-
1
-
-
84939240528
-
Allele, phenotype and disease data at Mouse Genome Informatics: Improving access and analysis
-
Bello, S.M., Smith, C.L. &Eppig, J.T. Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis. Mamm. Genome 26, 285-294 (2015).
-
(2015)
Mamm. Genome
, vol.26
, pp. 285-294
-
-
Bello, S.M.1
Smith, C.L.2
Eppig, J.T.3
-
2
-
-
84859169880
-
Drug development: Raise standards for preclinical cancer research
-
Begley, C.G. &Ellis, L.M. Drug development: raise standards for preclinical cancer research. Nature 483, 531-533 (2012).
-
(2012)
Nature
, vol.483
, pp. 531-533
-
-
Begley, C.G.1
Ellis, L.M.2
-
3
-
-
84870768385
-
Measuring behavior of animal models: Faults and remedies
-
Fonio, E., Golani, I. &Benjamini, Y. Measuring behavior of animal models: faults and remedies. Nat. Methods 9, 1167-1170 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 1167-1170
-
-
Fonio, E.1
Golani, I.2
Benjamini, Y.3
-
4
-
-
85041813459
-
Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research
-
Kilkenny, C., Browne, W.J., Cuthill, I.C., Emerson, M. &Altman, D.G. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol. 8, e1000412 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000412
-
-
Kilkenny, C.1
Browne, W.J.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
5
-
-
84867337003
-
The International Mouse Phenotyping Consortium: Past and future perspectives on mouse phenotyping
-
Brown, S.D.M. &Moore, M.W. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Mamm. Genome 23, 632-640 (2012).
-
(2012)
Mamm. Genome
, vol.23
, pp. 632-640
-
-
Brown, S.D.M.1
Moore, M.W.2
-
6
-
-
84940571939
-
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
-
Hraběde Angelis, M. et al. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nat. Genet. 47, 969-978 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 969-978
-
-
Hraběde, A.M.1
-
7
-
-
79959210305
-
A conditional knockout resource for the genome-wide study of mouse gene function
-
Skarnes, W.C. et al. A conditional knockout resource for the genome-wide study of mouse gene function. Nature 474, 337-342 (2011).
-
(2011)
Nature
, vol.474
, pp. 337-342
-
-
Skarnes, W.C.1
-
8
-
-
84867332476
-
The mammalian gene function resource: The International Knockout Mouse Consortium
-
Bradley, A. et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm. Genome 23, 580-586 (2012).
-
(2012)
Mamm. Genome
, vol.23
, pp. 580-586
-
-
Bradley, A.1
-
9
-
-
84943818659
-
Beyond knockouts: The International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes
-
Rosen, B., Schick, J. &Wurst, W. Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes. Mamm. Genome 26, 456-466 (2015).
-
(2015)
Mamm. Genome
, vol.26
, pp. 456-466
-
-
Rosen, B.1
Schick, J.2
Wurst, W.3
-
10
-
-
84989204804
-
High-throughput discovery of novel developmental phenotypes
-
Dickinson, M.E. et al. High-throughput discovery of novel developmental phenotypes. Nature 537, 508-514 (2016).
-
(2016)
Nature
, vol.537
, pp. 508-514
-
-
Dickinson, M.E.1
-
11
-
-
84877821168
-
Bloomsbury report on mouse embryo phenotyping: Recommendations from the IMPC workshop on embryonic lethal screening
-
Adams, D. et al. Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Dis. Model. Mech. 6, 571-579 (2013).
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 571-579
-
-
Adams, D.1
-
12
-
-
84940062348
-
PhenStat: A tool kit for standardized analysis of high throughput phenotypic data
-
Kurbatova, N., Mason, J.C., Morgan, H., Meehan, T.F. &Karp, N.A. PhenStat: a tool kit for standardized analysis of high throughput phenotypic data. PLoS One 10, e0131274 (2015).
-
(2015)
PLoS One
, vol.10
, pp. e0131274
-
-
Kurbatova, N.1
Mason, J.C.2
Morgan, H.3
Meehan, T.F.4
Karp, N.A.5
-
13
-
-
84927740488
-
A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines
-
West, D.B. et al. A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines. Genome Res. 25, 598-607 (2015).
-
(2015)
Genome Res.
, vol.25
, pp. 598-607
-
-
West, D.B.1
-
14
-
-
84900406282
-
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen
-
Adissu, H.A. et al. Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis. Model. Mech. 7, 515-524 (2014).
-
(2014)
Dis. Model. Mech.
, vol.7
, pp. 515-524
-
-
Adissu, H.A.1
-
15
-
-
84891757565
-
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
-
Koscielny, G. et al. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 42, D802-D809 (2014).
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D802-D809
-
-
Koscielny, G.1
-
16
-
-
84934323188
-
The economics of reproducibility in preclinical research
-
Freedman, L.P., Cockburn, I.M. &Simcoe, T.S. The economics of reproducibility in preclinical research. PLoS Biol. 13, e1002165 (2015).
-
(2015)
PLoS Biol.
