Tauroursodeoxycholic acid attenuates endoplasmic reticulum stress and protects the liver from chronic intermittent hypoxia induced injury

Experimental and Therapeutic Medicine

Volumn 14, Issue 3, 2017, Pages 2461-2468

  Hou, Yanpeng ^a,b   Yang, Huai’an ^a   Cui, Zeshi ^a   Tai, Xuhui ^b   Chu, Yanling ^b   Guo, Xing ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b The 463rd Hospital of The Chinese People s Liberation Army   (China)

Author keywords

Apoptosis; Chronic intermittent hypoxia; Endoplasmic reticulum stress; Liver; Obstructive sleep apnea; Tauroursodeoxycholic acid

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 12; CASPASE 3; CASPASE 9; CHAPERONE; CHAPERONE 78; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; INTERLEUKIN 1BETA; PROTEIN IRE1; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TAUROURSODEOXYCHOLIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMICAL ANALYSIS; CHRONIC INTERMITTENT HYPOXIA; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HEPATOCYTE APOPTOSIS; HISTOLOGY; HYPOXIA; INFLAMMATION; LIVER FUNCTION; LIVER INJURY; LIVER ISCHEMIA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; SLEEP DISORDERED BREATHING; TUNEL ASSAY; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

EID: 85026672158     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2017.4804     Document Type: Article

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