Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 30, 2017, Pages E6260-E6269

  Liszt, Kathrin Ingrid ^a,b   Ley, Jakob Peter ^c   Lieder, Barbara ^a,b   Behrens, Maik ^d   Stöger, Verena ^b   Reiner, Angelika ^e   Hochkogler, Christina Maria ^b   Köck, Elke ^a   Marchiori, Alessandro ^d   Hans, Joachim ^c   Widder, Sabine ^c   Krammer, Gerhard ^c   Sanger, Gareth John ^f   Somoza, Mark Manuel ^a   Meyerhof, Wolfgang ^d   Somoza, Veronika ^a,b  

^a UNIVERSITY OF VIENNA   (Austria)

^b INSTITUTE FOR MICROELECTRONICS   (Austria)

^c SYMRISE AG   (Germany)

^d GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^e Wiener Krankenanstaltenverbund   (Austria)

^f Blizzard Institute   (Germany)

Author keywords

Bitter taste receptors; Caffeine; Gastric acid secretion; Homoeriodictyol; TAS2Rs

Indexed keywords

ADENYLATE CYCLASE; CAFFEINE; CALCIUM ION; CYCLIC AMP; ERIODICTYOL; MESSENGER RNA; RECEPTOR PROTEIN; TAS2R43 PROTEIN; TASTE TYPE 2 BITTER RECEPTOR; UNCLASSIFIED DRUG; FLAVONE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; HOMOERIODICTYOL;

ARTICLE; BITTER TASTE; CALCIUM MOBILIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MOUTH CAVITY; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOMACH ACID SECRETION; STOMACH PARIETAL CELL; STOMACH PH; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); STOMACH ACID; TASTE;

CAFFEINE; FLAVONES; GASTRIC ACID; HUMANS; PARIETAL CELLS, GASTRIC; RECEPTORS, G-PROTEIN-COUPLED; TASTE;

EID: 85025837750     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1703728114     Document Type: Article

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