, vol.13
, pp. e1002165
-
-
Freedman, L.P.1
Cockburn, I.M.2
Simcoe, T.S.3
-
17
-
-
84946081339
-
OMIM.org: Online Mendelian Inheritance in Man (OMIM® ), an online catalog of human genes and genetic disorders
-
Amberger, J.S., Bocchini, C.A., Schiettecatte, F., Scott, A.F. &Hamosh, A. OMIM.org: Online Mendelian Inheritance in Man (OMIM® ), an online catalog of human genes and genetic disorders. Nucleic Acids Res. 43, D789-D798 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D789-D798
-
-
Amberger, J.S.1
Bocchini, C.A.2
Schiettecatte, F.3
Scott, A.F.4
Hamosh, A.5
-
18
-
-
84864358886
-
Representation of rare diseases in health information systems: The Orphanet approach to serve a wide range of end users
-
Rath, A. et al. Representation of rare diseases in health information systems: the Orphanet approach to serve a wide range of end users. Hum. Mutat. 33, 803-808 (2012).
-
(2012)
Hum. Mutat.
, vol.33
, pp. 803-808
-
-
Rath, A.1
-
19
-
-
85015982066
-
The Human Phenotype Ontology in 2017
-
Köhler, S. et al. The Human Phenotype Ontology in 2017. Nucleic Acids Res. 45, D1, D865-D876 (2017).
-
(2017)
Nucleic Acids Res.
, vol.45
, Issue.D1
, pp. D865-D876
-
-
Köhler, S.1
-
20
-
-
84941880519
-
Use of model organism and disease databases to support matchmaking for human disease gene discovery
-
Mungall, C.J. et al. Use of model organism and disease databases to support matchmaking for human disease gene discovery. Hum. Mutat. 36, 979-984 (2015).
-
(2015)
Hum. Mutat.
, vol.36
, pp. 979-984
-
-
Mungall, C.J.1
-
21
-
-
84938782540
-
Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens
-
Smith, C.L. &Eppig, J.T. Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens. J. Biomed. Semantics 6, 11 (2015).
-
(2015)
J. Biomed. Semantics
, vol.6
, pp. 11
-
-
Smith, C.L.1
Eppig, J.T.2
-
22
-
-
84885393730
-
PhenoDigm: Analyzing curated annotations to associate animal models with human diseases
-
Smedley, D. et al. PhenoDigm: analyzing curated annotations to associate animal models with human diseases. Database (Oxford) 2013, bat025 (2013).
-
(2013)
Database (Oxford)
, vol.2013
, pp. bat025
-
-
Smedley, D.1
-
23
-
-
84906056536
-
Spectrum of the mutations in Bernard-Soulier syndrome
-
Savoia, A. et al. Spectrum of the mutations in Bernard-Soulier syndrome. Hum. Mutat. 35, 1033-1045 (2014).
-
(2014)
Hum. Mutat.
, vol.35
, pp. 1033-1045
-
-
Savoia, A.1
-
24
-
-
85027927057
-
Genetics of human Bardet-Biedl syndrome, an updates
-
Khan, S.A. et al. Genetics of human Bardet-Biedl syndrome, an updates. Clin. Genet. 90, 3-15 (2016).
-
(2016)
Clin. Genet.
, vol.90
, pp. 3-15
-
-
Khan, S.A.1
-
25
-
-
84877935385
-
Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination
-
Margolin, D.H. et al. Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination. N. Engl. J. Med. 368, 1992-2003 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1992-2003
-
-
Margolin, D.H.1
-
26
-
-
84929118585
-
RNF216 mutations as a novel cause of autosomal recessive Huntington-like disorder
-
Santens, P. et al. RNF216 mutations as a novel cause of autosomal recessive Huntington-like disorder. Neurology 84, 1760-1766 (2015).
-
(2015)
Neurology
, vol.84
, pp. 1760-1766
-
-
Santens, P.1
-
27
-
-
84880562927
-
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
-
White, J.K. et al. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell 154, 452-464 (2013).
-
(2013)
Cell
, vol.154
, pp. 452-464
-
-
White, J.K.1
-
28
-
-
84946735654
-
Gene Ontology Consortium: Going forward
-
Gene Ontology Consortium
-
Gene Ontology Consortium. Gene Ontology Consortium: going forward. Nucleic Acids Res. 43, D1049-D1056 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D1049-D1056
-
-
-
29
-
-
84895734902
-
Functionally enigmatic genes: A case study of the brain ignorome
-
Pandey, A.K., Lu, L., Wang, X., Homayouni, R. &Williams, R.W. Functionally enigmatic genes: a case study of the brain ignorome. PLoS One 9, e88889 (2014).
-
(2014)
PLoS One
, vol.9
, pp. e88889
-
-
Pandey, A.K.1
Lu, L.2
Wang, X.3
Homayouni, R.4
Williams, R.W.5
-
30
-
-
84976878197
-
Expression Atlas update: An integrated database of gene and protein expression in humans, animals and plants
-
Petryszak, R. et al. Expression Atlas update: an integrated database of gene and protein expression in humans, animals and plants. Nucleic Acids Res. 44, D746-D752 (2016).
