Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Oncotarget

Volumn 6, Issue 29, 2015, Pages 28011-28025

  Vandewyncke, Yves Paul ^a   Laukens, Debby ^a   Devisscher, Lindsey ^a   Paridaens, Annelies ^a   Bogaerts, Eliene ^a   Verhelst, Xavier ^a   Van den Bussche, Anja ^a   Raevens, Sarah ^a   Van Govaere, Christophe ^a   Van Troys, Marleen ^a   Ampe, Christophe ^a   Descamps, Benedicte ^a   Vanhove, Chris ^a   Govaere, Olivier ^b   Geerts, Anja ^a   Van Vlierberghe, Hans ^a  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF IMAGING AND PATHOLOGY   (Belgium)

Author keywords

Chaperone; Chemo prevention; Hepatocellular carcinoma; Inflammation; Unfolded protein response

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARCINOGEN; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN; DIETHYLNITROSAMINE; I KAPPA B ALPHA; INITIATION FACTOR 2ALPHA; TAUROURSODEOXYCHOLIC ACID; ANTINEOPLASTIC AGENT; TAUROCHENODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL INVASION; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MEGADOSE; ENDOPLASMIC RETICULUM STRESS; HEPATITIS; HEPATOCELLULAR CARCINOMA CELL LINE; IN VITRO STUDY; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; UNFOLDED PROTEIN RESPONSE; ANIMAL; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; HEP-G2 CELL LINE; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER TUMOR; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUNEL ASSAY; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, HEPATOCELLULAR; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; HEP G2 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LIVER NEOPLASMS; MALE; MICE; REAL-TIME POLYMERASE CHAIN REACTION; TAUROCHENODEOXYCHOLIC ACID; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84944474626     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4377     Document Type: Article

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