-
1
-
-
84951567833
-
Tau in physiology and pathology
-
Wang, Y., Mandelkow, E., Tau in physiology and pathology. Nat Neurosci 17 (2016), 5–21.
-
(2016)
Nat Neurosci
, vol.17
, pp. 5-21
-
-
Wang, Y.1
Mandelkow, E.2
-
2
-
-
84995451096
-
Therapeutic strategies for the treatment of tauopathies: Hopes and challenges
-
Khanna, M.R., Kovalevich, J., Lee, V.M., Trojanowski, J.Q., Brunden, K.R., Therapeutic strategies for the treatment of tauopathies: Hopes and challenges. Alzheimers Dement 12 (2016), 1051–1065.
-
(2016)
Alzheimers Dement
, vol.12
, pp. 1051-1065
-
-
Khanna, M.R.1
Kovalevich, J.2
Lee, V.M.3
Trojanowski, J.Q.4
Brunden, K.R.5
-
3
-
-
84873640196
-
Dopamine D2 Receptor antagonism suppresses tau aggregation and neurotoxicity
-
McCormick, A.V., Wheeler, J.M., Guthrie, C.R., Liachko, N.F., Kraemer, B.C., Dopamine D2 Receptor antagonism suppresses tau aggregation and neurotoxicity. Biol Psychiatry 73 (2013), 464–471.
-
(2013)
Biol Psychiatry
, vol.73
, pp. 464-471
-
-
McCormick, A.V.1
Wheeler, J.M.2
Guthrie, C.R.3
Liachko, N.F.4
Kraemer, B.C.5
-
4
-
-
0042889049
-
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
-
Kraemer, B.C., Zhang, B., Leverenz, J.B., Thomas, J.H., Trojanowski, J.Q., Schellenberg, G.D., Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy. Proc Natl Acad Sci U S A 100 (2003), 9980–9985.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9980-9985
-
-
Kraemer, B.C.1
Zhang, B.2
Leverenz, J.B.3
Thomas, J.H.4
Trojanowski, J.Q.5
Schellenberg, G.D.6
-
5
-
-
84864381531
-
Loss of dopaminoreceptive neuron causes L-dopa resistant parkinsonism in tauopathy
-
Chiba, S., Takada, E., Tadokoro, M., Taniguchi, T., Kadoyama, K., Takenokuchi, M., et al. Loss of dopaminoreceptive neuron causes L-dopa resistant parkinsonism in tauopathy. Neurobiol Aging 33 (2012), 2491–2505.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2491-2505
-
-
Chiba, S.1
Takada, E.2
Tadokoro, M.3
Taniguchi, T.4
Kadoyama, K.5
Takenokuchi, M.6
-
6
-
-
84886684036
-
Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau
-
Wu, T.H., Lu, Y.N., Chuang, C.L., Wu, C.L., Chiang, A.S., Krantz, D.E., et al. Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol 125 (2013), 711–725.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 711-725
-
-
Wu, T.H.1
Lu, Y.N.2
Chuang, C.L.3
Wu, C.L.4
Chiang, A.S.5
Krantz, D.E.6
-
7
-
-
68949175463
-
Dopamine D1 receptor activation induces tau phosphorylation via cdk5 and GSK3 signaling pathways
-
Lebel, M., Patenaude, C., Allyson, J., Massicotte, G., Cyr, M., Dopamine D1 receptor activation induces tau phosphorylation via cdk5 and GSK3 signaling pathways. Neuropharmacology 57 (2009), 392–402.
-
(2009)
Neuropharmacology
, vol.57
, pp. 392-402
-
-
Lebel, M.1
Patenaude, C.2
Allyson, J.3
Massicotte, G.4
Cyr, M.5
-
8
-
-
84978492590
-
Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer's disease
-
Koppel, J., Jimenez, H., Adrien, L., Greenwald, B.S., Marambaud, P., Cinamon, E., et al. Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer's disease. Alzheimers Dement Transl Res Clin Interv 2 (2016), 121–130.
-
(2016)
Alzheimers Dement Transl Res Clin Interv
, vol.2
, pp. 121-130
-
-
Koppel, J.1
Jimenez, H.2
Adrien, L.3
Greenwald, B.S.4
Marambaud, P.5
Cinamon, E.6
-
9
-
-
85015205245
-
Classics in chemical neuroscience: Haloperidol
-
Tyler, M.W., Zaldivar-Diez, J., Haggarty, S.J., Classics in chemical neuroscience: Haloperidol. ACS Chem Neurosci 8 (2017), 444–453.