-
(2016)
Nucleic Acids Res.
, vol.44
, pp. D746-D752
-
-
Petryszak, R.1
-
31
-
-
84873590369
-
Ontogeny of erythroid gene expression
-
Kingsley, P.D. et al. Ontogeny of erythroid gene expression. Blood 121, e5-e13 (2013).
-
(2013)
Blood
, vol.121
, pp. e5-e13
-
-
Kingsley, P.D.1
-
32
-
-
78649549671
-
The ribosomal basis of Diamond-Blackfan anemia: Mutation and database update
-
Boria, I. et al. The ribosomal basis of Diamond-Blackfan anemia: mutation and database update. Hum. Mutat. 31, 1269-1279 (2010).
-
(2010)
Hum. Mutat.
, vol.31
, pp. 1269-1279
-
-
Boria, I.1
-
33
-
-
84906860649
-
Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization
-
Kizil, C. et al. Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development 141, 3529-3539 (2014).
-
(2014)
Development
, vol.141
, pp. 3529-3539
-
-
Kizil, C.1
-
34
-
-
84947907035
-
Next-generation diagnostics and disease-gene discovery with the Exomiser
-
Smedley, D. et al. Next-generation diagnostics and disease-gene discovery with the Exomiser. Nat. Protoc. 10, 2004-2015 (2015).
-
(2015)
Nat. Protoc.
, vol.10
, pp. 2004-2015
-
-
Smedley, D.1
-
35
-
-
84975063087
-
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency
-
Bone, W.P. et al. Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency. Genet. Med. 18, 608-617 (2016).
-
(2016)
Genet. Med.
, vol.18
, pp. 608-617
-
-
Bone, W.P.1
-
36
-
-
84937162820
-
Trace amine-associated receptor 1 regulation of methamphetamine intake and related traits
-
Harkness, J.H., Shi, X., Janowsky, A. &Phillips, T.J. Trace amine-associated receptor 1 regulation of methamphetamine intake and related traits. Neuropsychopharmacology 40, 2175-2184 (2015).
-
(2015)
Neuropsychopharmacology
, vol.40
, pp. 2175-2184
-
-
Harkness, J.H.1
Shi, X.2
Janowsky, A.3
Phillips, T.J.4
-
37
-
-
84989281322
-
Genetic associations with obstructive sleep apnea traits in Hispanic/Latino Americans
-
Cade, B.E. et al. Genetic associations with obstructive sleep apnea traits in Hispanic/Latino Americans. Am. J. Respir. Crit. Care Med. 194, 886-897 (2016).
-
(2016)
Am. J. Respir. Crit. Care Med.
, vol.194
, pp. 886-897
-
-
Cade, B.E.1
-
38
-
-
84956618075
-
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene
-
Knowles, J.W. et al. Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. J. Clin. Invest. 126, 403 (2016).
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 403
-
-
Knowles, J.W.1
-
39
-
-
84894107556
-
Recurrent deletions of ULK4 in schizophrenia: A gene crucial for neuritogenesis and neuronal motility
-
Lang, B. et al. Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility. J. Cell Sci. 127, 630-640 (2014).
-
(2014)
J. Cell Sci.
, vol.127
, pp. 630-640
-
-
Lang, B.1
-
40
-
-
84983593713
-
A genome-wide association study for regulators of micronucleus formation in mice
-
McIntyre, R.E. et al. A genome-wide association study for regulators of micronucleus formation in mice. G3 (Bethesda) 6, 2343-2354 (2016).
-
(2016)
G3 (Bethesda)
, vol.6
, pp. 2343-2354
-
-
McIntyre, R.E.1
-
41
-
-
84960127874
-
Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture
-
Levy, R., Mott, R.F., Iraqi, F.A. &Gabet, Y. Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture. BMC Genomics 16, 1013 (2015).
-
(2015)
BMC Genomics
, vol.16
, pp. 1013
-
-
Levy, R.1
Mott, R.F.2
Iraqi, F.A.3
Gabet, Y.4
-
42
-
-
78651284860
-
The IKMC web portal: A central point of entry to data and resources from the International Knockout Mouse Consortium
-
Ringwald, M. et al. The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res. 39, D849-D855 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. D849-D855
-
-
Ringwald, M.1
-
43
-
-
84871552302
-
Robust and sensitive analysis of mouse knockout phenotypes
-
Karp, N.A., Melvin, D., Sanger Mouse Genetics Project &Mott, R.F. Robust and sensitive analysis of mouse knockout phenotypes. PLoS One 7, e52410 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e52410
-
-
Karp, N.A.1
Melvin, D.2
Mott, R.F.3
-
44
-
-
84857745267
-
Database resources of the National Center for Biotechnology Information
-
Sayers, E.W. et al. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 40, D13-D25 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D13-D25
-
-
Sayers, E.W.1
-
45
-
-
70449356774
-
QuickGO: A web-based tool for Gene Ontology searching
-
Binns, D. et al. QuickGO: a web-based tool for Gene Ontology searching. Bioinformatics 25, 3045-3046 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 3045-3046
-
-
Binns, D.1
|