Roles of ramR and tet(A) mutations in conferring tigecycline resistance in carbapenem-resistant Klebsiella pneumoniae clinical isolates

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 8, 2017, Pages

  Chiu, Sheng Kang ^a,b   Huang, Li Yueh ^c   Chen, Hsi ^b   Tsai, Yu Kuo ^c   Liou, Ci Hong ^c   Lin, Jung Chung ^a   Siu, L Kristopher ^a,c,d   Chang, Feng Yee ^a   Yeh, Kuo Ming ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Klebsiella pneumoniae; ramR; tet(A); Tigecycline resistance

Indexed keywords

TIGECYCLINE; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE; CARRIER PROTEIN; MINOCYCLINE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN; TRANSACTIVATOR PROTEIN;

AMPLICON; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE; FRAMESHIFT MUTATION; GENE EXPRESSION; GENE MUTATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RAMR GENE; SEQUENCE ANALYSIS; TETA GENE; ANALOGS AND DERIVATIVES; CARBAPENEM-RESISTANT ENTEROBACTERIACEAE; DRUG EFFECT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MICROBIAL SENSITIVITY TEST; MUTATION; TETRACYCLINE RESISTANCE;

ANTI-BACTERIAL AGENTS; CARBAPENEM-RESISTANT ENTEROBACTERIACEAE; CARBAPENEMS; DRUG RESISTANCE, BACTERIAL; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PLASMIDS; TETRACYCLINE RESISTANCE; TRANS-ACTIVATORS;

EID: 85026376056     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00391-17     Document Type: Article

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