-
(2017)
ACS Chem Neurosci
, vol.8
, pp. 444-453
-
-
Tyler, M.W.1
Zaldivar-Diez, J.2
Haggarty, S.J.3
-
10
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner, S., The genetics of Caenorhabditis elegans. Genetics 77 (1974), 71–94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
11
-
-
78649750391
-
Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy
-
Liachko, N.F., Guthrie, C.R., Kramer, B.C., Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy. J Neurosci 30 (2010), 16208–16219.
-
(2010)
J Neurosci
, vol.30
, pp. 16208-16219
-
-
Liachko, N.F.1
Guthrie, C.R.2
Kramer, B.C.3
-
12
-
-
84919674247
-
Dopamine receptors – IUPHAR review 13
-
Beaulieu, J.M., Espinoza, S., Gainetdinov, R.R., Dopamine receptors – IUPHAR review 13. Br J Pharmacol 172 (2015), 1–23.
-
(2015)
Br J Pharmacol
, vol.172
, pp. 1-23
-
-
Beaulieu, J.M.1
Espinoza, S.2
Gainetdinov, R.R.3
-
13
-
-
5444225556
-
Function and evolution of the serotonin-synthetic bas-1 gene and other aromatic amino acid decarboxylase genes in Caenorhabditis
-
Hare, E.E., Loer, C.M., Function and evolution of the serotonin-synthetic bas-1 gene and other aromatic amino acid decarboxylase genes in Caenorhabditis. BMC Evol Biol, 4, 2004, 24.
-
(2004)
BMC Evol Biol
, vol.4
, pp. 24
-
-
Hare, E.E.1
Loer, C.M.2
-
14
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
Schneider, A., Biernat, J., von Bergen, M., Mandelkow, E., Mandelkow, E.M., Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. Biochemistry 38 (1999), 3548–3558.
-
(1999)
Biochemistry
, vol.38
, pp. 3548-3558
-
-
Schneider, A.1
Biernat, J.2
von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
15
-
-
84868154722
-
Sensitive quantitative assays for tau and phosphor-tau in transgenic mouse models
-
Acker, C.M., Forest, S.K., Zinkowski, R., Davies, P., d'Abramo, C., Sensitive quantitative assays for tau and phosphor-tau in transgenic mouse models. Neurobiol Aging 34 (2013), 338–350.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 338-350
-
-
Acker, C.M.1
Forest, S.K.2
Zinkowski, R.3
Davies, P.4
d'Abramo, C.5
-
16
-
-
61349097283
-
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases
-
Yu, Y., Run, X., Liang, Z., Li, Y., Liu, F., Liu, Y., et al. Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases. J Neurochem 108 (2009), 1480–1494.
-
(2009)
J Neurochem
, vol.108
, pp. 1480-1494
-
-
Yu, Y.1
Run, X.2
Liang, Z.3
Li, Y.4
Liu, F.5
Liu, Y.6
-
17
-
-
0033179477
-
Coordinated transcriptional regulation of the unc-25 glutamic acid decarboxylase and the unc-47 GABA vesicular transporter by the Caenorhabditis elegans UNC-30 homeodomain protein
-
Eastman, C., Horvitz, H.R., Jin, Y., Coordinated transcriptional regulation of the unc-25 glutamic acid decarboxylase and the unc-47 GABA vesicular transporter by the Caenorhabditis elegans UNC-30 homeodomain protein. J Neurosci 19 (1999), 6224–6234.
-
(1999)
J Neurosci
, vol.19
, pp. 6224-6234
-
-
Eastman, C.1
Horvitz, H.R.2
Jin, Y.3
-
18
-
-
84896779639
-
Longevity manipulations differentially affect serotonin/dopamine level and behavioral deterioration in aging Caenorhabditis elegans
-
Yin, J.A., Liu, X.J., Yuan, J., Jiang, J., Cai, S.Q., Longevity manipulations differentially affect serotonin/dopamine level and behavioral deterioration in aging Caenorhabditis elegans. J Neurosci 34 (2014), 3947–3958.
