Modulation of polypeptide conformation through donor-acceptor transformation of side-chain hydrogen bonding ligands

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Song, Ziyuan ^a   Mansbach, Rachael A ^a   He, Hua ^b   Shih, Kuo Chih ^c,d   Baumgartner, Ryan ^e   Zheng, Nan ^a   Ba, Xiaochu ^e   Huang, Yinzhao ^e   Mani, Deepak ^a   Liu, Yun ^f,g   Lin, Yao ^c   Nieh, Mu Ping ^c   Ferguson, Andrew L ^a,e   Yin, Lichen ^b   Cheng, Jianjun ^a  

^a University of Illinois at Urbana Champaign   (United States)

^b SOOCHOW UNIVERSITY   (China)

^c UNIVERSITY OF CONNECTICUT   (United States)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^g UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; AMIDE; ESTER; LIGAND; POLYPEPTIDE; SIDE CHAIN H BONDING LIGAND; UNCLASSIFIED DRUG; BIOPOLYMER; PEPTIDE; TRIAZOLE DERIVATIVE;

CELLS AND CELL COMPONENTS; CHEMICAL BONDING; EXPERIMENTAL STUDY; HYDROGEN; LIGAND; PEPTIDE; POLYMER; TRANSFORMATION;

ALPHA HELIX; ANIMAL CELL; ARTICLE; ENDOLYSOSOME; HUMAN; HUMAN CELL; LYSOSOME; MEMBRANE PERMEABILITY; NONHUMAN; PH; PROTEIN CONFORMATION; PROTON TRANSPORT; ANIMAL; CONFOCAL MICROSCOPY; HELA CELL LINE; HYDROGEN BOND; METABOLISM; MOLECULAR MODEL; MOUSE; NIH 3T3 CELL LINE; PROTEIN SECONDARY STRUCTURE; SPECTROSCOPY;

ANIMALS; BIOPOLYMERS; HELA CELLS; HUMANS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; LIGANDS; MICE; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; NIH 3T3 CELLS; PEPTIDES; PROTEIN CONFORMATION; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN STRUCTURE, SECONDARY; SPECTRUM ANALYSIS; TRIAZOLES;

EID: 85025480640     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00079-5     Document Type: Article

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