic review of case reports of antiphospholipid syndrome following infection
    • Abdel-Wahab N, Lopez-Olivo MA, Pinto-Patarroyo GP, Suarez-Almazor ME. Systematic review of case reports of antiphospholipid syndrome following infection. Lupus. 2016;25(14):1520-1531.
    • (2016) Lupus , vol.25 , Issue.14 , pp. 1520-1531
    • Abdel-Wahab, N.1    Lopez-Olivo, M.A.2    Pinto-Patarroyo, G.P.3    Suarez-Almazor, M.E.4
  • 26
    • 84886679576 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1
    • Durkin ML, Marchese D, Robinson MD, Ramgopal M. Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1. BMJ Case Rep. 2013;2013: bcr2013200474.
    • (2013) BMJ Case Rep , vol.2013
    • Durkin, M.L.1    Marchese, D.2    Robinson, M.D.3    Ramgopal, M.4
  • 27
    • 0025332717 scopus 로고
    • Antiphospholipid antibodies are directed against a complex antigen includes a lipid-binding inhibitor of coagulation: B2-glycoprotein I (apolipoprotein H)
    • McNeil HP, Simpson RJ, Chesterman CN, Krilis SA. Antiphospholipid antibodies are directed against a complex antigen includes a lipid-binding inhibitor of coagulation: B2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci USA. 1990;87:4120-4124.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4120-4124
    • McNeil, H.P.1    Simpson, R.J.2    Chesterman, C.N.3    Krilis, S.A.4
  • 28
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • Satta N, Dunoyer-Geindre S, Reber G, et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood. 2007; 109(4):1507-1514.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3
  • 29
    • 0141445991 scopus 로고    scopus 로고
    • Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2
    • Lutters BC, Derksen RH, Tekelenburg WL, et al. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'. J Biol Chem. 2003;278(36):33831-33838.
    • (2003) J Biol Chem , vol.278 , Issue.36 , pp. 33831-33838
    • Lutters, B.C.1    Derksen, R.H.2    Tekelenburg, W.L.3
  • 30
    • 77949262403 scopus 로고    scopus 로고
    • Human antiphospholipid antibodies induce TNFα in monocytes via Toll-like receptor 8
    • Döring Y, Hurst J, Lorenz M, et al. Human antiphospholipid antibodies induce TNFα in monocytes via Toll-like receptor 8. Immunobiology. 2010;215(3):230-241.
    • (2010) Immunobiology , vol.215 , Issue.3 , pp. 230-241
    • Döring, Y.1    Hurst, J.2    Lorenz, M.3
  • 31
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood. 2009;114:3074-3083.
    • (2009) Blood , vol.114 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 32
    • 84901193062 scopus 로고    scopus 로고
    • NF-kappaB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes
    • Brandt KJ, Fickentscher C, Boehlen F, Kruithof EK, de Moerloose P. NF-kappaB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes. J Thromb Haemost. 2014;12(5): 779-791.
    • (2014) J Thromb Haemost , vol.12 , Issue.5 , pp. 779-791
    • Brandt, K.J.1    Fickentscher, C.2    Boehlen, F.3    Kruithof, E.K.4    De Moerloose, P.5
  • 33
    • 34250721890 scopus 로고    scopus 로고
    • Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
    • Pierangeli SS, Vega-Ostertag ME, Raschi E, et al. Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann Rheum Dis. 2007;66(10):1327-1333.
    • (2007) Ann Rheum Dis , vol.66 , Issue.10 , pp. 1327-1333
    • Pierangeli, S.S.1    Vega-Ostertag, M.E.2    Raschi, E.3
  • 34
    • 67650067301 scopus 로고    scopus 로고
    • TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1β and caspase-1 in monocytes and dendritic cells
    • Hurst J, Prinz N, Lorenz M, et al. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1β and caspase-1 in monocytes and dendritic cells. Immunobiology. 2009;214(8):683-691.
    • (2009) Immunobiology , vol.214 , Issue.8 , pp. 683-691
    • Hurst, J.1    Prinz, N.2    Lorenz, M.3
  • 35
    • 84872747905 scopus 로고    scopus 로고
    • Involvement of TLR7 and TLR9 in the Production of Antiphospholipid Antibodies
    • Aguilar-Valenzuela R, Nickerson K, Romay-Penabad Z, et al. Involvement of TLR7 and TLR9 in the Production of Antiphospholipid Antibodies. Arthritis Rheum. 2011;63(10): S281-S282.
    • (2011) Arthritis Rheum , vol.63 , Issue.10 , pp. S281-S282
    • Aguilar-Valenzuela, R.1    Nickerson, K.2    Romay-Penabad, Z.3
  • 36
    • 33747023522 scopus 로고    scopus 로고
    • Anti-β2-glycoprotein I antibodies in complex with β2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V
    • Shi T, Giannakopoulos B, Yan X, et al. Anti-β2-glycoprotein I antibodies in complex with β2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum. 2006;54(8):2558-2567.
    • (2006) Arthritis Rheum , vol.54 , Issue.8 , pp. 2558-2567
    • Shi, T.1    Giannakopoulos, B.2    Yan, X.3


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