-
(2014)
J Neurosci
, vol.34
, pp. 3947-3958
-
-
Yin, J.A.1
Liu, X.J.2
Yuan, J.3
Jiang, J.4
Cai, S.Q.5
-
19
-
-
0033714116
-
C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
-
Sawin, E.R., Ranganathan, R., Horvitz, H.R., C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 26 (2000), 619–631.
-
(2000)
Neuron
, vol.26
, pp. 619-631
-
-
Sawin, E.R.1
Ranganathan, R.2
Horvitz, H.R.3
-
20
-
-
0342680006
-
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
-
Sze, J.W., Victor, M., Loer, C., Shi, Y., Ruvkun, G., Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 403 (2000), 560–564.
-
(2000)
Nature
, vol.403
, pp. 560-564
-
-
Sze, J.W.1
Victor, M.2
Loer, C.3
Shi, Y.4
Ruvkun, G.5
-
21
-
-
0016766336
-
Dopaminergic neurons in the nematode Caenorhabditis elegans
-
Sulston, J., Dew, M., Brenner, S., Dopaminergic neurons in the nematode Caenorhabditis elegans. J Comp Neurol 163 (1975), 215–226.
-
(1975)
J Comp Neurol
, vol.163
, pp. 215-226
-
-
Sulston, J.1
Dew, M.2
Brenner, S.3
-
22
-
-
0027131206
-
Serotonin-deficient mutants and male mating behavior in the nematode Caenorhabditis elegans
-
Loer, C.M., Kenyon, C.J., Serotonin-deficient mutants and male mating behavior in the nematode Caenorhabditis elegans. J Neurosci 13 (1993), 5407–5417.
-
(1993)
J Neurosci
, vol.13
, pp. 5407-5417
-
-
Loer, C.M.1
Kenyon, C.J.2
-
23
-
-
84928998060
-
Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4)
-
Loer, C.M., Calvo, A.C., Watschinger, K., Werner-Felmayer, G., O'Rourke, D., Stroud, D., et al. Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4). Genetics 200 (2015), 237–253.
-
(2015)
Genetics
, vol.200
, pp. 237-253
-
-
Loer, C.M.1
Calvo, A.C.2
Watschinger, K.3
Werner-Felmayer, G.4
O'Rourke, D.5
Stroud, D.6
-
24
-
-
82955245629
-
A role for calcineurin in Alzheimer's disease
-
Reese, L.C., Taglialatela, G., A role for calcineurin in Alzheimer's disease. Curr Neuropharmacol 9 (2011), 685–692.
-
(2011)
Curr Neuropharmacol
, vol.9
, pp. 685-692
-
-
Reese, L.C.1
Taglialatela, G.2
-
25
-
-
33845425431
-
Regulation of phosphorylation of tau by protein kinases in rat brain
-
Sengupta, A., Grundke-Iqbal, I., Iqbal, K., Regulation of phosphorylation of tau by protein kinases in rat brain. Neurochem Res 31 (2006), 1473–1480.
-
(2006)
Neurochem Res
, vol.31
, pp. 1473-1480
-
-
Sengupta, A.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
26
-
-
85016403555
-
Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry
-
De Deurwaerdère, P., Di Giovanni, G., Millan, M.J., Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry. Prog Neurobiol 151 (2017), 57–100.
-
(2017)
Prog Neurobiol
, vol.151
, pp. 57-100
-
-
De Deurwaerdère, P.1
Di Giovanni, G.2
Millan, M.J.3
-
27
-
-
27544485773
-
The intermolecular Pictet-Spengler condensation with chiral carbonyl derivatives in the stereoselective syntheses of optically-active isoquinoline and indole alkaloids
-
Larghi, E.L., Amongero, M., Bracca, A.B.J., Kaufman, T.S., The intermolecular Pictet-Spengler condensation with chiral carbonyl derivatives in the stereoselective syntheses of optically-active isoquinoline and indole alkaloids. ARKIVOC 12 (2005), 98–153.
-
(2005)
ARKIVOC
, vol.12
, pp. 98-153
-
-
Larghi, E.L.1
Amongero, M.2
Bracca, A.B.J.3
Kaufman, T.S.4
-
28
-
-
84894494592
-
Mammalian dopa decarboxylase: Structure, catalytic activity and inhibition
-
Bertoldi, M., Mammalian dopa decarboxylase: Structure, catalytic activity and inhibition. Arch Biochem Biophys 546 (2014), 1–7.
-
(2014)
Arch Biochem Biophys
, vol.546
, pp. 1-7
-
-
Bertoldi, M.1
-
29
-
-
77649179779
-
Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat
-
Lebel, M., Chagniel, L., Bureau, G., Cyr, M., Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat. Neurobiol Dis 38 (2010), 59–67.
-
(2010)
Neurobiol Dis
, vol.38
, pp. 59-67
-
-
Lebel, M.1
Chagniel, L.2
Bureau, G.3
Cyr, M.4
-
30
-
-
84947907975
-
Levodopa/bensarazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats
-
Xie, C.L., Wang, W.W., Zhang, S.F., Yuan, M.L., Che, J.Y., Gan, J., et al. Levodopa/bensarazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats. Sci Rep, 4, 2014, 7506.
-
(2014)
Sci Rep
, vol.4
, pp. 7506
-
-
Xie, C.L.1
Wang, W.W.2
Zhang, S.F.3
Yuan, M.L.4
Che, J.Y.5
Gan, J.6
-
31
-
-
84863431577
-
Acute administration of L-Dopa induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain
-
Bottiglieri, T., Arning, E., Wasek, B., Nunbhakdi-Craig, V., Sontag, J.M., Sontag, E., Acute administration of L-Dopa induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain. J Neurosci 32 (2012), 9173–9181.
-
(2012)
J Neurosci
, vol.32
, pp. 9173-9181
-
-
Bottiglieri, T.1
Arning, E.2
Wasek, B.3
Nunbhakdi-Craig, V.4
Sontag, J.M.5
Sontag, E.6
-
32
-
-
84979561857
-
Regulation of tyrosine hydroxylase expression and phosphorylation in dopamine transporter-deficient mice
-
Salvatore, M.F., Calipari, E.S., Jones, S.R., Regulation of tyrosine hydroxylase expression and phosphorylation in dopamine transporter-deficient mice. ACS Chem Neurosci 7 (2016), 941–951.
-
(2016)
ACS Chem Neurosci
, vol.7
, pp. 941-951
-
-
Salvatore, M.F.1
Calipari, E.S.2
Jones, S.R.3
-
33
-
-
84873570633
-
Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency
-
Lee, N.C., Shieh, Y.D., Chien, Y.H., Tzen, K.Y., Yu, I.S., Chen, P.W., et al. Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency. Neurobiol Dis 52 (2013), 177–190.
-
(2013)
Neurobiol Dis
, vol.52
, pp. 177-190
-
-
Lee, N.C.1
Shieh, Y.D.2
Chien, Y.H.3
Tzen, K.Y.4
Yu, I.S.5
Chen, P.W.6
-
34
-
-
84891536562
-
The LIM and POU homeobox genes ttx-3 and unc-86 act as terminal selectors in distinct cholinergic and serotonergic neuron types
-
Zhang, F., Bhattacharya, A., Nelson, J.C., Abe, N., Gordon, P., Lloret-Fernandez, C., et al. The LIM and POU homeobox genes ttx-3 and unc-86 act as terminal selectors in distinct cholinergic and serotonergic neuron types. Development 141 (2014), 422–435.
-
(2014)
Development
, vol.141
, pp. 422-435
-
-
Zhang, F.1
Bhattacharya, A.2
Nelson, J.C.3
Abe, N.4
Gordon, P.5
Lloret-Fernandez, C.6
-
35
-
-
56049085197
-
Enhancing aromatic L-amino acid decarboxylase activity: implications for L-DOPA treatment in Parkinson's disease
-
Hadjiconstatinou, M., Neff, N.H., Enhancing aromatic L-amino acid decarboxylase activity: implications for L-DOPA treatment in Parkinson's disease. CNS Neurosci Ther 14 (2008), 340–351.
-
(2008)
CNS Neurosci Ther
, vol.14
, pp. 340-351
-
-
Hadjiconstatinou, M.1
Neff, N.H.2
-
36
-
-
3042548403
-
The GABA nervous system in C. elegans
-
Schuske, K., Beg, A.A., Jorgensen, E.M., The GABA nervous system in C. elegans. Trends Neurosci 27 (2004), 407–414.
-
(2004)
Trends Neurosci
, vol.27
, pp. 407-414
-
-
Schuske, K.1
Beg, A.A.2
Jorgensen, E.M.3
|